Transgenic mice overexpressing the extracellular domain of NCAM are impaired in working memory and cortical plasticity

Neurobiology of Disease

Volumn 43, Issue 2, 2011, Pages 372-378

  Brennaman, Leann H ^a   Kochlamazashvili, Gaga ^b   Stoenica, Luminita ^c   Nonneman, Randall J ^a   Moy, Sheryl S ^a   Schachner, Melitta ^c,d   Dityatev, Alexander ^b,c   Maness, Patricia F ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

^c UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^d RUTGERS UNIVERSITY   (United States)

Author keywords

LTP; NCAM; Neuropsychiatric disorders; Prefrontal cortex; STP; Synaptic plasticity; Working memory

Indexed keywords

NERVE CELL ADHESION MOLECULE;

ANIMAL CELL; ANIMAL TISSUE; ANXIETY; ARTICLE; BEHAVIOR; BRAIN FUNCTION; COGNITION; CONTROLLED STUDY; CORTICAL AMYGDALA; ELECTROPHYSIOLOGY; EXCITATORY POSTSYNAPTIC POTENTIAL; FEMALE; GENE OVEREXPRESSION; HIPPOCAMPUS; LONG TERM POTENTIATION; MALE; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN DOMAIN; SMELLING; SOCIAL STATUS; SYMPATHETIC INNERVATION; SYNAPSE; SYNAPTIC TRANSMISSION; WORKING MEMORY;

ANIMALS; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; EXTRACELLULAR SPACE; FEMALE; MALE; MEMORY DISORDERS; MEMORY, SHORT-TERM; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEURAL CELL ADHESION MOLECULES; NEURONAL PLASTICITY; NEURONS; ORGAN CULTURE TECHNIQUES; PROTEIN STRUCTURE, TERTIARY; PROTEOLYSIS;

EID: 79958240859     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2011.04.008     Document Type: Article

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