메뉴 건너뛰기




Volumn 10, Issue 6, 2011, Pages 1072-1081

Combination radioimmunotherapy and chemoimmunotherapy involving different or the same targets improves therapy of human pancreatic carcinoma xenograft models

Author keywords

[No Author keywords available]

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; ANTIBODY CONJUGATE; ANTINEOPLASTIC AGENT; CLIVATUZUMAB TETRAXETAN Y 90; GEMCITABINE; HRS7 7 ETHYL 10 HYDROXYCAMPTOTHECIN ANTIBODY CONJUGATE; IMMU 132; IMMU 133; IMMU 134; IRINOTECAN; MUCIN; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; VELTUZUMAB 1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID Y 90; VELTUZUMAB 7 ETHYL 10 HYDROXYCAMPTOTHECIN ANTIBODY CONJUGATE;

EID: 79958751015     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-11-0115     Document Type: Article
Times cited : (41)

References (50)
  • 1
    • 14844343723 scopus 로고    scopus 로고
    • Perspectives on cancer therapy with radiolabeled monoclonal antibodies
    • Sharkey RM, Goldenberg DM. Perspectives on cancer therapy with radiolabeled monoclonal antibodies. J Nucl Med 2005;46 Suppl 1:115S-27S.
    • (2005) J Nucl Med , vol.46 , Issue.SUPPL. 1
    • Sharkey, R.M.1    Goldenberg, D.M.2
  • 2
    • 77954989427 scopus 로고    scopus 로고
    • 131I-tositumomab radioimmunotherapy: Initial tumor dose-response results using 3-dimensional dosimetry including radiobiologic modeling
    • 131I-tositumomab radioimmunotherapy: initial tumor dose-response results using 3-dimensional dosimetry including radiobiologic modeling. J Nucl Med 2010;51:1155-62.
    • (2010) J Nucl Med , vol.51 , pp. 1155-1162
    • Dewaraja, Y.K.1    Schipper, M.J.2    Roberson, P.L.3    Wilderman, S.J.4    Amro, H.5    Regan, D.D.6
  • 3
    • 78650868824 scopus 로고    scopus 로고
    • Radioimmunotherapy of solid tumors: Searching for the right target
    • Song H, Sgouros G. Radioimmunotherapy of solid tumors: searching for the right target. Curr Drug Deliv 2011;8:26-44.
    • (2011) Curr Drug Deliv , vol.8 , pp. 26-44
    • Song, H.1    Sgouros, G.2
  • 5
    • 0842285646 scopus 로고    scopus 로고
    • Antibody-induced intracellular signaling works in combination with radiation to eradicate lymphoma in radioimmunotherapy
    • DOI 10.1182/blood-2003-06-2037
    • Du Y, Honeychurch J, Cragg MS, Bayne M, Glennie MJ, Johnson PW, et al. Antibody-induced intracellular signaling works in combination with radiation to eradicate lymphoma in radioimmunotherapy. Blood 2004;103:1485-94. (Pubitemid 38168666)
    • (2004) Blood , vol.103 , Issue.4 , pp. 1485-1494
    • Du, Y.1    Honeychurch, J.2    Cragg, M.S.3    Bayne, M.4    Glennie, M.J.5    Johnson, P.W.M.6    Illidge, T.M.7
  • 8
    • 78650286160 scopus 로고    scopus 로고
    • Investigational antibody-drug conjugates for hematological malignancies
    • Polson AG, Ho WY, Ramakrishnan V. Investigational antibody-drug conjugates for hematological malignancies. Expert Opin Investig Drugs 2011;20:75-85.
    • (2011) Expert Opin Investig Drugs , vol.20 , pp. 75-85
    • Polson, A.G.1    Ho, W.Y.2    Ramakrishnan, V.3
  • 9
    • 74849092615 scopus 로고    scopus 로고
    • Antibody-drug conjugate targets
    • Teicher BA. Antibody-drug conjugate targets. Curr Cancer Drug Targets 2009;9:982-1004.
    • (2009) Curr Cancer Drug Targets , vol.9 , pp. 982-1004
    • Teicher, B.A.1
  • 10
    • 79952092706 scopus 로고    scopus 로고
    • Phase II study of the antibody drug conjugate trastuzumab-DM1 for the treatment of human epidermal growth factor receptor 2 (HER2)-positive breast cancer after prior HER2-directed therapy
    • Burris HA, 3rd, Rugo HS, Vukelja SJ, Vogel CL, Borson RA, Limentani S, et al. Phase II study of the antibody drug conjugate trastuzumab-DM1 for the treatment of human epidermal growth factor receptor 2 (HER2)-positive breast cancer after prior HER2-directed therapy. J Clin Oncol 2011;29:398-405.
