메뉴 건너뛰기




Volumn 58, Issue 2, 2011, Pages 158-164

Silencing STAT3 may inhibit cell growth through regulating signaling pathway, telomerase, cell cycle, apoptosis and angiogenesis in hepatocellular carcinoma: Potential uses for gene therapy

Author keywords

Angiogenesis; Apoptosis; Cell cycle; Signaling pathway; STAT3; Telomerase

Indexed keywords

CASPASE 3; CYCLIN A; CYCLIN E; GELATINASE A; GLUCOSE REGULATED PROTEIN 78; HEAT SHOCK PROTEIN 27; PROTEIN P42; PROTEIN P44; SMAD3 PROTEIN; SMALL INTERFERING RNA; STAT3 PROTEIN; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE; VASCULOTROPIN A; X LINKED INHIBITOR OF APOPTOSIS; ANGIOGENIC FACTOR; STAT3 PROTEIN, HUMAN;

EID: 79958273935     PISSN: 00282685     EISSN: None     Source Type: Journal    
DOI: 10.4149/neo_2011_02_158     Document Type: Article
Times cited : (41)

References (40)
  • 1
    • 34848906227 scopus 로고    scopus 로고
    • Jak inhibitor induces S phase cell-cycle arrest and augments TRAIL-induced apoptosis in human hepatocellular carcinoma cells
    • doi:10.1016/j.bbrc.2007.09.049
    • FUKE H, SHIRAKI K, SUGIMOTO K, TANAKA J, BEPPU T, et al. Jak inhibitor induces S phase cell-cycle arrest and augments TRAIL-induced apoptosis in human hepatocellular carcinoma cells. Biochem Biophys Res Commun 2007; 363: 738-744. doi:10.1016/j.bbrc.2007.09.049
    • (2007) Biochem Biophys Res Commun , vol.363 , pp. 738-744
    • Fuke, H.1    Shiraki, K.2    Sugimoto, K.3    Tanaka, J.4    Beppu, T.5
  • 2
    • 56449108335 scopus 로고    scopus 로고
    • Mesothelin-induced pancreatic cancer cell proliferation involves alteration of cyclin E via activation of signal transducer and activator of transcription protein 3
    • doi:10.1158/1541-7786.MCR-08-0095
    • BHARADWAJ U, LI M, CHEN C, YAO Q. Mesothelin-induced pancreatic cancer cell proliferation involves alteration of cyclin E via activation of signal transducer and activator of transcription protein 3. Mol Cancer Res 2008; 6: 1755-1765. doi:10.1158/1541-7786.MCR-08-0095
    • (2008) Mol Cancer Res , vol.6 , pp. 1755-1765
    • Bharadwaj, U.1    Li, M.2    Chen, C.3    Yao, Q.4
  • 3
    • 34548260509 scopus 로고    scopus 로고
    • Abrogation of constitutive STAT3 activity sensitizes human hepatoma cells to TRAIL-mediated apoptosis
    • doi:10.1016/j.jhep.2007.04.017
    • KUSABA M, NAKAO K, GOTO T, NISHIMURA D, KAWASHIMO H, et al. Abrogation of constitutive STAT3 activity sensitizes human hepatoma cells to TRAIL-mediated apoptosis. J Hepatol 2007; 47: 546-555. doi:10.1016/j.jhep.2007.04.017
    • (2007) J Hepatol , vol.47 , pp. 546-555
    • Kusaba, M.1    Nakao, K.2    Goto, T.3    Nishimura, D.4    Kawashimo, H.5
  • 4
    • 64849088550 scopus 로고    scopus 로고
    • Characterization of STAT3 activation and expression in canine and human osteosarcoma
    • doi:10.1186/1471-2407-9-81
    • FOSSEY SL, LIAO AT, MCCLEESE JK, BEAR MD, LIN J, et al. Characterization of STAT3 activation and expression in canine and human osteosarcoma. BMC Cancer 2009; 9: 81. doi:10.1186/1471-2407-9-81
    • (2009) BMC Cancer , vol.9 , pp. 81
    • Fossey, S.L.1    Liao, A.T.2    McCleese, J.K.3    Bear, M.D.4    Lin, J.5
  • 5
    • 67649445779 scopus 로고    scopus 로고
    • Stat3-siRNA induces Fas-mediated apoptosis in vitro and in vivo in breast cancer
    • KUNIGAL S, LAKKA SS, SODADASU PK, ESTES N, RAO JS. Stat3-siRNA induces Fas-mediated apoptosis in vitro and in vivo in breast cancer. Int J Oncol 2009; 34: 1209-1220.
