The role of the interferon gamma release assay in assessing recent tuberculosis transmission in a hospital incident

PLoS ONE

Volumn 6, Issue 6, 2011, Pages

  Bradshaw, Louise ^a   Davies, Elizabeth ^b   Devine, Michael ^b   Flanagan, Peter ^b   Kelly, Paul ^b   O'Connor, Kevin ^b   Drobniewski, Francis ^a   Nikolayevskyy, Vladislav ^a   Abubakar, Ibrahim ^a  

^a PUBLIC HEALTH ENGLAND   (United Kingdom)

^b NORTHERN HEALTH AND SOCIAL CARE TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON;

ADULT; AGE; AGED; ARTICLE; BACTERIAL TRANSMISSION; CONTACT EXAMINATION; CONTROLLED STUDY; CYTOKINE RELEASE; DIAGNOSTIC VALUE; DISEASE ASSOCIATION; FEMALE; FOLLOW UP; HEALTH CARE PERSONNEL; HOSPITAL INFECTION; HUMAN; IMMUNE DEFICIENCY; INTERFERON GAMMA RELEASE ASSAY; LONG TERM EXPOSURE; LUNG TUBERCULOSIS; MAJOR CLINICAL STUDY; MALE; MULTIDRUG RESISTANT TUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS; OCCUPATIONAL EXPOSURE; SCREENING TEST; TUBERCULIN TEST; DEMOGRAPHY; DISEASE TRANSMISSION; HOSPITAL; IMMUNOASSAY; LATENT TUBERCULOSIS; METHODOLOGY; MIDDLE AGED; OBSERVER VARIATION; RISK; SECRETION; TUBERCULOSIS;

ADULT; DEMOGRAPHY; FEMALE; FOLLOW-UP STUDIES; HEALTH PERSONNEL; HOSPITALS; HUMANS; IMMUNOASSAY; INTERFERON-GAMMA; LATENT TUBERCULOSIS; MALE; MIDDLE AGED; OBSERVER VARIATION; ODDS RATIO; TUBERCULOSIS;

EID: 79958763835     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0020770     Document Type: Article

References (15)

1. Gandhi NR, Nunn P, Dheda K, Schaaf HS, Zignol M, et al. (2010) Multidrug-resistant and extensively drug-resistant tuberculosis: a threat to global control of tuberculosis. Lancet 375 (9728): 1830-1843.
2. Health Protection Agency Centre for Infections Tuberculosis in the UK: Annual report on tuberculosis surveillance in the UK 2009. London, Health Protection Agency.
3. National Collaborating Centre for Chronic Conditions Tuberculosis: Clinical diagnosis and management of tuberculosis, and management for its prevention and control. 2006. London, National Institute for Clinical Excellence.
4. Fraser A, Paul M, Attamna A, Leibovici L, Drugs for preventing tuberculosis in people at risk of multiple-drug-resistant pulmonary tuberculosis. 2006. Cochrane Database of Systematic Reviews: Infectious Diseases Group.
5. Communicable Disease Surveillance Centre (Northern Ireland) Epidemiology of Tuberculosis in Northern Ireland: Annual surveillance report 2007. Belfast.
6. Pai M, Riley LW, Colford JM Jr, (2010) Interferon-g assays in the immunodiagnosis of tuberculosis: a systematic review. Lancet Infectious Diseases 4 pp. 761-776.
7. Pai M, O'Brien R, (2007) Serial Testing for Tuberculosis: Can We Make Sense of T Cell Assay Conversions and Reversions? PLoS Medicine 4 (6 e208): 980-983.
8. Pai M, Dheda K, Cunningham J, Scano F, O'Brien R, (2007) T-cell assays for the diagnosis of latent tuberculosis infection: Moving the research agenda forward. Lancet Infectious Diseases 7 (6): 428-438.
9. Hinks TSC, Dosanjh DPS, Innes JP, Pasvol G, Hackforth S, et al. (2009) Frequencies of Region of Difference-1 antigen-specific but not PPD-specific IFN-secreting T cells correlate with presence of tuberculosis disease but do not distinguish recent from remote infection. Infection and Immunity.
10. Cheesman EA, (1956) Pulmonary tuberculosis in Northern Ireland: An examination of the statistical data for 1948-54. British Journal of Preventive and Social Medicine 10 pp. 115-122.
11. Swindells JE, Aliyu SH, Enoch DA, Abubakar I, (2009) Role of interferon-gamma release assays in healthcare workers. Journal of Hospital Infection pp. 1-8.
12. van Zyl-Smit RN, Zwerling A, Dheda K, Pai M, Within-Subject Variability of Interferon-gamma Assay Results for Tuberculosis and Boosting Effect of Tuberculin Skin Testing: A Systematic Review. PLoS ONE 9 A D 4 (12): e8517.
13. Zwerling A, van den Hof S, Scholten J, Cobelens F, Menzies D, Pai M, (2011) Interferon-gamma release assays for tuberculosis screening of healthcare workers: a systematic review. Thorax.
14. Mack U, Migliori GB, Sester M, Rieder HL, Ehlers S, et al. (2009) LTBI: latent tuberculosis infection or lasting immune response to M. tuberculosis? A TBNET consensus statement. European Respiratory Journal 33: 956-973.
15. Pai M, (2010) Spectrum of latent tuberculosis - existing tests cannot resolve the underlying phenotypes. Nature Reviews Microbiology 8 (242).