    • (2011) J Clin Oncol , vol.29 , pp. 398-405
    • Burris III, H.A.1    Rugo, H.S.2    Vukelja, S.J.3    Vogel, C.L.4    Borson, R.A.5    Limentani, S.6
  • 11
    • 0037270737 scopus 로고    scopus 로고
    • The mechanism of action of radiosensitization of conventional chemotherapeutic agents
    • DOI 10.1053/srao.2003.50002
    • Lawrence TS, Blackstock AW, McGinn C. The mechanism of action of radiosensitization of conventional chemotherapeutic agents. Semin Radiat Oncol 2003;13:13-21. (Pubitemid 36173256)
    • (2003) Seminars in Radiation Oncology , vol.13 , Issue.1 , pp. 13-21
    • Lawrence, T.S.1    Blackstock, A.W.2    McGinn, C.3
  • 12
    • 29244465506 scopus 로고    scopus 로고
    • Biologic basis for combining drugs with radiation
    • DOI 10.1016/j.semradonc.2005.08.001, PII S1053429605000457, Concurrent Radiation/Drug Regimens Current and Horizons
    • Wilson GD, Bentzen SM, Harari PM. Biologic basis for combining drugs with radiation. Semin Radiat Oncol 2006;16:2-9. (Pubitemid 41832311)
    • (2006) Seminars in Radiation Oncology , vol.16 , Issue.1 , pp. 2-9
    • Wilson, G.D.1    Bentzen, S.M.2    Harari, P.M.3
  • 15
    • 0036291966 scopus 로고    scopus 로고
    • Paclitaxel as a radiation sensitizer for locally advanced pancreatic cancer
    • DOI 10.1016/S1040-8428(01)00184-6, PII S1040842801001846
    • Safran H, Rathore R. Paclitaxel as a radiation sensitizer for locally advanced pancreatic cancer. Crit Rev Oncol Hematol 2002;43:57-62. (Pubitemid 34722787)
    • (2002) Critical Reviews in Oncology/Hematology , vol.43 , Issue.1 , pp. 57-62
    • Safran, H.1    Rathore, R.2
  • 17
    • 23844507146 scopus 로고    scopus 로고
    • High-dose radioimmunotherapy combined with fixed, lowdose paclitaxel in metastatic prostate and breast cancer by using a MUC-1 monoclonal antibody, m170, linked to indium-111/yttrium-90 via a cathepsin cleavable linker with cyclosporine to prevent human anti-mouse antibody
    • Richman CM, Denardo SJ, O'Donnell RT, Yuan A, Shen S, Goldstein DS, et al. High-dose radioimmunotherapy combined with fixed, lowdose paclitaxel in metastatic prostate and breast cancer by using a MUC-1 monoclonal antibody, m170, linked to indium-111/yttrium-90 via a cathepsin cleavable linker with cyclosporine to prevent human anti-mouse antibody. Clin Cancer Res 2005;11:5920-7.
    • (2005) Clin Cancer Res , vol.11 , pp. 5920-5927
    • Richman, C.M.1    Denardo, S.J.2    O'Donnell, R.T.3    Yuan, A.4    Shen, S.5    Goldstein, D.S.6
  • 18
    • 19644379671 scopus 로고    scopus 로고
    • 90Y-labeled humanized anti-CEA monoclonal antibody with doxorubicin and peripheral blood stem cell rescue in advanced medullary thyroid cancer
    • 90Y-labeled humanized anti-CEA monoclonal antibody with doxorubicin and peripheral blood stem cell rescue in advanced medullary thyroid cancer. J Nucl Med 2005;46:620-33.
    • (2005) J Nucl Med , vol.46 , pp. 620-633
    • Sharkey, R.M.1    Hajjar, G.2    Yeldell, D.3    Brenner, A.4    Burton, J.5    Rubin, A.6
  • 19
    • 65249121939 scopus 로고    scopus 로고
    • A phase I study of a combination of yttrium-90-labeled anticarcinoembryonic antigen (CEA) antibody and gemcitabine in patients with CEA-producing advanced malignancies
    • Shibata S, Raubitschek A, Leong L, Koczywas M, Williams L, Zhan J, et al. A phase I study of a combination of yttrium-90-labeled anticarcinoembryonic antigen (CEA) antibody and gemcitabine in patients with CEA-producing advanced malignancies. Clin Cancer Res 2009;15:2935-41.
