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Volumn 43, Issue 3, 2011, Pages 291-295

Protective effect of ethyl acetate fraction of Rhododendron arboreum flowers against carbon tetrachloride-induced hepatotoxicity in experimental models

Author keywords

Hepatotoxicity; phytochemicals; Rhododendron arboreum (Ericaceae) carbon tetrachloride

Indexed keywords

ACETIC ACID ETHYL ESTER; ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CARBON TETRACHLORIDE; GAMMA GLUTAMYLTRANSFERASE; GLUTATHIONE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; LIVER PROTECTIVE AGENT; MALONALDEHYDE; PLANT EXTRACT; RHODODENDRON ARBOREUM EXTRACT; SILYMARIN; UNCLASSIFIED DRUG;

EID: 79958285949     PISSN: 02537613     EISSN: 19983751     Source Type: Journal    
DOI: 10.4103/0253-7613.81518     Document Type: Article
Times cited : (38)

References (32)
  • 1
    • 0032983139 scopus 로고    scopus 로고
    • Development of phytomedicines for liver disease
    • Subramoniam P, Pushpangadan P. Development of phytomedicines for liver disease. Indian J Parmacol 1999;31:166-75.
    • (1999) Indian J Parmacol , vol.31 , pp. 166-175
    • Subramoniam, P.1    Pushpangadan, P.2
  • 2
    • 0842307101 scopus 로고    scopus 로고
    • Evaluation of hepatoprotective effect of Amalkadi Ghrita against carbon tetrachloride-induced hepatic damage in rats
    • DOI 10.1016/j.jep.2003.09.037
    • Achliya, GS, Wadodkar SG, Dorle AK. Evaluation of hepatoprotective effect of Ammalkadi ghrita against carbon tetrachloride induced hepatic damage in rats. J Ethnopharmacol 2004;90:229-32. (Pubitemid 38175413)
    • (2004) Journal of Ethnopharmacology , vol.90 , Issue.2-3 , pp. 229-232
    • Achliya, G.S.1    Wadodkar, S.G.2    Dorle, A.K.3
  • 4
    • 0029088967 scopus 로고
    • Flavonoidic constituents of Rhododendron arboreum leaves
    • Kamil M, Shafi ullah IM. Flavonoidic constituents of Rhododendron arboreum leaves Fitoterapia 1995;66:371-2.
    • (1995) Fitoterapia , vol.66 , pp. 371-372
    • Kamil, M.1    Shafiullah, I.M.2
  • 6
    • 0021018749 scopus 로고
    • Evaluation of 'Asoka Aristha' An indigenous medicine in Srilanka
    • Midlekoop TB, Labadie RP. Evaluation of 'Asoka Aristha' An indigenous medicine in Srilanka. J Ethnopharmacol 1983;8:13-20.
    • (1983) J Ethnopharmacol , vol.8 , pp. 13-20
    • Midlekoop, T.B.1    Labadie, R.P.2
  • 7
    • 77950299723 scopus 로고    scopus 로고
    • Antidiabetic Activity of Laligurans (Rhododendron arboreum Sm.) Flower
    • Bhandary MR, Kawabata J. Antidiabetic Activity of Laligurans (Rhododendron arboreum Sm.) Flower. J Food Sci Tech 2008;4:61-3.
    • (2008) J Food Sci Tech , vol.4 , pp. 61-63
    • Bhandary, M.R.1    Kawabata, J.2
  • 8
    • 79958292839 scopus 로고    scopus 로고
    • Anti-infl ammatory and antinociceptive activity of Rhododendron arboreum
    • Verma N, Singh AP, Amresh G, Sahu PK, Rao CV. Anti-infl ammatory and antinociceptive activity of Rhododendron arboreum. J Pharm Res 2010;3:1376-80.
    • (2010) J Pharm Res , vol.3 , pp. 1376-1380
    • Verma, N.1    Singh, A.P.2    Amresh, G.3    Sahu, P.K.4    Rao, C.V.5
  • 9
    • 79958252611 scopus 로고    scopus 로고
    • Diversity and indigenous household remedies of the inhabitants surrounding Mornaula reserve forest in West Himalaya
    • Pant S, Samant SS, Arya SC. Diversity and indigenous household remedies of the inhabitants surrounding Mornaula reserve forest in West Himalaya. Indian J Trad Know 2008;8:606-10.
    • (2008) Indian J Trad Know , vol.8 , pp. 606-610