    • (2009) Int J Oncol , vol.34 , pp. 1209-1220
    • Kunigal, S.1    Lakka, S.S.2    Sodadasu, P.K.3    Estes, N.4    Rao, J.S.5
  • 6
    • 36148987265 scopus 로고    scopus 로고
    • Physiologically achievable concentrations of genistein enhance telomerase activity in prostate cancer cells via the activation of STAT3
    • doi:10.1093/carcin/bgm148
    • CHAU MN, EI TOUNY LH, JAGADEESH S, BANERJEE PP. Physiologically achievable concentrations of genistein enhance telomerase activity in prostate cancer cells via the activation of STAT3. Carcinogenesis 2007; 28: 2282-2290. doi:10.1093/carcin/bgm148
    • (2007) Carcinogenesis , vol.28 , pp. 2282-2290
    • Chau, M.N.1    Touny, L.H.E.2    Jagadeesh, S.3    Banerjee, P.P.4
  • 7
    • 8844220490 scopus 로고    scopus 로고
    • Stat3 upregulates MEK5 expression in human breast cancer cells
    • doi:10.1038/sj.onc.1208026
    • SONG H, JIN X, LIN J. Stat3 upregulates MEK5 expression in human breast cancer cells. Oncogene 2004; 23: 8301-8309. doi:10.1038/sj.onc.1208026
    • (2004) Oncogene , vol.23 , pp. 8301-8309
    • Song, H.1    Jin, X.2    Lin, J.3
  • 8
    • 0347986522 scopus 로고    scopus 로고
    • Stat3 modulates heat shock 27kDa protein expression in breast epithelial cells
    • doi:10.1016/j.bbrc.2003.12.048
    • SONG H, ETHIER SP, DZIUBINSKI ML, LIN J. Stat3 modulates heat shock 27kDa protein expression in breast epithelial cells. Biochem Biophys Res Commun 2004; 314: 143-150. doi:10.1016/j.bbrc.2003.12.048
    • (2004) Biochem Biophys Res Commun , vol.314 , pp. 143-150
    • Song, H.1    Ethier, S.P.2    Dziubinski, M.L.3    Lin, J.4
  • 9
    • 35948981785 scopus 로고    scopus 로고
    • Neuroendocrine modulation of signal transducer and activator of transcription-3 in ovarian cancer
    • doi:10.1158/0008-5472. CAN-07-0858
    • LANDEN CN Jr, LIN YG, ARMAIZ PENA GN, DAS PD, AREVALO JM, et al. Neuroendocrine modulation of signal transducer and activator of transcription-3 in ovarian cancer. Cancer Res 2007; 67: 10389-10396. doi:10.1158/0008-5472. CAN-07-0858
    • (2007) Cancer Res , vol.67 , pp. 10389-10396
    • Landen Jr, C.N.1    Lin, Y.G.2    Armaiz, P.G.N.3    Das, P.D.4    Arevalo, J.M.5
  • 10
    • 34247281958 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 3 activation promotes invasive growth of colon carcinomas through matrix metalloproteinase induction
    • doi:10.1593/neo.06820
    • TSAREVA SA, MORIGGL R, CORVINUS FM, WIEDERANDERS B, SCHUTZ A, et al. Signal transducer and activator of transcription 3 activation promotes invasive growth of colon carcinomas through matrix metalloproteinase induction. Neoplasia 2007; 9: 279-291. doi:10.1593/neo.06820
    • (2007) Neoplasia , vol.9 , pp. 279-291
    • Tsareva, S.A.1    Moriggl, R.2    Corvinus, F.M.3    Wiederanders, B.4    Schutz, A.5
  • 11
    • 34249902824 scopus 로고    scopus 로고