    • (2009) Clin Cancer Res , vol.15 , pp. 2935-2941
    • Shibata, S.1    Raubitschek, A.2    Leong, L.3    Koczywas, M.4    Williams, L.5    Zhan, J.6
  • 20
    • 1542405316 scopus 로고    scopus 로고
    • 90Yttrium-DOTA-labeled PAM4 antibody radioimmunotherapy and gemcitabine radiosensitization for the treatment of a human pancreatic cancer xenograft
    • 90Yttrium-DOTA-labeled PAM4 antibody radioimmunotherapy and gemcitabine radiosensitization for the treatment of a human pancreatic cancer xenograft. Int J Cancer 2004;109:618-26.
    • (2004) Int J Cancer , vol.109 , pp. 618-626
    • Gold, D.V.1    Modrak, D.E.2    Schutsky, K.3    Cardillo, T.M.4
  • 22
    • 0032169909 scopus 로고    scopus 로고
    • Camptothecins: A review of their development and schedules of administration
    • DOI 10.1016/S0959-8049(98)00229-9, PII S0959804998002299
    • O'Leary J, Muggia FM. Camptothecins: a review of their development and schedules of administration. Eur J Cancer 1998;34:1500-8. (Pubitemid 28446329)
    • (1998) European Journal of Cancer , vol.34 , Issue.10 , pp. 1500-1508
    • O'Leary, J.1    Muggia, F.M.2
  • 23
    • 79956008677 scopus 로고    scopus 로고
    • Humanized anti-Trop-2 IgG-SN-38 conjugate for effective treatment of diverse epithelial cancers: Preclinical studies in human cancer xenograft models and monkeys
    • Mar Epub ahead of print
    • Cardillo TM, Govindan SV, Sharkey RM, Trisal P, Goldenberg DM. Humanized anti-Trop-2 IgG-SN-38 conjugate for effective treatment of diverse epithelial cancers: preclinical studies in human cancer xenograft models and monkeys. Clin Cancer Res 2011 Mar 3 [Epub ahead of print].
    • (2011) Clin Cancer Res , vol.3
    • Cardillo, T.M.1    Govindan, S.V.2    Sharkey, R.M.3    Trisal, P.4    Goldenberg, D.M.5
  • 25
    • 77949907304 scopus 로고    scopus 로고
    • Multicenter study of radiosensitizing gemcitabine combined with fractionated radioimmunotherapy for repeated treatment cycles in advanced pancreatic cancer
    • Abstract 4620
    • Pennington K, Guarion MJ, Serafini AN, Rocah-Lima C, Suppiah K, Schneider CJ, et al. Multicenter study of radiosensitizing gemcitabine combined with fractionated radioimmunotherapy for repeated treatment cycles in advanced pancreatic cancer. J Clin Oncol 2009;27:231 Abstract 4620.
    • (2009) J Clin Oncol , vol.27 , pp. 231
    • Pennington, K.1    Guarion, M.J.2    Serafini, A.N.3    Rocah-Lima, C.4    Suppiah, K.5    Schneider, C.J.6
  • 26
    • 80054099263 scopus 로고    scopus 로고
    • Fractionated radioimmunotherapy with clivatuzumab tetraxetan combined with low-dose gemcitabine (Gem) is active in advanced pancreatic cancer (APC)
    • Abstract 240
    • Ocean AJ, Guarino MJ, Pennington KL, Montero AJ, Bekaii-Saab T, Gulec SA, et al. Fractionated radioimmunotherapy with clivatuzumab tetraxetan combined with low-dose gemcitabine (Gem) is active in advanced pancreatic cancer (APC). J Clin Oncol 2011;29:Abstract 240.
    • (2011) J Clin Oncol , vol.29
    • Ocean, A.J.1    Guarino, M.J.2    Pennington, K.L.3    Montero, A.J.4    Bekaii-Saab, T.5    Gulec, S.A.6
  • 27
    • 0028951289 scopus 로고
    • Targeting of xenografted pancreatic cancer with a new monoclonal antibody, PAM4
    • Gold DV, Alisauskas R, Sharkey RM. Targeting of xenografted pancreatic cancer with a new monoclonal antibody, PAM4. Cancer Res 1995;55:1105-10.
