Antidepressant response in major depressive disorder: A meta-regression comparison of randomized controlled trials and observational studies

PLoS ONE

Volumn 6, Issue 6, 2011, Pages

  Naudet, Florian ^a,b,c   Maria, Anne Solène ^a,d   Falissard, Bruno ^a,e,f  

^a INSERM   (France)

^b UNIVERSITÉ DE RENNES 1   (France)

^c RENNES UNIVERSITY HOSPITAL   (France)

^d Ecole de Psychologues Praticiens   (France)

^e UNIVERSITÉ PARIS DESCARTES   (France)

^f HÔPITAL PAUL BROUSSE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

FLUOXETINE; PLACEBO; VENLAFAXINE; ANTIDEPRESSANT AGENT;

ANXIETY; DRUG MEGADOSE; DYSTHYMIA; HAMILTON SCALE; HOSPITAL PATIENT; HUMAN; LOW DRUG DOSE; MAJOR DEPRESSION; META ANALYSIS; MONTGOMERY ASBERG DEPRESSION RATING SCALE; OBSERVATIONAL STUDY; OUTCOME ASSESSMENT; OUTPATIENT; RANDOMIZED CONTROLLED TRIAL (TOPIC); REGRESSION ANALYSIS; REVIEW; STANDARDIZATION; SYSTEMATIC REVIEW; TREATMENT RESPONSE; ARTICLE; COMPARATIVE STUDY; EPIDEMIOLOGY; TREATMENT OUTCOME;

ANTIDEPRESSIVE AGENTS; BIAS (EPIDEMIOLOGY); DEPRESSIVE DISORDER, MAJOR; HUMANS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; REGRESSION ANALYSIS; TREATMENT OUTCOME;

EID: 79958167513     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0020811     Document Type: Review

References (42)