    • RNA interference-mediated signal transducers and activators of transcription 3 gene silencing inhibits invasion and metastasis of human pancreatic cancer cells
    • doi:10.1111/j.1349-7006.2007.00485.x
    • QIU Z, HUANG C, SUN J, QIU W, ZHANG J, et al. RNA interference-mediated signal transducers and activators of transcription 3 gene silencing inhibits invasion and metastasis of human pancreatic cancer cells. Cancer Sci 2007; 98: 1099-1106. doi:10.1111/j.1349-7006.2007.00485.x
    • (2007) Cancer Sci , vol.98 , pp. 1099-1106
    • Qiu, Z.1    Huang, C.2    Sun, J.3    Qiu, W.4    Zhang, J.5
  • 12
    • 33645532055 scopus 로고    scopus 로고
    • Activation of stat3 in human melanoma promotes brain metastasis
    • doi:10.1158/0008-5472. CAN-05-2674
    • XIE TX, HUANG FJ, ALDAPE KD, KANG SH, LIU M, et al. Activation of stat3 in human melanoma promotes brain metastasis. Cancer Res 2006; 66: 3188-3196. doi:10.1158/0008-5472. CAN-05-2674
    • (2006) Cancer Res , vol.66 , pp. 3188-3196
    • Xie, T.X.1    Huang, F.J.2    Aldape, K.D.3    Kang, S.H.4    Liu, M.5
  • 13
    • 20044376863 scopus 로고    scopus 로고
    • Activation of STAT3/Smad1 is a key signaling pathway for progression to glomerulosclerosis in experimental glomerulonephritis
    • doi:10.1074/jbc.M411064200
    • TAKAHASHI T, ABE H, ARAI H, MATSUBARA T, NAGAI K, et al. Activation of STAT3/Smad1 is a key signaling pathway for progression to glomerulosclerosis in experimental glomerulonephritis. J Biol Chem 2005; 280: 7100-7106. doi:10.1074/jbc.M411064200
    • (2005) J Biol Chem , vol.280 , pp. 7100-7106
    • Takahashi, T.1    Abe, H.2    Arai, H.3    Matsubara, T.4    Nagai, K.5
  • 14
    • 0347719405 scopus 로고    scopus 로고
    • Activation of Smad transcriptional activity by protein inhibitor of activated STAT3 (PIAS3)
    • doi:10.1073/pnas.0307598100
    • LONG J, WANG G, MATSUURA I, HE D, LIU F. Activation of Smad transcriptional activity by protein inhibitor of activated STAT3 (PIAS3). Proc Natl Acad Sci USA 2004; 101: 99-104. doi:10.1073/pnas.0307598100
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 99-104
    • Long, J.1    Wang, G.2    Matsuura, I.3    He, D.4    Liu, F.5
  • 15
    • 3042748279 scopus 로고    scopus 로고
    • Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells
    • doi:10.1186/ 1471-2407-3-23
    • LIZA K, MACIEJ K, MATHEW MK, BRENT HC. Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells. BMC Cancer 2003; 3: 23-32. doi:10.1186/ 1471-2407-3-23
    • (2003) BMC Cancer , vol.3 , pp. 23-32
    • Liza, K.1    Maciej, K.2    Mathew, M.K.3    Brent, H.C.4
  • 16
    • 66849094252 scopus 로고    scopus 로고
    • Applications of RNA interference in cancer therapeutics as a powerful tool for suppressing gene expression
    • [Epub ahead of print]
    • HE S, ZHANG D, CHENG F, GONG F, GUO Y. Applications of RNA interference in cancer therapeutics as a powerful tool for suppressing gene expression. Mol Biol Rep 2009; 1: [Epub ahead of print].
