Premature mortality in epilepsy: Is it preventable?

Expert Review of Neurotherapeutics

Volumn 11, Issue 6, 2011, Pages 767-770

  Neligan, Aidan ^a   Sander, Josemir W ^a,b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b STICHTING EPILEPSIE INSTELLINGEN NEDERLAND SEIN   (Netherlands)

Author keywords

drowning; epidemiology; epilepsy; mortality; SUDEP

Indexed keywords

ANTICONVULSIVE AGENT; PHENOBARBITAL;

ACCIDENT; ACCIDENT PREVENTION; ANTICONVULSANT THERAPY; DOSE RESPONSE; DROWNING; EPILEPSY; EPILEPTIC STATE; HIGH RISK POPULATION; HUMAN; MORTALITY; PATIENT EDUCATION; PREMATURE MORTALITY; REVIEW; RISK REDUCTION; SUDDEN DEATH;

EPILEPSY; HUMANS; META-ANALYSIS AS TOPIC; RISK;

EID: 79958291916     PISSN: 14737175     EISSN: 17448360     Source Type: Journal    
DOI: 10.1586/ern.11.72     Document Type: Review

References (32)

1. Shackleton DP, Westendorp RG, Trenite DG, et al. Mortality in patients with epilepsy: 40 years of follow up in a Dutch cohort study. J. Neurol. Neurosurg. Psychiatry 66, 636-640 (1999). (Pubitemid 29186972)
2. Hauser WA, Annegers JF, Elveback LR. Mortality in patients with epilepsy. Epilepsia 21, 399-412 (1980). (Pubitemid 10054081)
3. Olafsson E, Hauser WA, Gudmundsson G. Long-term survival of people with unprovoked seizures: a population-based study. Epilepsia 39, 89-92 (1998). (Pubitemid 28116847)
4. Lhatoo SD, Johnson AL, Goodridge DM, et al. Mortality in epilepsy in the first 11 to 14 years after diagnosis: multivariate analysis of a long-term, prospective, population-based cohort. Ann. Neurol. 49, 336-344 (2001). (Pubitemid 32202787)
5. Lindsten H, Nystrom L, Forsgren L. Mortality risk in an adult cohort with a newly diagnosed unprovoked epileptic seizure: a population-based study. Epilepsia 41, 1469-1473 (2000).
6. Neligan A, Bell GS, Shorvon SD, et al. Temporal trends in the mortality of people with epilepsy: a review. Epilepsia 51, 2241-2246 (2010).
7. Shackleton DP, Westendorp RG, Kasteleijn- Nolst Trenite DG, et al. Survival of patients with epilepsy: an estimate of the mortality risk. Epilepsia 43, 445-450 (2002). (Pubitemid 34297185)
8. Forsgren L, Hauser WA, Olafsson E, et al. Mortality of epilepsy in developed countries: a review. Epilepsia 46(Suppl. 11), 18-27 (2005). (Pubitemid 44922032)
9. Cockerell OC, Johnson AL, Sander JW, et al. Mortality from epilepsy: results from a prospective population-based study. Lancet 344, 918-921 (1994). (Pubitemid 24295878)
10. Loiseau J, Picot MC, Loiseau P. Short-term mortality after a first epileptic seizure: a population-based study. Epilepsia 40, 1388-1392 (1999). (Pubitemid 29471338)
11. Camfield CS, Camfield PR, Veugelers PJ. Death in children with epilepsy: a population-based study. Lancet 359, 1891-1895 (2002). (Pubitemid 34615766)
12. Bell GS, Gaitatzis A, Bell CL, et al. Drowning in people with epilepsy: how great is the risk? Neurology 71, 578-582 (2008).
13. Mu J, Liu L, Zhang Q, et al. Causes of deaths among people with convulsive epilepsy in rural China: a prospective study. Neurology (2011) (In press).
14. Ding D, Wang W, Wu J, et al. Premature mortality in people with epilepsy in rural China: a prospective study. Lancet Neurol. 5, 823-827 (2006). (Pubitemid 44780737)
15. Sillanpaa M, Shinnar S. Long-term mortality in childhood-onset epilepsy. N. Engl. J. Med. 363, 2522-2529 (2010).
16. Neligan A, Shorvon SD. Frequency and prognosis of convulsive status epilepticus of different causes: a systematic review. Arch. Neurol. 67, 931-940 (2010).
17. Wu YW, Shek DW, Garcia PA, et al. Incidence and mortality of generalized convulsive status epilepticus in California. Neurology 58, 1070-1076 (2002). (Pubitemid 34298548)
18. Lowenstein DH. Status epilepticus: an overview of the clinical problem. Epilepsia 40(Suppl. 1), 3-8 (1999).
19. Nashef L. Sudden unexpected death in epilepsy: terminology and definitions. Epilepsia 38 (Suppl. 11), 6-8 (1997).
20. Lhatoo SD, Sander JW. Cause-specific mortality in epilepsy. Epilepsia 46(Suppl. 11), 36-39 (2005). (Pubitemid 44922035)
21. Surges R, Thijs RD, Tan HL, et al. Sudden unexpected death in epilepsy: risk factors and potential pathomechanisms. Nat. Rev. Neurol. 5, 492-504 (2009).
22. Lhatoo SD, Langan Y, MacDonald BK, et al. Sudden unexpected death: a rare event in a large community based prospective cohort with newly diagnosed epilepsy and high remission rates. J. Neurol. Neurosurg. Psychiatry 66, 692-693 (1999). (Pubitemid 29186993)
23. Nilsson L, Farahmand BY, Persson PG, et al. Risk factors for sudden unexpected death in epilepsy: a case-control study. Lancet 353, 888-893 (1999). (Pubitemid 29126877)
24. Thom M, Seetah S, Sisodiya S, et al. Sudden and unexpected death in epilepsy (SUDEP): evidence of acute neuronal injury using HSP-7 and c-Jun immunohistochemistry. Neuropathol. Appl. Neurobiol. 29, 132-143 (2003). (Pubitemid 36408331)
25. Neligan A, Bell GS, Johnson AL, et al. The long-term risk of premature mortality in people with epilepsy. Brain 134, 388-395 (2011).
26. Neligan A, Bell GS, Johnson Al, et al. Long-term prognosis in people with epilepsy. Epilepsia 51 (Suppl. 4), 69-70 (2010).
27. Sperling MR, Feldman H, Kinman J, et al. Seizure control and mortality in epilepsy. Ann. Neurol. 46, 45-50 (1999). (Pubitemid 29314381)
28. Bell GS, Sinha S, Tisi J, et al. Premature mortality in refractory partial epilepsy: does surgical treatment make a difference? J. Neurol. Neurosurg. Psychiatry 81, 716-718 (2010).
29. Strauss DJ, Day SM, Shavelle RM, et al. Remote symptomatic epilepsy: does seizure severity increase mortality? Neurology 60, 395-399 (2003). (Pubitemid 36188232)
30. Mohanraj R, Norrie J, Stephen LJ, et al. Mortality in adults with newly diagnosed and chronic epilepsy: a retrospective comparative study. Lancet Neurol. 5, 481-487 (2006).
31. Faught E, Duh MS, Weiner JR, et al. Nonadherence to antiepileptic drugs and increased mortality: findings from the RANSOM study. Neurology 71, 1572-1578 (2008).
32. Morton B, Richardson A, Duncan S. Sudden unexpected death in epilepsy (SUDEP): don't ask, don't tell? J. Neurol. Neurosurg. Psychiatry 77, 199-202 (2006). (Pubitemid 43220842)