Phenotypic expression, body mass index and insulin resistance in relation to LH levels in women with polycystic ovary syndrome

European Journal of Obstetrics and Gynecology and Reproductive Biology

Volumn 156, Issue 2, 2011, Pages 181-185

  Katsikis, Ilias ^a   Karkanaki, Artemis ^a,c   Misichronis, Georgios ^a   Delkos, Dimitrios ^a   Kandaraki, Eleni A ^b   Panidis, Dimitrios ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^b UNIVERSITY OF ATHENS   (Greece)

^c NONE   (Greece)

Author keywords

1990 criteria; 2003 criteria; BMI; Insulin resistance; LH; LH FSH; PCOS; Phenotypes

Indexed keywords

ANDROGEN; FOLLITROPIN; GLUCOSE; INSULIN; LUTEINIZING HORMONE;

ADULT; ANTHROPOMETRY; AROMATIZATION; ARTICLE; BODY MASS; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; FOLLITROPIN BLOOD LEVEL; HUMAN; HYPOTHALAMUS; INSULIN RESISTANCE; LUTEINIZING HORMONE BLOOD LEVEL; LUTEINIZING HORMONE RELEASE; MAJOR CLINICAL STUDY; NEGATIVE FEEDBACK; OBESITY; OVARY FOLLICLE; OVARY POLYCYSTIC DISEASE; PHENOTYPE; PRIORITY JOURNAL;

EID: 79958295537     PISSN: 03012115     EISSN: 18727654     Source Type: Journal    
DOI: 10.1016/j.ejogrb.2011.01.023     Document Type: Article

References (30)