    • Pant, S.1    Samant, S.S.2    Arya, S.C.3
  • 10
    • 0000087642 scopus 로고
    • The determination of bilirubin with photometric calorimeter
    • Malloy JR, Jollow, Evelyn KA. The determination of bilirubin with photometric calorimeter. J Biol Chem 1937;119:481-90.
    • (1937) J Biol Chem , vol.119 , pp. 481-490
    • Malloy, J.R.1    Jollow Evelyn, K.A.2
  • 11
    • 66349129125 scopus 로고
    • A Calorimetric method for the determination at serum glutamic oxaloacetic and glutamic pyruvic transaminases
    • Reitman S, Frankel S. A Calorimetric method for the determination at serum glutamic oxaloacetic and glutamic pyruvic transaminases. Am J Clin Path 1957;28:53-6.
    • (1957) Am J Clin Path , vol.28 , pp. 53-56
    • Reitman, S.1    Frankel, S.2
  • 12
    • 0014467815 scopus 로고
    • A kinetic photometric method for serum g-glutamyltranspeptidase
    • Szasz G. A kinetic photometric method for serum g-glutamyltranspeptidase. Clin Chem 1969;15:124-36.
    • (1969) Clin Chem , vol.15 , pp. 124-136
    • Szasz, G.1
  • 13
  • 14
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • DOI 10.1016/0003-2697(79)90738-3
    • Okhawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979;95:351-8. (Pubitemid 9194347)
    • (1979) Analytical Biochemistry , vol.95 , Issue.2 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 15
    • 0016275313 scopus 로고
    • Glutathone S-transferase: The first enzymatic step in mercapturic acid formation
    • Habig WH, Pabst MJ, Jakoby WB. Glutathone S-transferase: The first enzymatic step in mercapturic acid formation. J Biol Chem 1974;249:130-9.
    • (1974) J Biol Chem , vol.249 , pp. 130-139
    • Habig, W.H.1    Pabst, M.J.2    Jakoby, W.B.3
  • 16
    • 0001108928 scopus 로고
    • Hepatic glutathione reductase. I. Purifi cation and general kinetic properties
    • Mize CE, Langdon RG. Hepatic glutathione reductase. I. Purifi cation and general kinetic properties. J Biol Chem 1962;237:1589-95.
    • (1962) J Biol Chem , vol.237 , pp. 1589-1595
    • Mize, C.E.1    Langdon, R.G.2
  • 19
    • 0022600923 scopus 로고
    • The crucial role of low steady state oxygen partial pressures in haloalkane free-radical-mediated lipid peroxidation. Possible implications in haloalkane liver injury
    • DOI 10.1016/0006-2952(86)90546-0
    • De Groot H, Noll T. The crucial role of low steady state oxygen partial pressures in haloalkane free radical mediated lipid peroxidation. Biochem Pharmacol 1986;35:15-9. (Pubitemid 16161355)
    • (1986) Biochemical Pharmacology , vol.35 , Issue.1 , pp. 15-19
    • De Groot, H.1    Noll, T.2
  • 20
    • 0024540083 scopus 로고
    • Mechanism of carbon tetrachloride hepatotoxicity
    • Clawson GA. Mechanism of carbon tetrachloride hepatotoxicity. Pathol Immunol Res 1989;8:104-12.
    • (1989) Pathol Immunol Res , vol.8 , pp. 104-112
    • Clawson, G.A.1
  • 22
    • 0015687156 scopus 로고
    • Carbon tetrachloride hepatotoxicity: An example of lethal cleavage
    • Recknagel RO, Glende EA Jr. Carbon tetrachloride hepatotoxicity: An example of lethal cleavage. CRC Crit Rev Toxicol 1973;2:263-97.
    • (1973) CRC Crit Rev Toxicol , vol.2 , pp. 263-297
    • Recknagel, R.O.1    Glende Jr., E.A.2
  • 23
    • 0018347812 scopus 로고
    • Effects of carbon tetrachloride on isolated rat hepatocytes. Inhibition of protein and lipoprotein secretion