    • (2009) Mol Biol Rep , vol.1
    • He, S.1    Zhang, D.2    Cheng, F.3    Gong, F.4    Guo, Y.5
  • 17
    • 0035113393 scopus 로고    scopus 로고
    • Effect of phosphorylation of MAPK and Stat3 and expression of c-fos and c-jun proteins on hepatocarcinogenesis and their clinical significance
    • FENG DY, ZHENG H, TAN Y, CHENG RX. Effect of phosphorylation of MAPK and Stat3 and expression of c-fos and c-jun proteins on hepatocarcinogenesis and their clinical significance. World J Gastroenterol 2001; 7: 33-36.
    • (2001) World J Gastroenterol , vol.7 , pp. 33-36
    • Feng, D.Y.1    Zheng, H.2    Tan, Y.3    Cheng, R.X.4
  • 18
    • 26244439497 scopus 로고    scopus 로고
    • The Endogenous Ratio of Smad2 and Smad3 Influences the Cytostatic Function of Smad3
    • doi:10.1091/mbc.E05-01-0054
    • KIM SG, KIM HA, JONG HS, PARK JH, KIM NK, et al. The Endogenous Ratio of Smad2 and Smad3 Influences the Cytostatic Function of Smad3. Molecular Biology of the Cell 2005; 16: 4672-4683. doi:10.1091/mbc.E05-01-0054
    • (2005) Molecular Biology of the Cell , vol.16 , pp. 4672-4683
    • Kim, S.G.1    Kim, H.A.2    Jong, H.S.3    Park, J.H.4    Kim, N.K.5
  • 19
    • 1842828901 scopus 로고    scopus 로고
    • On the road to immortality: HTERT upregulation in cancercells
    • doi:10.1016/S0014-5793(04)00356-4
    • JANKNECHT R. On the road to immortality: hTERT upregulation in cancercells. FEBS Lett 2004; 564: 9-13. doi:10.1016/S0014-5793(04)00356-4
    • (2004) FEBS Lett , vol.564 , pp. 9-13
    • Janknecht, R.1
  • 20
    • 33748741642 scopus 로고    scopus 로고
    • Transforming growth factor beta suppresses human telomerase reverse transcriptase (hTERT) by Smad3 interactions with c-Myc and the hTERT gene
    • doi:10.1074/jbc. M602381200
    • LI H, XU D, LI J, BERNDT MC, LIU JP. Transforming growth factor beta suppresses human telomerase reverse transcriptase (hTERT) by Smad3 interactions with c-Myc and the hTERT gene. J Biol Chem 2006; 281: 25588-25600. doi:10.1074/jbc. M602381200
    • (2006) J Biol Chem , vol.281 , pp. 25588-25600
    • Li, H.1    Xu, D.2    Li, J.3    Berndt, M.C.4    Liu, J.P.5
  • 21
    • 33244489807 scopus 로고    scopus 로고
    • Role of Smad3 in the regulation of rat telomerase reverse transcriptase by TGFbeta
    • doi:10.1038/sj.onc.1209140
    • HU B, TACK DC, LIU T, WU Z, ULLENBRUCH MR, et al. Role of Smad3 in the regulation of rat telomerase reverse transcriptase by TGFbeta. Oncogene 2006; 25: 1030-1941. doi:10.1038/sj.onc.1209140
    • (2006) Oncogene , vol.25 , pp. 1030-1941
    • Hu, B.1    Tack, D.C.2    Liu, T.3    Wu, Z.4    Ullenbruch, M.R.5
  • 22
    • 33947225037 scopus 로고    scopus 로고
    • SMAD3 expression is regulated by mitogen-activated protein kinase kinase-1 in epithelial and smooth muscle cells
    • doi:10.1016/j.cellsig.2006.11.008
    • ROSS KR, COREY DA, DUNN JM, KELLEY TJ. SMAD3 expression is regulated by mitogen-activated protein kinase kinase-1 in epithelial and smooth muscle cells. Cell Signal 2007; 19: 923-931. doi:10.1016/j.cellsig.2006.11.008
    • (2007) Cell Signal , vol.19 , pp. 923-931
    • Ross, K.R.1    Corey, D.A.2    Dunn, J.M.3    Kelley, T.J.4
  • 23