1. R.A. Lobo, O.A. Kletzky, J.D. Campeau, and G.S. di Zerega Elevated bioactive luteinizing hormone in women with polycystic ovary syndrome Fertil Steril 39 1983 674 678 (Pubitemid 13088051)
2. 4 -androstenedione levels in lean women with polycystic ovary syndrome Fertil Steril 84 2005 538 540 (Pubitemid 41125289)
3. E. Diamanti-Kandarakis, and D. Panidis Unraveling the phenotypic map of polycystic ovary syndrome Clin Endocrinol (Oxf) 67 2007 735 742
4. Zawadski JK, Dunaif A. Diagnostic criteria for polycystic ovary syndrome: towards a rational approach. In: Dunaif A, Givens JR, Haseltine FP, Merriam GE, editors. Hershman SM, series editor. Polycystic ovary syndrome. Current issues in endocrinology and metabolism. Boston: Blackwell Scientific Publications; 1992. p. 377-84.
5. The Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS) Hum Reprod 19 2004 41 47
6. The Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS) Fertil Steril 81 2004 19 25
7. R. Azziz, E. Carmina, and D. Dewailly Androgen Excess Society. Positions statement: criteria for defining polycystic ovary syndrome as a predominantly hyperandrogenic syndrome: an Androgen Excess Society guideline J Clin Endocrinol Metab 91 2006 4237 4245 (Pubitemid 44833391)
8. E. Carmina, and R.A. Lobo Do hyperandrogenic women with normal menses have polycystic ovary syndrome? Fertil Steril 71 1999 319 322 (Pubitemid 29069911)
9. F.J. Broekmans, E.A. Knauff, O. Valkenburg, J.S. Laven, M.J. Eijkemans, and B.C. Fauser PCOS according to the Rotterdam consensus criteria: change in prevalence among WHO-II anovulation and association with metabolic factors Br J Obstet Gynecol 113 2006 1210 1217 (Pubitemid 44401217)
10. C.K. Welt, J.A. Gudmundsson, G. Arason, J. Adams, H. Palsdottir, and G. Gudlaugsdottir Characterizing discrete subsets of polycystic ovary syndrome as defined by the Rotterdam criteria: the impact of weight on phenotype and metabolic features J Clin Endocrinol Metab 91 2006 4842 4848 (Pubitemid 44917316)
11. C. Moran, E. Garcia-Hernandez, E. Barahona, S. Gonzalez, and J. Bermudez Relationship between gonadotropin dissociation in obese and non-obese women with polycystic ovary syndrome Fertil Steril 80 2003 1466 1472 (Pubitemid 37532464)
12. A. Piouka, D. Farmakiotis, I. Katsikis, D. Macut, S. Gerou, and D. Panidis Anti-Mullerian hormone levels reflect severity of PCOS but are negatively influenced by obesity: relationship with increased luteinizing hormone levels Am J Physiol Endocrinol Metab 269 2009 E238 E243
13. Faul F, Erdfelder E. GPower: a priori, post hoc, and compromise power analyses for MS-DOS (computer program). Bonn, FRG: Bonn University, Department of Psychology, 1992.
14. J.E. Nestler Metformin for the treatment of the polycystic ovary syndrome N Engl J Med 358 2008 47 54
15. R.J. Norman, D. Dewailly, R.S. Legro, and T.E. Hickey Polycystic ovary syndrome Lancet 370 2007 685 697 (Pubitemid 47285318)
16. R.A. Ehrmann Polycystic ovary syndrome N Engl J Med 352 2005 323 336
17. G.W. DeVane, N.M. Czekala, H.L. Judd, and S.S. Yen Circulating gonadotropins, estrogens, and androgens in polycystic ovarian disease Am J Obstet Gynecol 121 1975 496 500
18. D.A. Ehrmann, R.L. Rosenfield, R.B. Barnes, D.F. Brigell, and Z. Sheikh Detection of functional ovarian hyperandrogenism in women with androgen excess N Engl J Med 327 1992 157 162
19. A. Lanzone, F. Petraglia, A.M. Fulghesu, M. Ciampelli, A. Caruso, and S. Mancuso Corticotropin-releasing hormone induces an exaggerated response of adrenocorticotropic hormone and cortisol in polycystic ovary syndrome Fertil Steril 63 1995 1195 1199
20. S.K. Blank, C.R. McCartney, and J.C. Marshall The origins and sequelae of abnormal neuroendocrine function in polycystic ovary syndrome Hum Reprod Update 12 2006 351 361 (Pubitemid 43923410)
21. A.E. Taylor, B. McCourt, and K.A. Martin Determinants of abnormal gonadotropins secretion in clinically defined women with polycystic ovary syndrome J Clin Endocrinol Metab 82 1997 2248 2256 (Pubitemid 27287593)
22. J. Waldstreicher, N.F. Santoro, J.E. Hall, M. Filicori, and W.F. Crowley Jr. Hyperfunction of the hypothalamic-pituitary axis in women with polycystic ovary syndrome J Clin Endocrinol Metab 66 1988 165 172
23. C.A. Eagleson, M.B. Gingrich, and C.L. Pastor Polycystic ovarian syndrome: evidence that flutamide restores sensitivity of the gonadotropin-releasing hormone pulse generator to inhibition by estradiol and progesterone J Clin Endocrinol Metab 85 2000 4047 4052 (Pubitemid 32055351)
24. J.C. Marshall, C.A. Eagleson, and C.R. McCartney Hypothalamic dysfunction Mol Cell Endocrinol 183 2001 29 32 (Pubitemid 32938508)
25. C.D. Edman, and P.C. MacDonald Effect of obesity on conversion of plasma androstendione to estrone in ovulatory and anovulatory young women Am J Obstet Gynecol 130 1978 456 461 (Pubitemid 8291953)
26. A. Dunaif, J. Mandeli, H. Fluhr, and A. Dobrjansky The impact of obesity and chronic hyperinsulinemia on gonadotropin release and gonadal steroid secretion in the polycystic ovary syndrome J Clin Endocrinol Metab 66 1988 131 139 (Pubitemid 18027742)
27. E. Diamanti-Kandarakis, and A. Dunaif New perspectives in polycystic ovary syndrome Trends Endocrinol Metab 1996 267 271 (Pubitemid 26349555)
28. C. Moran, E. Garcia-Hernandez, E. Barahona, S. Gonzalez, and J. Bermudez Relationship between gonadotropin dissociation in obese and obese and non-obese women with polycystic ovary syndrome Fertil Steril 80 2003 1466 1472 (Pubitemid 37532464)
29. E.Y. Adashi, A.J.W. Hsuech, and S.S.C. Yen Insulin enhancement of luteinizing hormone and follicle-stimulating hormone release by cultured pituitary cells Endocrinol 108 1981 1441 1449 (Pubitemid 11079170)
30. R.A. Lobo, O.A. Kletzky, J.D. Campeau, and G.S. di Zerega Elevated bioactive luteinizing hormone in women with the polycystic ovary syndrome Fertil Steril 39 1983 674 678 (Pubitemid 13088051)