Proton therapy: Clinical gains through current and future treatment programs

Frontiers of Radiation Therapy and Oncology

Volumn 43, Issue , 2011, Pages 440-464

  Mohan, Radhe ^a   Bortfeld, Thomas ^b  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COBALT 60; PROTON;

ALGORITHM; ARTICLE; CLINICAL PRACTICE; COBALT THERAPY; COMPUTER ASSISTED EMISSION TOMOGRAPHY; COMPUTER ASSISTED RADIOTHERAPY; DOSIMETRY; EXPERIMENTAL STUDY; HUMAN; IMAGE ANALYSIS; INTENSITY MODULATED RADIATION THERAPY; LINEAR ACCELERATOR; MEDICAL RESEARCH; MONTE CARLO METHOD; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRACTICE GUIDELINE; PRIORITY JOURNAL; PROTON RADIATION; PROTON THERAPY; RADIATION DOSE DISTRIBUTION; RADIATION DOSE FRACTIONATION; RADIATION SCATTERING; RADIOBIOLOGY; SYNCHROTRON; TOMOTHERAPY; TREATMENT PLANNING;

HUMANS; NEOPLASMS; PROTONS; RADIATION ONCOLOGY; RADIOTHERAPY;

DOSIMETRY; PROTON BEAMS; TISSUE;

ADAPTIVE RADIOTHERAPY; CLINICAL EFFICIENCY; COMPUTATION ALGORITHM; INTENSITY MODULATIONS; PHYSICAL CHARACTERISTICS; PROTON DOSIMETRIES; TECHNICAL IMPROVEMENT; TREATMENT PLANNING;

PROTON BEAM THERAPY;

EID: 79958209727     PISSN: 00719676     EISSN: 16623789     Source Type: Book Series    
DOI: 10.1159/000322509     Document Type: Article

References (22)

1. ICRU Report 50: Prescribing, Recording, and Reporting Photon Beam Therapy. Bethesda, International Commission on Radiation Units and Measurements, 1993.
2. ICRU Report 62: Prescribing, Recording and Reporting Photon Beam Therapy (supplement to ICRU report 50). Bethesda, International Commission on Radiation Units and Measurements, 1999.
3. Urie M, Goitein M, Wagner M: Compensating for heterogeneities in proton radiation therapy. Phys Med Biol 1984; 29: 553-566. (Pubitemid 14054632)
4. Kang Y, Zhang X, Chang JY, Wang H, Wei X, Liao Z, Komaki R, Cox JD, Balter PA, Liu H, Zhu SR, Mohan R, Dong L: 4D proton treatment planning strategy for mobile lung tumors. Int J Radiat Oncol Biol Phys 2007; 67: 906-914. (Pubitemid 46215899)
5. Engelsman M, Rietzel E, Kooy HM: Four-dimensional proton treatment planning for lung tumors. Int J Radiat Oncol Biol Phys 2006; 4: 1589-1595.
6. Goitein M: Calculation of the uncertainty in the dose delivered during radiation therapy. Med Phys 1985; 12: 608-612. (Pubitemid 15248417)
7. Trofimov A, Bortfeld T: Optimization of Beam Parameters and Treatment Planning for Intensity Modulated Proton Therapy. Technol Cancer Res Treat 2003; 2: 437-444. (Pubitemid 37363000)
8. Hall E: Intensity-modulated radiation therapy, protons, and the risk of second cancers. Int J Radiat Oncol Biol Phys 2006; 65: 1-7.
9. Kooy H, Clasie BM, Lu H-M, et al: A case study in proton pencil-beam scanning delivery. Int J Radiat Oncol Biol Phys 2010; 76: 624-630.
10. Pedroni E, Bacher R, Blattmann H, et al: The 200- MeV proton therapy project at the Paul Scherrer Institute: conceptual design and practical realization. Med Phys 1995; 22: 37-53.
11. Phillips MH, Pedroni E, Blattmann H, Boehringer T, Coray A, Scheib S: Effects of respiratory motion on dose uniformity with a charged particle scanning method. Phys Med Biol 1992; 7: 223-234.
12. Bortfeld T, Jokivarsi K, Goitein M, Kung J, Jiang SB: Effects of intra-fraction motion on IMRT dose delivery: statistical analysis and simulation. Phys Med Biol 2002; 47: 2203-20. (Pubitemid 34812201)
13. Bert C, Saito N, Schmidt A, Chaudhri N, Schardt D, Rietzel E: Target motion tracking with a scanned particle beam, target motion tracking with a scanned particle beam. Med Phys 2007; 34: 4768-4771.
14. Lomax J, Boehringer T, Coray A, et al: Intensity modulated proton therapy: a clinical example. Med Phys 2001; 28: 317-324. (Pubitemid 32231687)
15. Unkelbach J, Bortfeld T, Martin BC, Soukup M: Reducing the sensitivity of IMPT treatment plans to setup errors and range uncertainties via probabilistic treatment planning. Med Phys 2009; 36: 149-163.
16. Oelfke U, Lam GKY, Atkins MS: Proton dose monitoring with PET: quantitative studies in Lucite. Phys Med Biol 1996; 41: 177-196. (Pubitemid 26034231)
17. Parodi K, Paganetti H, Shih HA, Michaud S, Loeffler JS, DeLaney TF, Liebsch NJ, Munzenrider JE, Fischman AJ, Knopf A, Bortfeld T: Patient study of in vivo verification of beam delivery and range, using positron emission tomography and computed tomography imaging after proton therapy. Int J Radiat Oncol Biol Phys 2007; 68: 920-934. (Pubitemid 46818759)
18. Min C-H, Kim CH, Youn M-Y, Kim J-W: Prompt gamma measurements for locating the dose falloff region in the proton therapy. Appl Phys Lett 2006; 89: 183517.
19. Polf JC, Peterson S, Ciangaru G, Gillin M, Beddar S: Prompt gamma-ray emission from biological tissues during proton irradiation: a preliminary study. Phys Med Biol 2009; 54: 731-743.
20. Krejcarek SC, Grant PE, Henson JW, et al: Physiologic and radiographic evidence of the distal edge of the proton beam in craniospinal irradiation. Int J Radiat Oncol Biol Phys 2007; 68: 646-649. (Pubitemid 46818750)
21. Gensheimer MF, Yock TI, Liebsch NJ, Sharp GC, Paganetti H, Madan N, Grant PE, Bortfeld T: In vivo proton beam range verification using spine MRI changes. Int J Radiat Oncol Biol Phys 2010; 78: 268-275.
22. Schwoerer H, Pfotenhauer S, Jäckel O, Amthor K-U, Liesfeld B, Ziegler W, Sauerbrey R, Ledingham KWD, Esirkepov T: Laser-plasma acceleration of quasi-monoenergetic protons from microstructured targets. Nature 2006; 439: 445-448. (Pubitemid 43152831)