Meta-analysis of randomized intra-arterial thrombolytic trials for the treatment of acute stroke due to middle cerebral artery occlusion

Journal of NeuroInterventional Surgery

Volumn 3, Issue 2, 2011, Pages 151-155

  Fields, Jeremy D ^a   Khatri, Pooja ^b   Nesbit, Gary M ^a   Liu, Kenneth C ^c   Barnwell, Stanley L ^a   Lutsep, Helmi L ^a   Clark, Wayne M ^a   Lansberg, Maarten G ^d  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^d STANFORD UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRINOLYTIC AGENT; HEPARIN; PLACEBO; UROKINASE;

ADULT; AGED; ARTICLE; BRAIN HEMORRHAGE; CEREBROVASCULAR ACCIDENT; CLINICAL ASSESSMENT; CONTROLLED STUDY; DISEASE ASSOCIATION; DOSE RESPONSE; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG MEGADOSE; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; META ANALYSIS; MIDDLE CEREBRAL ARTERY OCCLUSION; MORTALITY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RANKIN SCALE; RISK FACTOR; TREATMENT RESPONSE;

FIBRINOLYTIC AGENTS; HUMANS; INFARCTION, MIDDLE CEREBRAL ARTERY; INFUSIONS, INTRA-ARTERIAL; RANDOMIZED CONTROLLED TRIALS AS TOPIC; THROMBOLYTIC THERAPY;

EID: 79958225957     PISSN: 17598478     EISSN: 17598486     Source Type: Journal    
DOI: 10.1136/jnis.2010.002766     Document Type: Article

References (17)

1. Suzuki S, Saver JL, Scott P, et al. Access to intra-arterial therapies for acute ischemic stroke: an analysis of the US population. AJNR Am J Neuroradiol 2004;25:1802-6. (Pubitemid 44123711)
2. Furlan A, Higashida R, Wechsler L, et al. Intra-arterial prourokinase for acute ischemic stroke. The PROACT II study: a randomized controlled trial. Prolyse in Acute Cerebral Thromboembolism. JAMA 1999;282:2003-11.
3. Ogawa A, Mori E, Minematsu K, et al. Randomized trial of intraarterial infusion of urokinase within 6 hours of middle cerebral artery stroke: the middle cerebral artery embolism local fibrinolytic intervention trial (MELT) Japan. Stroke 2007;38:2633-9. (Pubitemid 47493996)
4. Smith WS, Lev MH, English JD, et al. Significance of large vessel intracranial occlusion causing acute ischemic stroke and TIA. Stroke 2009;40:3834-40.
5. del Zoppo GJ, Higashida RT, Furlan AJ, et al. PROACT: a phase II randomized trial of recombinant pro-urokinase by direct arterial delivery in acute middle cerebral artery stroke. PROACT Investigators. Prolyse in Acute Cerebral Thromboembolism. Stroke 1998;29:4-11.
6. Higgins JPT, Green S, eds. Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.2. Oxford, UK: The Cochrane Collaboration, 2009.
7. Rha JH, Saver JL. The impact of recanalization on ischemic stroke outcome: a metaanalysis. Stroke 2007;38:967-73. (Pubitemid 46568460)
8. Saver JL, Gornbein J. Treatment effects for which shift or binary analyses are advantageous in acute stroke trials. Neurology 2009;72:1310-15.
9. Stead LG, Gilmore RM, Bellolio MF, et al. Percutaneous clot removal devices in acute ischemic stroke: a systematic review and meta-analysis. Arch Neurol 2008;65:1024-30.
10. Macleod MR, Davis SM, Mitchell PJ, et al. Results of a multicentre, randomised controlled trial of intra-arterial urokinase in the treatment of acute posterior circulation ischaemic stroke. Cerebrovasc Dis 2005;20:12-17. (Pubitemid 41003629)
11. Keris V, Rudnicka S, Vorona V, et al. Combined intraarterial/intravenous thrombolysis for acute ischemic stroke. AJNR Am J Neuroradiol 2001;22:352-8. (Pubitemid 32163468)
12. Lee M, Hong KS, Saver JL. Efficacy of intra-arterial fibrinolysis for acute ischemic stroke: meta-analysis of randomized controlled trials. Stroke 2010;41:932-7.
13. Saver JL. Intra-arterial fibrinolysis for acute ischemic stroke: the message of melt. Stroke 2007;38:2627-8. (Pubitemid 47493993)
14. Wardlaw JM, Murray V, Berge E, et al. Thrombolysis for acute ischaemic stroke. Cochrane Database Syst Rev 2009;4:CD000213.
15. Smith WS. Intra-arterial thrombolytic therapy for acute basilar occlusion: pro. Stroke 2007;38:701-3. (Pubitemid 46188250)
16. Nogueira RG, Yoo AJ, Buonanno FS, et al. Endovascular approaches to acute stroke, part 2: a comprehensive review of studies and trials. AJNR Am J Neuroradiol 2009;30:859-75.
17. Adams HP Jr, del Zoppo G, Alberts MJ, et al. Guidelines for the early management of adults with ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: The American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists. Circulation 2007;115:e478-534.