Human leukocyte antigen class II and type 1 diabetes in Latin America: A combined meta-analysis of association and family-based studies

Human Immunology

Volumn 72, Issue 7, 2011, Pages 581-586

  Cifuentes, Ricardo A ^a   Rojas Villarraga, Adriana ^a   Anaya, Juan Manuel ^a  

^a UNIVERSIDAD DEL ROSARIO   (Colombia)

Author keywords

Autoimmunity; HLA class II; Latin America; Meta analysis; Type 1 diabetes

Indexed keywords

HLA ANTIGEN CLASS 2; HLA DQB1 ANTIGEN; HLA DR ANTIGEN;

ARTICLE; CAUCASIAN; DIABETOGENESIS; ETHNICITY; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC RISK; HAPLOTYPE; HISPANIC; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; META ANALYSIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION;

ALLELES; AMINO ACID SEQUENCE; COMPUTATIONAL BIOLOGY; DIABETES MELLITUS, TYPE 1; EPITOPES; HAPLOTYPES; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; LATIN AMERICA; PEPTIDES; PROTEIN BINDING;

EID: 79958271443     PISSN: 01988859     EISSN: 18791166     Source Type: Journal    
DOI: 10.1016/j.humimm.2011.03.012     Document Type: Article

References (30)

1. Gorodezky C., Alaez C., Murguia A., Rodriguez A., Balladares S., Vazquez M., et al. HLA and autoimmune diseases: Type 1 diabetes (T1D) as an example. Autoimmun Rev 2006, 5:187-194.
2. Davies J.L., Kawaguchi Y., Bennett S.T., Copeman J.B., Cordell H.J., Pritchard L.E., et al. A genome-wide search for human type 1 diabetes susceptibility genes. Nature 1994, 371:130-136.
3. Concannon P., Erlich H.A., Julier C., Morahan G., Nerup J., Pociot F., et al. Type 1 diabetes: Evidence for susceptibility loci from four genome-wide linkage scans in 1,435 multiplex families. Diabetes 2005, 54:2995-3001.
4. Todd J.A., Bell J.I., McDevitt H.O. HLA DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus. Nature 1987, 329:599-604.
5. Koeleman B.P., Lie B.A., Undlien D.E., Dudbridge F., Thorsby E., de Vries R.R., et al. Genotype effects and epistasis in type 1 diabetes and HLA-DQ trans dimer associations with disease. Genes Immun 2004, 5:381-388.
6. Erlich H., Valdes A.M., Noble J., Carlson J.A., Varney M., Concannon P., et al. HLA DR-DQ haplotypes and genotypes and type 1 diabetes risk: Analysis of the type 1 diabetes genetics consortium families. Diabetes 2008, 57:1084-1092.
7. Mehers K.L., Gillespie K.M. The genetic basis for type 1 diabetes. Br Med Bull 2008, 88:115-129.
8. Incidence and trends of childhood type 1 diabetes worldwide 1990-1999. Diabet Med 2006, 23:857-866. DIAMOND Project Group.
9. Thomson G., Valdes A.M., Noble J.A., Kockum I., Grote M.N., Najman J., et al. Relative predispositional effects of HLA class II DRB1-DQB1 haplotypes and genotypes on type 1 diabetes: A meta-analysis. Tissue Antigens 2007, 70:110-127.
10. Salzano F.M. Interethnic variability and admixture in Latin America-social implications. Rev Biol Trop 2004, 52:405-415.
11. Serrano-Rios M., Goday A., Martinez Larrad T. Migrant populations and the incidence of type 1 diabetes mellitus: An overview of the literature with a focus on the Spanish-heritage countries in Latin America. Diabetes Metab Res Rev 1999, 15:113-132.
12. Valdes A.M., McWeeney S., Thomson G. HLA class II DR-DQ amino acids and insulin-dependent diabetes mellitus: Application of the haplotype method. Am J Hum Genet 1997, 60:717-728.