    • 49649113170 scopus 로고    scopus 로고
    • Expression of X-linked inhibitor-of-apoptosis protein in hepatocellular carcinoma promotes metastasis and tumor recurrence
    • doi:10.1002/hep.22393
    • SHI YH, DING WX, ZHOU J, HE JY, XU Y, et al. Expression of X-linked inhibitor-of-apoptosis protein in hepatocellular carcinoma promotes metastasis and tumor recurrence. Hepatology 2008; 48: 497-507. doi:10.1002/hep.22393
    • (2008) HepaTology , vol.48 , pp. 497-507
    • Shi, Y.H.1    Ding, W.X.2    Zhou, J.3    He, J.Y.4    Xu, Y.5
  • 24
    • 34548047027 scopus 로고    scopus 로고
    • X-linked inhibitor of apoptosis (XIAP) and XIAP-associated factor-1 expressions and their relationship to apoptosis in human hepatocellular carcinoma and non-cancerous liver tissues
    • SAKEMI R, YANO H, OGASAWARA S, AKIBA J, NAKASHIMA O, et al. X-linked inhibitor of apoptosis (XIAP) and XIAP-associated factor-1 expressions and their relationship to apoptosis in human hepatocellular carcinoma and non-cancerous liver tissues. Oncol Rep 2007; 18: 65-70.
    • (2007) Oncol Rep , vol.18 , pp. 65-70
    • Sakemi, R.1    Yano, H.2    Ogasawara, S.3    Akiba, J.4    Nakashima, O.5
  • 25
    • 34248195931 scopus 로고    scopus 로고
    • Immunohistochemical detection of antiapoptotic protein X-linked inhibitor of apoptosis in mammary carcinoma
    • doi:10.1016/ j.humpath.2006.11.016
    • JAFFER S, ORTA L, SUNKARA S, SABO E, BURSTEIN DE. Immunohistochemical detection of antiapoptotic protein X-linked inhibitor of apoptosis in mammary carcinoma. Hum Pathol 2007; 38: 864-870. doi:10.1016/ j.humpath.2006.11.016
    • (2007) Hum Pathol , vol.38 , pp. 864-870
    • Jaffer, S.1    Orta, L.2    Sunkara, S.3    Sabo, E.4    Burstein, D.E.5
  • 26
    • 1242317030 scopus 로고    scopus 로고
    • Akt phosphorylation and stabilization of X-linked inhibitor of apoptosis protein (XIAP)
    • doi:10.1074/jbc.M312044200
    • DAN HC, SUN M, KANEKO S, FELDMAN RI, NICOSIA SV, et al. Akt phosphorylation and stabilization of X-linked inhibitor of apoptosis protein (XIAP). J Biol Chem 2004; 279: 5405-5412. doi:10.1074/jbc.M312044200
    • (2004) J Biol Chem , vol.279 , pp. 5405-5412
    • Dan, H.C.1    Sun, M.2    Kaneko, S.3    Feldman, R.I.4    Nicosia, S.V.5
  • 27
    • 10744228158 scopus 로고    scopus 로고
    • Regulation and targeting of antiapoptotic XIAP in acute myeloid leukemia
    • doi:10.1038/sj.leu.2403113
    • CARTER BZ, MILELLA M, TSAO T, MCQUEEN T, SCHOBER WD, et al. Regulation and targeting of antiapoptotic XIAP in acute myeloid leukemia. Leukemia 2003; 17: 2081-2089. doi:10.1038/sj.leu.2403113
    • (2003) Leukemia , vol.17 , pp. 2081-2089
    • Carter, B.Z.1    Milella, M.2    Tsao, T.3    McQueen, T.4    Schober, W.D.5
  • 28
    • 58149346113 scopus 로고    scopus 로고
    • Lentiviral-mediated Smad4 RNAi induced anti-proliferation by p16 up-regulation and apoptosis by caspase 3 down-regulation in hepatoma SMMC-7721 cells
    • HUANG S, ZHANG F, MIAO L, ZHANG H, FAN Z, et al. Lentiviral-mediated Smad4 RNAi induced anti-proliferation by p16 up-regulation and apoptosis by caspase 3 down-regulation in hepatoma SMMC-7721 cells. Oncol Rep 2008; 20: 1053-1059.
