Death and morbidity from supratherapeutic dosing of colchicine

Medical Journal of Australia

Volumn 194, Issue 11, 2011, Pages 612-613

  Smith, Myles WH ^a   Roberts, Darren M ^a   Ritson, Siobhann M ^a   Day, Richard O ^a  

^a ST VINCENT S HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CLINDAMYCIN; COLCHICINE; GLYCOPROTEIN P INHIBITOR; PLACEBO;

ABDOMINAL TENDERNESS; AGED; AORTA BALLOON; CASE REPORT; CONSERVATIVE TREATMENT; CREATINE KINASE BLOOD LEVEL; DEHYDRATION; DIAPHORESIS; DIARRHEA; DRUG CONTRAINDICATION; DRUG DOSE COMPARISON; DRUG DOSE TITRATION; DRUG FATALITY; DRUG FEVER; DRUG MEGADOSE; FEMALE; HUMAN; HYPOTENSION; KIDNEY DYSFUNCTION; LETHARGY; LETTER; LIVER DYSFUNCTION; LOW DRUG DOSE; MALE; MORBIDITY; MULTIPLE ORGAN FAILURE; MYALGIA; NAUSEA; PANCYTOPENIA; PATIENT EDUCATION; RECOMMENDED DRUG DOSE; REPEATED DRUG DOSE; RESUSCITATION; RHABDOMYOLYSIS; SEPSIS; SIDE EFFECT; TACHYCARDIA; TACHYPNEA; VOMITING;

EID: 79958773652     PISSN: 0025729X     EISSN: 13265377     Source Type: Journal    
DOI: 10.5694/j.1326-5377.2011.tb03121.x     Document Type: Letter

References (5)

1. Rheumatology Expert Group. Therapeutic guidelines: rheumatology. Version 1. Melbourne: Therapeutic Guidelines Limited, 2006.
2. Terkeltaub RA, Furst DE, Bennett K, et al. High versus low dosing of oral colchicine for early acute gout flare: Twenty-four-hour outcome of the first multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose-comparison colchicine study. Arthritis Rheum 2010; 62: 1060-1068.
3. Australian medicines handbook: AMH July 2010 edition. Adelaide: AMH, 2010.
4. National Prescribing Service. Colchicine for acute gout: updated information about dosing and drug interactions. NPS, 2010. http://www.nps.org.au/ health_professionals/publications/nps_radar/2010/ may_2010/brief_item_colchicine (accessed Oct 2010).
5. Finkelstein Y, Aks SE, Hutson JR, et al. Colchicine poisoning: the dark side of an ancient drug. Clin Toxicol (Phila) 2010; 48: 407-414.