13. Nicodemus K.K., Catmap Case-control and TDT meta-analysis package. BMC Bioinformatics 2008, 9:130.
14. Kazeem G.R., Farrall M. Integrating case-control and TDT studies. Ann Hum Genet 2005, 69:329-335.
15. Koskinen L.L., Einarsdottir E., Dukes E., Heap G.A., Dubois P., Korponay-Szabo I.R., et al. Association study of the IL18RAP locus in three European populations with coeliac disease. Hum Mol Genet 2009, 18:1148-1155.
16. Huedo-Medina T.B., Sanchez-Meca J., Marin-Martinez F., Botella J. Assessing heterogeneity in meta-analysis: Q statistic or I2 index?. Psychol Methods 2006, 11:193-206.
17. Spielman R.S., McGinnis R.E., Ewens W.J. Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet 1993, 52:506-516.
18. Rojas-Villarraga A., Botello-Corzo D., Anaya J.M. HLA-Class II in Latin American patients with type 1 diabetes. Autoimmun Rev 2010, 9:666-673.
19. Wang P., Sidney J., Dow C., Mothe B., Sette A., Peters B., et al. A systematic assessment of MHC class II peptide binding predictions and evaluation of a consensus approach. PLoS Comput Biol 2008, 4;:e1000048.
20. Gorodezky C., Olivo A., Alaez C., Vazquez M.N., de la Rosa G., Debaz H., et al. High- and low-risk molecular sequences in autoimmune diseases. An analysis of type I diabetes in Latin America. Gac Med Mex 1997, 133(Suppl 1):125-132.
21. Pugliese A. Genetics of type 1 diabetes. Endocrinol Metab Clin North Am 2004, 33:1-16.
22. Rewers A., Babu S., Wang T.B., Bugawan T.L., Barriga K., Eisenbarth G.S., et al. Ethnic differences in the associations between the HLA-DRB1*04 subtypes and type 1 diabetes. Ann N Y Acad Sci 2003, 1005:301-309.
23. Yasunaga S., Kimura A., Hamaguchi K., Ronningen K.S., Sasazuki T. Different contribution of HLA-DR and -DQ genes in susceptibility and resistance to insulin-dependent diabetes mellitus (IDDM). Tissue Antigens 1996, 47:37-48.
24. Pugliese A., Kawasaki E., Zeller M., Yu L., Babu S., Solimena M., et al. Sequence analysis of the diabetes-protective human leukocyte antigen-DQB1*0602 allele in unaffected, islet cell antibody-positive first degree relatives and in rare patients with type 1 diabetes. J Clin Endocrinol Metab 1999, 84:1722-1728.
25. Erlich H.A., Zeidler A., Chang J., Shaw S., Raffel L.J., Klitz W., et al. HLA class II alleles and susceptibility and resistance to insulin dependent diabetes mellitus in Mexican-American families. Nat Genet 1993, 3:358-364.
26. Qu H.Q., Marchand L., Szymborski A., Grabs R., Polychronakos C. The association between type 1 diabetes and the ITPR3 gene polymorphism due to linkage disequilibrium with HLA class II. Genes Immun 2008, 9:264-266.
27. Cheung Y.H., Watkinson J., Anastassiou D. Conditional meta-analysis stratifying on detailed HLA genotypes identifies a novel type 1 diabetes locus around TCF19 in the MHC. Hum Genet 2011, 129:161-176.
28. Ge X., James E.A., Reijonen H., Kwok W.W. Differences in self-peptide binding between T1D-related susceptible and protective DR4 subtypes. J Autoimmun 2011, 36:155-160.
29. Chang K.Y., Unanue E.R. Prediction of HLA-DQ8beta cell peptidome using a computational program and its relationship to autoreactive T cells. Int Immunol 2009, 21:705-713.
30. Di Lorenzo T.P., Peakman M., Roep B.O. Translational mini-review series on type 1 diabetes: Systematic analysis of T-cell epitopes in autoimmune diabetes. Clin Exp Immunol 2007, 148:1-16.