    • (2008) Oncol Rep , vol.20 , pp. 1053-1059
    • Huang, S.1    Zhang, F.2    Miao, L.3    Zhang, H.4    Fan, Z.5
  • 29
    • 51049117574 scopus 로고    scopus 로고
    • ERK1/2 activation is required for resveratrol-induced apoptosis in MDA-MB-231 cells
    • NGUYEN TH, MUSTAFA FB, PERVAIZ S, NG FS, LIM LH. ERK1/2 activation is required for resveratrol-induced apoptosis in MDA-MB-231 cells. Int J Oncol 2008; 33: 81-92.
    • (2008) Int J Oncol , vol.33 , pp. 81-92
    • Nguyen, T.H.1    Mustafa, F.B.2    Pervaiz, S.3    Ng, F.S.4    Lim, L.H.5
  • 31
    • 58149109602 scopus 로고    scopus 로고
    • GRP78: A chaperone with diverse roles beyond the endoplasmic reticulum
    • QUINONES QJ, DE RIDDER GG, PIZZO SV. GRP78: a chaperone with diverse roles beyond the endoplasmic reticulum. Histol Histopathol 2008; 23: 1409-1416.
    • (2008) Histol Histopathol , vol.23 , pp. 1409-1416
    • Quinones, Q.J.1    de Ridder, G.G.2    Pizzo, S.V.3
  • 32
    • 39149109651 scopus 로고    scopus 로고
    • Etoposide-resistant HT-29 human colon carcinoma cells during glucose deprivation are sensitive to piericidin A, a GRP78 down-regulator
    • doi:10.1002/jcp.21308
    • HWANG JH, KIM JY, CHA MR, RYOO IJ, CHOO SJ, et al. Etoposide-resistant HT-29 human colon carcinoma cells during glucose deprivation are sensitive to piericidin A, a GRP78 down-regulator. J Cell Physiol 2008; 215: 243-250. doi:10.1002/jcp.21308
    • (2008) J Cell Physiol , vol.215 , pp. 243-250
    • Hwang, J.H.1    Kim, J.Y.2    Cha, M.R.3    Ryoo, I.J.4    Choo, S.J.5
  • 33
    • 15044358178 scopus 로고    scopus 로고
    • Expression of stress response protein glucose regulated protein-78 mediated by c-Myb
    • doi:10.1016/ j.biocel.2004.12.011
    • RAMSAY RG, CIZNADIJA D, MANTAMADIOTIS T, ANDERSON R, PEARSON R. Expression of stress response protein glucose regulated protein-78 mediated by c-Myb. Int J Biochem Cell Biol 2005; 37: 1254-1268. doi:10.1016/ j.biocel.2004.12.011
    • (2005) Int J Biochem Cell Biol , vol.37 , pp. 1254-1268
    • Ramsay, R.G.1    Ciznadija, D.2    Mantamadiotis, T.3    Anderson, R.4    Pearson, R.5
  • 34
    • 33749565607 scopus 로고    scopus 로고
    • Effect of selected insecticides on growth rate and stress protein expression in cultured human A549 and SH-SY5Y cells
    • doi:10.1016/j.tiv.2006.06.001
    • SKANDRANI D, GAUBIN Y, BEAU B, MURAT JC, VINCENT C, et al. Effect of selected insecticides on growth rate and stress protein expression in cultured human A549 and SH-SY5Y cells. Toxicol In Vitro 2006; 20: 1378-1386. doi:10.1016/j.tiv.2006.06.001
    • (2006) Toxicol In Vitro , vol.20 , pp. 1378-1386
    • Skandrani, D.1    Gaubin, Y.2    Beau, B.3    Murat, J.C.4    Vincent, C.5
  • 35
    • 62149130352 scopus 로고    scopus 로고
    • P-Cadherin and beta-catenin are useful prognostic markers in breast cancer patients; beta-catenin interacts with heat shock protein Hsp27