1. Turner EH, Matthews AM, Linardatos E, Tell RA, Rosenthal R, (2008) Selective publication of antidepressant trials and its influence on apparent efficacy. N Engl J Med 358: 252-260.
2. Fournier JC, DeRubeis RJ, Hollon SD, Dimidjian S, Amsterdam JD, et al. (2010) Antidepressant drug effects and depression severity: a patient-level meta-analysis. Jama 303: 47-53.
3. Kirsch I, Deacon BJ, Huedo-Medina TB, Scoboria A, Moore TJ, et al. (2008) Initial severity and antidepressant benefits: a meta-analysis of data submitted to the Food and Drug Administration. PLoS Med 5: e45.
4. Walsh BT, Seidman SN, Sysko R, Gould M, (2002) Placebo response in studies of major depression: variable, substantial, and growing. Jama 287: 1840-1847.
5. Posternak MA, Zimmerman M, (2007) Therapeutic effect of follow-up assessments on antidepressant and placebo response rates in antidepressant efficacy trials: meta-analysis. Br J Psychiatry 190: 287-292.
6. Papakostas GI, Fava M, (2009) Does the probability of receiving placebo influence clinical trial outcome? A meta-regression of double-blind, randomized clinical trials in MDD. Eur Neuropsychopharmacol 19: 34-40.
7. Bialik RJ, Ravindran AV, Bakish D, Lapierre YD, (1995) A comparison of placebo responders and nonresponders in subgroups of depressive disorder. J Psychiatry Neurosci 20: 265-270.
8. Trivedi MH, Rush H, (1994) Does a placebo run-in or a placebo treatment cell affect the efficacy of antidepressant medications? Neuropsychopharmacology 11: 33-43.
9. Zimmerman M, Chelminski I, Posternak MA, (2005) Generalizability of antidepressant efficacy trials: differences between depressed psychiatric outpatients who would or would not qualify for an efficacy trial. Am J Psychiatry 162: 1370-1372.
10. Wisniewski SR, Rush AJ, Nierenberg AA, Gaynes BN, Warden D, et al. (2009) Can phase III trial results of antidepressant medications be generalized to clinical practice? A STAR*D report. Am J Psychiatry 166: 599-607.
11. Wei L, Ebrahim S, Bartlett C, Davey PD, Sullivan FM, et al. (2005) Statin use in the secondary prevention of coronary heart disease in primary care: cohort study and comparison of inclusion and outcome with patients in randomised trials. Bmj 330: 821.
12. Leichsenring F, Rabung S, (2008) Effectiveness of long-term psychodynamic psychotherapy: a meta-analysis. Jama 300: 1551-1565.
13. Drugs Information Online website. Available: http://www.drugs.com/top200.html Accessed 2011 May 14.
14. The Joanna Briggs Institute (2008) Joanna Briggs Institute Reviewers' Manual: 2008 edition Adelaide: The Joanna Briggs Institute. Available: http://www.joannabriggs.edu.au/Documents/JBIReviewManual_CiP11449.pdf/ Accessed 26 April 2011.
15. Higgins JPT, Green S, (2008) Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.2. Available: http://www.cochrane-handbook.org/ Accessed 2009 November 26.
16. Cipriani A, Furukawa TA, Salanti G, Geddes JR, Higgins JP, et al. (2009) Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis. Lancet 373: 746-758.
17. Greenland S, Maclure M, Schlesselman JJ, Poole C, Morgenstern H, (1991) Standardized regression coefficients: a further critique and review of some alternatives. Epidemiology 2: 387-392.
18. Greenland S, Schlesselman JJ, Criqui MH, (1986) The fallacy of employing standardized regression coefficients and correlations as measures of effect. Am J Epidemiol 123: 203-208.
19. Hedges L, Olkin I, (1985) Statistical Methods for Meta-analysis New York, NY Academic Press.
20. Little RJA, Rubin DB, eds. (1987) Statistical analysis with missing data Wiley & Sons, New York.
21. Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gotzsche PC, et al. (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. PLoS Med 6: e1000100.
22. Stroup DF, Berlin JA, Morton SC, Olkin I, Williamson GD, et al. (2000) Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. Jama 283: 2008-2012.
23. De Jonghe F, Dekker J, (1999) Early symptomatic changes in patients with major depression treated with antidepressants. The European journal of psychiatry 13: 69-76.
24. Simon GE, VonKorff M, Heiligenstein JH, Revicki DA, Grothaus L, et al. (1996) Initial antidepressant choice in primary care. Effectiveness and cost of fluoxetine vs tricyclic antidepressants. JAMA: the journal of the American Medical Association 275: 1897-1902.
25. Bauer M, Tharmanathan P, Volz HP, Moeller HJ, Freemantle N, (2009) The effect of venlafaxine compared with other antidepressants and placebo in the treatment of major depression: a meta-analysis. Eur Arch Psychiatry Clin Neurosci 259: 172-185.
26. Vandenbroucke JP, (2004) When are observational studies as credible as randomised trials? Lancet 363: 1728-1731.
27. Falissard B, Izard V, Xerri B, Bouvenot G, Meyer F, et al. (2010) Relative effectiveness assessment of listed drugs (REAL): a new method for an early comparison of the effectiveness of approved health technologies. Int J Technol Assess Health Care 26: 124-130.
28. Emanuel EJ, Miller FG, (2001) The ethics of placebo-controlled trials-a middle ground. N Engl J Med 345: 915-919.
29. Perlis RH, Ostacher M, Fava M, Nierenberg AA, Sachs GS, et al. (2010) Assuring That Double-Blind Is Blind. Am J Psychiatry 167: 250-252.
30. Posternak MA, Zimmerman M, Keitner GI, Miller IW, (2002) A reevaluation of the exclusion criteria used in antidepressant efficacy trials. Am J Psychiatry 159: 191-200.
31. Bluhm R, (2009) Some observations on observational research. Perspect Biol Med 52: 252-263.
32. Concato J, (2004) Observational versus experimental studies: what's the evidence for a hierarchy? Neuro Rx 1: 341-347.
33. Lawlor DA, Davey Smith G, Bruckdorfer KR, Kundu D, Ebrahim S, (2004) Observational versus randomised trial evidence. Lancet 364: 755.
34. Seemuller F, Moller HJ, Obermeier M, Adli M, Bauer M, et al. (2010) Do efficacy and effectiveness samples differ in antidepressant treatment outcome? An analysis of eligibility criteria in randomized controlled trials. J Clin Psychiatry 71: 1425-1433.
35. National Institute for Clinical Excellence (2004) Depression: management of depression in primary and secondary care. Clinical practice guideline No 23 London NICE;2004.
36. Ioannidis JP, (2008) Effectiveness of antidepressants: an evidence myth constructed from a thousand randomized trials? Philos Ethics Humanit Med 3: 14.
37. Egger M, Smith GD, Sterne JA, (2001) Uses and abuses of meta-analysis. Clin Med 1: 478-484.
38. Thompson SG, Higgins JP, (2005) Treating individuals 4: can meta-analysis help target interventions at individuals most likely to benefit? Lancet 365: 341-346.
39. Thompson SG, Higgins JP, (2002) How should meta-regression analyses be undertaken and interpreted? Stat Med 21: 1559-1573.
40. Ma J, Liu W, Hunter A, Zhang W, (2008) Performing meta-analysis with incomplete statistical information in clinical trials. BMC Med Res Methodol 8: 56.
41. Nakajima S, Suzuki T, Watanabe K, Kashima H, Uchida H, (2010) Accelerating response to antidepressant treatment in depression: a review and clinical suggestions. Prog Neuropsychopharmacol Biol Psychiatry 34: 259-264.
42. Vandenbroucke JP, Psaty BM, (2008) Benefits and risks of drug treatments: how to combine the best evidence on benefits with the best data about adverse effects. Jama 300: 2417-2419.