Early occurrence of lung adenocarcinoma and breast cancer after radiotherapy of a chest wall sarcoma in a patient with a de novo germline mutation in TP53

Familial Cancer

Volumn 10, Issue 2, 2011, Pages 187-192

  Ferrarini, Alessandra ^a   Auteri Kaczmarek, Agnes ^a   Pica, Alessia ^a   Boesch, Nemya ^b   Heinimann, Karl ^b   Schäfer, Stephan C ^a   Vesnaver Megalo, Sara ^a   Cina, Viviane ^a   Beckmann, Jacques S ^a   Monnerat, Christian ^a  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

Author keywords

De novo mutation; Germline mutation TP53; Li Fraumeni syndrome; p.Arg213X

Indexed keywords

ANTINEOPLASTIC AGENT; CARBOPLATIN; DOCETAXEL; GENOMIC DNA; PROTEIN P53; TRASTUZUMAB;

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER ADJUVANT THERAPY; CANCER RADIOTHERAPY; CASE REPORT; COLON CANCER; DISEASE COURSE; DNA SEQUENCE; EARLY CANCER; EXON; FAMILIAL CANCER; FEMALE; GALLBLADDER CANCER; GENE MUTATION; GENETIC SCREENING; GERM LINE; HUMAN; HUMAN TISSUE; INTRADUCTAL CARCINOMA; JAW CANCER; JAW OSTEOSARCOMA; LUNG ADENOCARCINOMA; LUNG ALVEOLUS CELL CARCINOMA; LUNG NODULE; LYMPH NODE DISSECTION; MASTECTOMY; MULTIPLE CYCLE TREATMENT; NONSENSE MUTATION; PEDIGREE ANALYSIS; PHENOTYPE; PRIORITY JOURNAL; THORAX WALL CANCER; THORAX WALL SARCOMA; TUMOR BIOPSY;

ADENOCARCINOMA; ADULT; BREAST NEOPLASMS; FEMALE; GERM-LINE MUTATION; HUMANS; LUNG NEOPLASMS; NEOPLASMS, SECOND PRIMARY; SARCOMA; THORACIC NEOPLASMS; THORACIC WALL; TUMOR SUPPRESSOR PROTEIN P53;

EID: 79958169763     PISSN: 13899600     EISSN: 15737292     Source Type: Journal    
DOI: 10.1007/s10689-010-9415-9     Document Type: Article

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