    • doi:10.1007/s12192-007-0007-z
    • FANELLI MA, MONTT-GUEVARA M, DIBLASI AM, GAGO FE, TELLO O, et al. P-Cadherin and beta-catenin are useful prognostic markers in breast cancer patients; beta-catenin interacts with heat shock protein Hsp27. Cell Stress Chaperones 2008; 13: 207-220. doi:10.1007/s12192-007-0007-z
    • (2008) Cell Stress Chaperones , vol.13 , pp. 207-220
    • Fanelli, M.A.1    Montt-Guevara, M.2    Diblasi, A.M.3    Gago, F.E.4    Tello, O.5
  • 36
    • 27944473690 scopus 로고    scopus 로고
    • VEGF as a key mediator of angiogenesis in cancer
    • doi:10.1159/000088478
    • CARMELIET P. VEGF as a key mediator of angiogenesis in cancer. Oncology 2005; 69: 4-10. doi:10.1159/000088478
    • (2005) Oncology , vol.69 , pp. 4-10
    • Carmeliet, P.1
  • 37
    • 41649100471 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase kinase signaling promotes growth and vascularization of fibrosarcoma
    • doi:10.1158/1535-7163. MCT-07-2229
    • DING Y, BOGUSLAWSKI EA, BERGHUIS BD, YOUNG JJ, ZHANG Z, et al. Mitogen-activated protein kinase kinase signaling promotes growth and vascularization of fibrosarcoma. Mol Cancer Ther 2008; 7: 648-658. doi:10.1158/1535-7163. MCT-07-2229
    • (2008) Mol Cancer Ther , vol.7 , pp. 648-658
    • Ding, Y.1    Boguslawski, E.A.2    Berghuis, B.D.3    Young, J.J.4    Zhang, Z.5
  • 38
    • 34249722245 scopus 로고    scopus 로고
    • STAT3 mediates bone marrow mesenchymal stem cell VEGF production
    • doi:10.1016/j.yjmcc.2007.04.010
    • WANG M, ZHANG W, CRISOSOMO P, MARKEL T, MELDRUM KK, et al. STAT3 mediates bone marrow mesenchymal stem cell VEGF production. J Mol Cell Cardiol 2007; 42: 1009-1015. doi:10.1016/j.yjmcc.2007.04.010
    • (2007) J Mol Cell Cardiol , vol.42 , pp. 1009-1015
    • Wang, M.1    Zhang, W.2    Crisosomo, P.3    Markel, T.4    Meldrum, K.K.5
  • 39
    • 39449115697 scopus 로고    scopus 로고
    • Androgen receptor and invasion in prostate cancer
    • doi:10.1158/0008-5472.CAN-07-1929
    • HARA T, MIYAZAKI H, LEE A, TRAN CP, REITER RE. Androgen receptor and invasion in prostate cancer. Cancer Res 2008; 68: 1128-1135. doi:10.1158/0008-5472.CAN-07-1929
    • (2008) Cancer Res , vol.68 , pp. 1128-1135
    • Hara, T.1    Miyazaki, H.2    Lee, A.3    Tran, C.P.4    Reiter, R.E.5
  • 40
    • 66849102370 scopus 로고    scopus 로고
    • Interleukin-6 Mediates G(0)/G(1) Growth Arrest in Hepatocellular Carcinoma through a STAT3-Dependent Pathway
    • Epub ahead of print.
    • MORAN DM, MATTOCKS MA, CAHILL PA, KONIARIS LG, MCKILLOP IH. Interleukin-6 Mediates G(0)/G(1) Growth Arrest in Hepatocellular Carcinoma through a STAT3-Dependent Pathway. J Surg Res 2007; 13; Epub ahead of print.
    • (2007) J Surg Res , vol.13
    • Moran, D.M.1    Mattocks, M.A.2    Cahill, P.A.3    Koniaris, L.G.4    McKillop, I.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.