Cytochrome P450 (CYP2D6) genotype is associated with elevated systolic blood pressure in preterm infants after discharge from the neonatal intensive care unit

Journal of Pediatrics

Volumn 159, Issue 1, 2011, Pages 104-109

  Dagle, John M ^a   Fisher, Tyler J ^a   Haynes, Susan E ^a   Berends, Susan K ^a   Brophy, Patrick D ^a   Morriss Jr , Frank H ^a   Murray, Jeffrey C ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIHYPERTENSIVE AGENT; CYTOCHROME P450 2D6; DNA; GLUCOCORTICOID;

ALLELE; ANTIHYPERTENSIVE THERAPY; ARTICLE; COHORT ANALYSIS; ELEVATED SYSTOLIC BLOOD PRESSURE; FEMALE; GENETIC RISK; GENOTYPE; GESTATIONAL AGE; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; NEWBORN; NEWBORN INTENSIVE CARE; OUTPATIENT CARE; OXYGEN THERAPY; PHENOTYPE; PREMATURITY; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTOLIC HYPERTENSION; URINARY TRACT INFECTION;

COHORT STUDIES; CYTOCHROME P-450 CYP2D6; FEMALE; GENE FREQUENCY; GENOTYPE; GLUCOCORTICOIDS; HUMANS; HYPERTENSION; INFANT, NEWBORN; INFANT, PREMATURE; INTENSIVE CARE UNITS, NEONATAL; MALE; MULTIVARIATE ANALYSIS; OXYGEN INHALATION THERAPY; PATIENT DISCHARGE; POLYMORPHISM, SINGLE NUCLEOTIDE; RETROSPECTIVE STUDIES; SYSTOLE; URINARY TRACT INFECTIONS;

EID: 79958715398     PISSN: 00223476     EISSN: 10976833     Source Type: Journal    
DOI: 10.1016/j.jpeds.2011.01.002     Document Type: Article

References (30)

