Isolated perfused murine lung: A well characterized preparation for studying lung vascular function

Drug Discovery Today: Disease Models

Volumn 7, Issue 3-4, 2010, Pages 131-135

  Herget, Jan ^a   Chovanec, Milan ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

BOVINE SERUM ALBUMIN; SODIUM CHLORIDE;

ARTICLE; BLOOD; HYPOXIA; ISOLATED LUNG; LUNG EDEMA; LUNG FUNCTION; LUNG HEMODYNAMICS; LUNG PERFUSION; LUNG VASOCONSTRICTION; LUNG VENTILATION; NONHUMAN; PERFUSION PRESSURE; PULMONARY HYPERTENSION; THERMOREGULATION; TISSUE PREPARATION;

EID: 79958712590     PISSN: 17406757     EISSN: 17406757     Source Type: Journal    
DOI: 10.1016/j.ddmod.2011.03.008     Document Type: Review

References (29)

1. T.G. Brodie The perfusion of surviving organs J. Physiol. 29 1903 266 275
2. A. Linder The ex-vivo isolated, perfused human lung model: description and potential applications Thorac. Cardiovasc. Surg. 44 1996 140 146 (Pubitemid 26246968)
3. F.P. Knowlton, and E.H. Starling Experiments on the consumption of sugar in the normal and the diabetic heart J. Physiol. 45 1912 146 163
4. I.F. McMurtry Inhibition of hypoxic pulmonary vasoconstriction by calcium antagonists in isolated rat lungs Circ. Res. 38 1976 99 104
5. I.F. McMurtry Angiotensin is not required for hypoxic constriction in salt solution-perfused rat lungs J. Appl. Physiol. 56 1984 375 380 (Pubitemid 14143694)
6. J. Herget, and I.F. McMurtry Dexamethasone potentiates hypoxic vasoconstriction in salt solution-perfused rat lungs Am. J. Physiol. 253 Pt 2 1987 H574 581
7. S. Levey, and R. Gast Isolated perfused rat lung preparation J. Appl. Physiol. 21 1966 313 316
8. de Burgh Daly, I. and Hebb, C. (1966) Pulmonary and Bronchial Vascular Systems, pp. 350-373, Edward Arnold (Publishers) Ltd
9. R.W. Niemeier, and E. Bingham An isolated perfused lung preparation for metabolic studies Life Sci. II 11 1972 807 820
10. J. Herget, and I.F. Murtry Mc Effects of ouabain, low K+, and aldosterone on hypoxic pressor reactivity of rat lungs Am. J. Physiol. 248 1985 H55 H60
11. J. Herget, and V. Kuklik Perinatal lung injury extends in adults the site of hypoxic pulmonary vasoconstriction upstream Physiol. Res. 44 1995 25 30
12. J. Herget Adrenalectomy depresses hypoxic pulmonary vasoconstriction in vitro but does not attenuate the pulmonary hypertension of chronic hypoxia in vivo Exp. Clin. Cardiol. 3 1998 28 32
13. D. Hodyc Superoxide dismutase mimetic tempol inhibits hypoxic pulmonary vasoconstriction in rats independently of nitric oxide production Exp. Physiol. 92 2007 945 951 (Pubitemid 47283897)
14. D. Hodyc Pre-arrest administration of the cell-permeable free radical scavenger tempol reduces warm ischemic damage of lung function in non-heart-beating donors J. Heart Lung Transplant. 27 2008 890 897
15. R.W. Niemeier The isolated perfused lung Environ. Health Perspect. 56 1984 35 41 (Pubitemid 14070477)
16. C.E. Bernard An isolated perfused lung model with real time data collection and analysis of lung function J. Pharmacol. Toxicol. Methods 38 1997 41 46 (Pubitemid 27460599)
17. F. Petak Lung mechanical and vascular changes during positive-and negative-pressure lung inflations: importance of reference pressures in the pulmonary vasculature J. Appl. Physiol. 106 2009 935 942
18. J. Czartolomna Permeability characteristics of isolated perfused rat lungs J. Appl. Physiol. 70 1991 1854 1860
19. A.K. Sharma Protection from pulmonary ischemia-reperfusion injury by adenosine A2A receptor activation Respir. Res. 10 2009 58
20. G.R. Barer Reactivity and site of vasomotion in pulmonary vessels of chronically hypoxic rats: relation to structural changes Am. Rev. Respir. Dis. 140 1989 1483 1485 (Pubitemid 19276247)
21. T.S. Hakim Partitioning of pulmonary vascular resistance in dogs by arterial and venous occlusion J. Appl. Physiol. 52 1982 710 715 (Pubitemid 12041119)
22. T.S. Hakim Site of pulmonary hypoxic vasoconstriction studied with arterial and venous occlusion J. Appl. Physiol. 54 1983 1298 1302 (Pubitemid 13098979)
23. H. Konzett, and C.O. Hebb Vaso-and broncho-motor actions of noradrenaline (arterenol) and of adrenaline in the isolated perfused lungs of the dog Arch. Int. Pharmacodyn. Ther. 78 1949 210 224
24. C.A. Watkins, and D.E. Rannels In situ perfusion of rat lungs: stability and effects of oxygen tension J. Appl. Physiol. 47 1979 325 329 (Pubitemid 10241307)
25. R.A. Rhoades Isolated perfused lung preparation for studying altered gaseous environments Environ. Health Perspect. 56 1984 43 50 (Pubitemid 14070478)
26. D.W. Jirsch Twelve hour perfusion of isolated pulmonary lobes Chest 60 1971 44 48
27. J. Herget Pulmonary haemodynamics in acute experimental lung vascular injury Physiol. Res. 46 1997 341 344 (Pubitemid 27471199)
28. P.L. Khimenko Tumor necrosis factor-alpha in ischemia and reperfusion injury in rat lungs J. Appl. Physiol. 85 1998 2005 2011 (Pubitemid 28558052)
29. T.C. Isaacson Increased endothelium-derived NO in hypertensive pulmonary circulation of chronically hypoxic rats J. Appl. Physiol. 76 1994 933 940 (Pubitemid 24075646)