    • Gravela E, Albano E, Dianzani MU, Poli G, Slater TF. Effects of carbon tetrachloride on isolated rat hepatocytes: Inhibition of protein and lipoprotein secreation. Biochem J 1979;178:509-12. (Pubitemid 9152314)
    • (1979) Biochemical Journal , vol.178 , Issue.2 , pp. 509-512
    • Gravela, E.1    Albano, E.2    Dianzani, M.U.3
  • 24
    • 0019182285 scopus 로고
    • Metabolism of carbon tetrachloride in hepatic microsomes and reconstituted monooxygenase systems and its relationship to lipid peroxidation
    • Wolf CR, Harrelson WG Jr, Nastainczyk WM, Philpot RM, Kalyanaraman, B, Mason RP. Metabolism of carbon tetrachloride in hepatic microsomes and reconstituted monooxygenase systems and its relationship to lipid peroxidation. Mol Pharmacol 1980;18:553-8. (Pubitemid 11205388)
    • (1980) Molecular Pharmacology , vol.18 , Issue.3 , pp. 553-558
    • Wolf, C.R.1    Harrelson Jr., W.G.2    Nastainczyk, W.M.3
  • 26
    • 0002391242 scopus 로고
    • Free radical damage and lipid peroxidation
    • meeks RG, Harrison SD, Bull J, editors, Florida: CRC Press
    • Reckengel RO, Glende EA Jr, Britton RS. Free radical damage and lipid peroxidation. In: meeks RG, Harrison SD, Bull J, editors. Hepatotoxicology. Florida: CRC Press; 1991. p. 401.
    • (1991) Hepatotoxicology , pp. 401
    • Reckengel, R.O.1    Glende Jr., E.A.2    Britton, R.S.3
  • 27
    • 0021305589 scopus 로고
    • Studies of the relationship between the catalytic activity and binding of non-substrate ligands by the glutathione S-transferase
    • Boyer TD, Vessey DA, Holcomb C, Saley N. Studies of the relationship between the catalytic activity and binding of non-substrate ligands by the glutathione S-transferase. Biochem J 1984;217:179-85.
    • (1984) Biochem J , vol.217 , pp. 179-185
    • Boyer, T.D.1    Vessey, D.A.2    Holcomb, C.3    Saley, N.4
  • 28
    • 0022600522 scopus 로고
    • Possible regulation mechanism of microsomal glutathione S-transferase activity in rat liver
    • DOI 10.1016/0006-2952(86)90216-9
    • Masukawa T, Iwata H. Possible regulation mechanism of microsomal glutathione S-transferase activity in rat liver. Biochem Pharmacol 1986;35:435-8. (Pubitemid 16139466)
    • (1986) Biochemical Pharmacology , vol.35 , Issue.3 , pp. 435-438
    • Masukawa, T.1    Iwata, H.2
  • 29
    • 0019280984 scopus 로고
    • Physiological signifi cance of the glutathione S-transferases
    • Kaplowitz N. Physiological signifi cance of the glutathione S-transferases. Am J Physiol 1980;239:439-44.
    • (1980) Am J Physiol , vol.239 , pp. 439-444
    • Kaplowitz, N.1
  • 30
    • 77954660317 scopus 로고    scopus 로고
    • Glutathione reductase plays an anti-apoptotic role against oxidative stress in human hepatoma cells
    • Kim SJ, Jung HJ, Hyun DH, Park EH, Kim YM, Lim CJ. Glutathione reductase plays an anti-apoptotic role against oxidative stress in human hepatoma cells. Biochimie 2010;92:927-32.
    • (2010) Biochimie , vol.92 , pp. 927-932
    • Kim, S.J.1    Jung, H.J.2    Hyun, D.H.3    Park, E.H.4    Kim, Y.M.5    Lim, C.J.6
  • 32
    • 0037505644 scopus 로고    scopus 로고
    • Analysis of glutathione: Implication in redox and detoxification
    • DOI 10.1016/S0009-8981(03)00200-6
    • Pastore A, Federic G, Bertini E, Piemonte F. Analysis of glutathione: implication in redox and detoxifi cation. Clin Chim Acta 2003;333:19-39. (Pubitemid 36694824)
    • (2003) Clinica Chimica Acta , vol.333 , Issue.1-2 , pp. 19-39
    • Pastore, A.1    Federici, G.2    Bertini, E.3    Piemonte, F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.