1. Johansson S, Iliadou A, Bergvall N, Tuvemo T, Norman M, Cnattingius S. Risk of high blood pressure among young men increases with the degree of immaturity at birth. Circulation 2005;112:3430-6. (Pubitemid 43739558)
2. Kistner A, Celsi G, Vanpee M, Jacobson SH. Increased blood pressure but normal renal function in adult women born preterm. Pediatr Nephrol 2000;15:215-20.
3. Yiu V, Buka S, Zurakowski D, McCormick M, Brenner B, Jabs K. Relationship between birthweight and blood pressure in childhood. Am J Kidney Dis 1999;33:253-60. (Pubitemid 29072225)
4. Hovi P, Andersson S, Raikkonen K, Strang-Karlsson S, Jarvenpaa AL, Eriksson JG, et al. Ambulatory blood pressure in young adults with very low birth weight. J Pediatr 2010;156:54-9.
5. Johansson S, Norman M, Legnevall L, Dalmaz Y, Lagercrantz H, Vanpee M. Increased catecholamines and heart rate in children with low birth weight: perinatal contributions to sympathoadrenal overactivity. J Intern Med 2007;261:480-7. (Pubitemid 46587720)
6. Cheung YF, Wong KY, Lam BC, Tsoi NS. Relation of arterial stiffness with gestational age and birth weight. Arch Dis Child 2004;89:217-21. (Pubitemid 38325809)
7. Manalich R, Reyes L, Herrera M, Melendi C, Fundora I. Relationship between weight at birth and the number and size of renal glomeruli in humans: a histomorphometric study. Kidney Int 2000;58:770-3. (Pubitemid 30620027)
8. National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents. The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics 2004;114:555-76.
9. Northern Neonatal Nursing Initiative. Systolic blood pressure in babies of less than 32 weeks gestation in the first year of life. Arch Dis Child Fetal Neonatal Ed 1999;80:F38-42.
10. Abman SH, Warady BA, Lum GM, Koops BL. Systemic hypertension in infants with bronchopulmonary dysplasia. J Pediatr 1984;104:928-31. (Pubitemid 14119971)
11. Anderson AH, Warady BA, Daily DK, Johnson JA, Thomas MK. Systemic hypertension in infants with severe bronchopulmonary dysplasia: associated clinical factors. Am J Perinatol 1993;10:190-3. (Pubitemid 23151518)
12. Alagappan A, Malloy MH. Systemic hypertension in very low-birth weight infants with bronchopulmonary dysplasia: incidence and risk factors. Am J Perinatol 1998;15:3-8. (Pubitemid 28072969)
13. National Heart, Lung, and Blood Institute. Second Task Force on Blood Pressure Control in Children. Report of the Second Task Force on Blood Pressure Control in Children, 1987. Pediatrics 1987;79:1-25.
14. Ehn NL, Cooper ME, Orr K, Shi M, Johnson MK, Caprau D, et al. Evaluation of fetal and maternal genetic variation in the progesterone receptor gene for contributions to preterm birth. Pediatr Res 2007;62:630-5. (Pubitemid 351339003)
15. Horvath S, Xu X, Laird NM. The Family-Based Association Test method: strategies for studying general genotype-phenotype associations. Eur J Hum Genet 2001;9:301-6. (Pubitemid 32366699)
16. Laird NM, Horvath S, Xu X. Implementing a unified approach to family-based tests of association. Genet Epidemiol 2000;19(Suppl 1): S36-42.
17. Rabinowitz D, Laird N. A unified approach to adjusting association tests for population admixture with arbitrary pedigree structure and arbitrary missing marker information. Hum Hered 2000;50:211-23. (Pubitemid 30232624)
18. Allen J, Zwerdling R, Ehrenkranz R, Gaultier C, Geggel R, Greenough A, et al. Statement on the care of the child with chronic lung disease of infancy and childhood. Am J Respir Crit Care Med 2003;168:356-96.
19. Zhou SF, Liu JP, Chowbay B. Polymorphism of human cytochrome P450 enzymes and its clinical impact. Drug Metab Rev 2009;41:89-295.
20. Gaedigk A, Simon SD, Pearce RE, Bradford LD, Kennedy MJ, Leeder JS. The CYP2D6 activity score: translating genotype information into a qualitative measure of phenotype. Clin Pharmacol Ther 2008;83:234-42.
21. Teh LK, Zilfalil BA, Marina I, Rosemi BS, Ismail R. Genetic polymorphism of CYP2D6 in patients with cardiovascular disease: a cohort study. J Clin Pharm Ther 2004;29:559-64. (Pubitemid 40007083)
22. Lewington S, Clarke R, Qizilbash N, Peto R, Collins R, Prospective Studies C. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 2002;360:1903-13. (Pubitemid 35472129)
23. Zoccal DB, Bonagamba LG, Oliveira FR, Antunes-Rodrigues J, Machado BH. Increased sympathetic activity in rats submitted to chronic intermittent hypoxia. Exp Physiol 2007;92:79-85. (Pubitemid 46096255)
24. Gonzalez-Martin MC, Vega-Agapito V, Prieto-Lloret J, Agapito MT, Castaneda J, Gonzalez C. Effects of intermittent hypoxia on blood gases plasma catecholamine and blood pressure. Adv Exp Med Biol 2009;648: 319-28.
25. Yzydorczyk C, Comte B, Cambonie G, Lavoie JC, Germain N, Ting Shun Y, et al. Neonatal oxygen exposure in rats leads to cardiovascular and renal alterations in adulthood. Hypertension 2008;52:889-95.
26. Murray J, Taylor SW, Zhang B, Ghosh SS, Capaldi RA. Oxidative damage to mitochondrial complex I due to peroxynitrite: identification of reactive tyrosines by mass spectrometry. J Biol Chem 2003;278:37223-30. (Pubitemid 37175238)
27. Short EJ, Klein NK, Lewis BA, Fulton S, Eisengart S, Kercsmar C, et al. Cognitive and academic consequences of bronchopulmonary dysplasia and very low birth weight: 8-year-old outcomes. Pediatrics 2003;112: e359.
28. Wilson-Costello D, Walsh MC, Langer JC, Guillet R, Laptook AR, Stoll BJ, et al. Impact of postnatal corticosteroid use on neurodevelopment at 18 to 22 months' adjusted age: effects of dose, timing, and risk of bronchopulmonary dysplasia in extremely low birth weight infants. Pediatrics 2009;123:e430-7.
29. Shaltout HA, Figueroa JP, Rose JC, Diz DI, Chappell MC. Alterations in circulatory and renal angiotensin-converting enzyme and angiotensin-converting enzyme 2 in fetal programmed hypertension. Hypertension 2009;53:404-8.
30. Wells JC. The thrifty phenotype as an adaptive maternal effect. Biol Rev Camb Philos Soc 2007;82:143-72.