    • (1995) Cancer Res , vol.55 , pp. 1105-1110
    • Gold, D.V.1    Alisauskas, R.2    Sharkey, R.M.3
  • 28
    • 77951829072 scopus 로고    scopus 로고
    • Veltuzumab (humanized anti-CD20 monoclonal antibody): Characterization, current clinical results, and future prospects
    • Goldenberg DM, Morschhauser F, Wegener WA. Veltuzumab (humanized anti-CD20 monoclonal antibody): characterization, current clinical results, and future prospects. Leuk Lymphoma 2010;51:747-55.
    • (2010) Leuk Lymphoma , vol.51 , pp. 747-755
    • Goldenberg, D.M.1    Morschhauser, F.2    Wegener, W.A.3
  • 31
    • 70349685092 scopus 로고    scopus 로고
    • CEACAM5-targeted therapy of human colonic and pancreatic cancer xenografts with potent labetuzumab-SN-38 immunoconjugates
    • Govindan SV, Cardillo TM, Moon SJ, Hansen HJ, Goldenberg DM. CEACAM5-targeted therapy of human colonic and pancreatic cancer xenografts with potent labetuzumab-SN-38 immunoconjugates. Clin Cancer Res 2009;15:6052-61.
    • (2009) Clin Cancer Res , vol.15 , pp. 6052-6061
    • Govindan, S.V.1    Cardillo, T.M.2    Moon, S.J.3    Hansen, H.J.4    Goldenberg, D.M.5
  • 33
    • 77951614830 scopus 로고    scopus 로고
    • Monoclonal antibodies: Versatile platforms for cancer immunotherapy
    • Weiner LM, Surana R, Wang S. Monoclonal antibodies: versatile platforms for cancer immunotherapy. Nat Rev Immunol 2010;10:317-27.
    • (2010) Nat Rev Immunol , vol.10 , pp. 317-327
    • Weiner, L.M.1    Surana, R.2    Wang, S.3
  • 34
    • 34248190641 scopus 로고    scopus 로고
    • 131I-tositumomab (anti-CD20) radioimmunotherapy and autologous hematopoietic stem-cell transplantation for adults > or = 60 years old with relapsed or refractory B-cell lymphoma
    • 131I-tositumomab (anti-CD20) radioimmunotherapy and autologous hematopoietic stem-cell transplantation for adults > or = 60 years old with relapsed or refractory B-cell lymphoma. J Clin Oncol 2007;25:1396-402.
    • (2007) J Clin Oncol , vol.25 , pp. 1396-1402
    • Gopal, A.K.1    Rajendran, J.G.2    Gooley, T.A.3    Pagel, J.M.4    Fisher, D.R.5    Petersdorf, S.H.6
  • 41
    • 39749154101 scopus 로고    scopus 로고
    • Identification of Trop-2 as an oncogene and an attractive therapeutic target in colon cancers
    • DOI 10.1158/1535-7163.MCT-07-2003
    • Wang J, Day R, Dong Y, Weintraub SJ, Michel L. Identification of Trop-2 as an oncogene and an attractive therapeutic target in colon cancers. Mol Cancer Ther 2008;7:280-5. (Pubitemid 351302522)
    • (2008) Molecular Cancer Therapeutics , vol.7 , Issue.2 , pp. 280-285
    • Wang, J.1    Day, R.2    Dong, Y.3    Weintraub, S.J.4    Michel, L.5
  • 43
    • 50949103161 scopus 로고    scopus 로고
    • Rituximab blocks binding of radiolabeled anti-CD20 antibodies (Ab) but not radiolabeled anti-CD45 Ab
    • Gopal AK, Press OW, Wilbur SM, Maloney DG, Pagel JM. Rituximab blocks binding of radiolabeled anti-CD20 antibodies (Ab) but not radiolabeled anti-CD45 Ab. Blood 2008;112:830-5.
    • (2008) Blood , vol.112 , pp. 830-835
    • Gopal, A.K.1    Press, O.W.2    Wilbur, S.M.3    Maloney, D.G.4    Pagel, J.M.5
  • 44
    • 62449328137 scopus 로고    scopus 로고
    • Pretargeted versus directly targeted radioimmunotherapy combined with anti-CD20 antibody consolidation therapy of non-Hodgkin lymphoma
    • Sharkey RM, Karacay H, Johnson CR, Litwin S, Rossi EA, McBride WJ, et al. Pretargeted versus directly targeted radioimmunotherapy combined with anti-CD20 antibody consolidation therapy of non-Hodgkin lymphoma. J Nucl Med 2009;50:444-53.
    • (2009) J Nucl Med , vol.50 , pp. 444-453
    • Sharkey, R.M.1    Karacay, H.2    Johnson, C.R.3    Litwin, S.4    Rossi, E.A.5    McBride, W.J.6
  • 45
    • 77954913109 scopus 로고    scopus 로고
    • Potential of optimal preloading in anti-CD20 antibody radioimmunotherapy: An investigation based on pharmacokinetic modeling
    • Kletting P, Meyer C, Reske SN, Glatting G. Potential of optimal preloading in anti-CD20 antibody radioimmunotherapy: an investigation based on pharmacokinetic modeling. Cancer Biother Radiopharm 2010;25:279-87.
    • (2010) Cancer Biother Radiopharm , vol.25 , pp. 279-287
    • Kletting, P.1    Meyer, C.2    Reske, S.N.3    Glatting, G.4
  • 46
    • 33750549679 scopus 로고    scopus 로고
    • Novel SN-38-incorporating polymeric micelles, NK012, eradicate vascular endothelial growth factor-secreting bulky tumors
    • DOI 10.1158/0008-5472.CAN-06-1605
    • Koizumi F, Kitagawa M, Negishi T, Onda T, Matsumoto S, Hamaguchi T, et al. Novel SN-38-incorporating polymeric micelles, NK012, eradicate vascular endothelial growth factor-secreting bulky tumors. Cancer Res 2006;66:10048-56. (Pubitemid 44672058)
    • (2006) Cancer Research , vol.66 , Issue.20 , pp. 10048-10056
    • Koizumi, F.1    Kitagawa, M.2    Negishi, T.3    Onda, T.4    Matsumoto, S.-I.5    Hamaguchi, T.6    Matsumura, Y.7
  • 47
    • 41549105038 scopus 로고    scopus 로고
    • Novel delivery of SN38 markedly inhibits tumor growth in xenografts, including a camptothecin-11-refractory model
    • DOI 10.1158/1078-0432.CCR-07-4456
    • Sapra P, Zhao H, Mehlig M, Malaby J, Kraft P, Longley C, et al. Novel delivery of SN38 markedly inhibits tumor growth in xenografts, including a camptothecin-11-refractory model. Clin Cancer Res 2008;14: 1888-96. (Pubitemid 351469476)
    • (2008) Clinical Cancer Research , vol.14 , Issue.6 , pp. 1888-1896
    • Sapra, P.1    Zhao, H.2    Mehlig, M.3    Malaby, J.4    Kraft, P.5    Longley, C.6    Greenberger, L.M.7    Horak, I.D.8
  • 48
    • 59349100093 scopus 로고    scopus 로고
    • Clinical pharmacokinetics (PK) of EZN-2208, a novel anticancer agent, in patients (pts) with advanced malignancies: A phase I, first-in-human, dose-escalation study
    • Abstract 2556
    • Guo Z, Wheler JJ, Naing A, Mani S, Goel S, Mulcahy M, et al. Clinical pharmacokinetics (PK) of EZN-2208, a novel anticancer agent, in patients (pts) with advanced malignancies: a phase I, first-in-human, dose-escalation study. J Clin Oncol 2008;26:Abstract 2556.
    • (2008) J Clin Oncol , vol.26
    • Guo, Z.1    Wheler, J.J.2    Naing, A.3    Mani, S.4    Goel, S.5    Mulcahy, M.6
  • 49
    • 77958073029 scopus 로고    scopus 로고
    • Phase I study of NK012, a novel SN-38-incorporating micellar nanoparticle, in adult patients with solid tumors
    • Hamaguchi T, Doi T, Eguchi-Nakajima T, Kato K, Yamada Y, Shimada Y, et al. Phase I study of NK012, a novel SN-38-incorporating micellar nanoparticle, in adult patients with solid tumors. Clin Cancer Res 2010;16:5058-66.
    • (2010) Clin Cancer Res , vol.16 , pp. 5058-5066
    • Hamaguchi, T.1    Doi, T.2    Eguchi-Nakajima, T.3    Kato, K.4    Yamada, Y.5    Shimada, Y.6
  • 50
    • 65549151884 scopus 로고    scopus 로고
    • Antibody-drug conjugates for the treatment of non-Hodgkin's lymphoma: Target and linker-drug selection
    • Polson AG, Calemine-Fenaux J, Chan P, Chang W, Christensen E, Clark S, et al. Antibody-drug conjugates for the treatment of non-Hodgkin's lymphoma: target and linker-drug selection. Cancer Res 2009;69:2358-64.
    • (2009) Cancer Res , vol.69 , pp. 2358-2364
    • Polson, A.G.1    Calemine-Fenaux, J.2    Chan, P.3    Chang, W.4    Christensen, E.5    Clark, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.