Formation and properties of magnesium-ammonium-phosphate hexahydrate biocements in the Ca-Mg-PO4 system

Journal of Materials Science: Materials in Medicine

Volumn 22, Issue 3, 2011, Pages 429-436

  Vorndran, Elke ^a   Ewald, Andrea ^a   Müller, Frank A ^b   Zorn, Katharina ^b   Kufner, Andreas ^a   Gbureck, Uwe ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCEMENTS; CEMENT PROPERTIES; CEMENT SURFACE; CEMENTITIOUS MATRICES; CYTOCOMPATIBILITY; GRINDING TIME; HUMAN OSTEOBLAST CELLS; HYDROGEN PHOSPHATES; IONIC SUBSTITUTIONS; MAGNESIUM AMMONIUM PHOSPHATES; POWDER MIXTURES; POWDER TO LIQUID RATIO; SETTING TIME; STRUVITES;

BONE CEMENT; CALCINATION; CALCIUM; CELL CULTURE; CEMENTS; GROWTH KINETICS; MAGNESIUM; MAGNESIUM POWDER; SETTING; STOICHIOMETRY;

AMMONIUM COMPOUNDS;

CALCIUM; CEMENT; MAGNESIUM DERIVATIVE; PHOSPHATE TRIMAGNESIUM; STRUVITE; UNCLASSIFIED DRUG;

ARTICLE; BIOCOMPATIBILITY; CELL GROWTH; CHEMICAL REACTION; COMPRESSION; CONTROLLED STUDY; HUMAN; HUMAN CELL; OSTEOBLAST; POWDER; PRIORITY JOURNAL; STOICHIOMETRY; SUBSTITUTION REACTION; SYNTHESIS;

BONE CEMENTS; BONE SUBSTITUTES; CALCIUM PHOSPHATES; CELL LINE; CELL PROLIFERATION; COMPRESSIVE STRENGTH; HUMANS; MAGNESIUM COMPOUNDS; MASS SPECTROMETRY; MATERIALS TESTING; MICROSCOPY, ELECTRON, SCANNING; MODELS, CHEMICAL; PHOSPHATES; POROSITY; POWDERS; TIME FACTORS; X-RAY DIFFRACTION;

EID: 79958166626     PISSN: 09574530     EISSN: 15734838     Source Type: Journal    
DOI: 10.1007/s10856-010-4220-4     Document Type: Article

References (28)

1. Frayssinet P, Rouquet N, Tourenne F, Fages J, Hardy D, Bonel G. Cell-degradation of calcium - phosphate ceramics. Cells Mater. 1993;3(4):383-94.
2. Gross KA, Berndt CC. Biomedical application of apatites. Rev Mineral Geochem. 2002;48:631-72.
3. Dorozhkin SV, Epple M. Biological and medical significance of calcium phosphates. Angew Chem Int Ed. 2002;41(17):3130-46. (Pubitemid 35021275)
4. Bohner M. Calcium orthophosphates in medicine: from ceramics to calcium phosphate cements. Injury. 2000;31:S37-47.
5. Breusch SJ, Kuhn KD. Bone cements based on polymethylmethacrylate. Orthopade. 2003;32(1):41-50. (Pubitemid 36596591)
6. Bohner M. Physical and chemical aspects of calcium phosphates used in spinal surgery. Eur Spine J. 2001;10:S114-21. (Pubitemid 33009314)
7. Pittet C, Lemaitre J. Mechanical characterization of brushite cements: a mohr circles' approach. J Biomed Mater Res. 2000; 53(6):769-80.
8. Theiss F, Apelt D, Brand BA, Kutter A, Zlinszky K, Bohner M, Matter S, Frei C, Auer JA, von Rechenberg B. Biocompatibility and resorption of a brushite calcium phosphate cement. Biomaterials. 2005;26(21):4383-94. (Pubitemid 40208599)
9. Oberle A, Theiss F, Bohner M, Muller J, Kastner SB, Frei C, Zlinszky K, Wunderlin S, Auer JA, von Rechenberg B. Investigation about the clinical use of brushite-and hydroxylapatitecement in sheep. Schweizer Archiv für Tierheilkunde. 2005; 147(11):482-90. (Pubitemid 41640918)
10. Kuemmerle JM, Oberle A, Oechslin C, Bohner M, Frei C, Boecken I, von Rechenberg B. Assessment of the suitability of a new brushite calcium phosphate cement for cranioplasty - an experimental study in sheep. J Craniomaxillofac Surg. 2005; 33(1):37-44. (Pubitemid 40197814)
11. Bohner M. pH variations of a solution after injecting brushite cements. Key Eng Mater. 2000;192-1:813-6.
12. Coe FL, Evan A, Worcester E. Kidney stone disease. J Clin Invest. 2005;115(10):2598-608. (Pubitemid 41434382)
13. Rahaman MS, Mavinic DS, Bhuiyan MIH, Koch FA. Exploring the determination of struvite solubility product from analytical results. Environ Tech. 2006;27(9):951-61. (Pubitemid 44669238)
14. Driessens FCM, Boltong MG, Wenz R, Meyer J. Calcium phosphates as fillers in struvite cements. Key Eng Mater. 2005;284-286: 161-4. (Pubitemid 46780333)
15. Hall DA, Stevens R, El Jazairi B. Effect of water content on the structure and mechanical properties of magnesia-phosphate cement mortar. J Am Ceram Soc. 1998;81(6):1550-6. (Pubitemid 128577136)
16. Sarkar AK. Hydration dehydration characteristics of struvite and dittmarite pertaining to magnesium ammonium phosphate cement systems. J Mater Sci. 1991;26(9):2514-8.
17. ASTM-Standard C266-99. Standard test method for time of setting of hydraulic cement paste by Gilmore needles. West Conshohocken: ASTM International; 2002.
18. Ewald A, Glückermann SK, Thull R, Gbureck U. Antimicrobial titanium/silver PVD coatings on titanium. BioMed Eng Online. 2006;5:22.
19. 4 Systems. Bull Chem Soc Jpn. 1958;31: 201-4.
20. Klammert U, Reuther T, Jahn C, Kübler AC, Gbureck U. Biocompatibility of brushite and monetite cell culture scaffolds made by 3D powder printing. Acta Biomaterialia. 2009;5:727-34.
21. Clarke SA, Hoskins NL, Jordan GR, Henderson SA, Marsh DR. In vitro testing of advanced JAX™ bone void filler system: species differences in the response of bone marrow stromal cells to β-tricalcium phosphate and carboxymethylcellulose gel. J Mater Sci Mater Med. 2007;18:2283-90. (Pubitemid 350165595)
22. Jalota S, Bhaduri SB, Tas AC. In vitro testing of calcium phosphate (HA, TCP, and biphasic HA-TCP) whiskers. J Biomed Mater Res. 2006;78A:481-90. (Pubitemid 44255497)
23. Driessens FCM, Boltong MG, Bermudez O, Planell JA, Ginebra MP, Fernandez E. Effective formulations for the preparation of calcium phosphate bone cements. J Mater Sci Mater Med. 1994;5:164-70. (Pubitemid 24122217)
24. Pina S, Olhero SM, Gheduzzi S, Miles AW, Ferreira JMF. Influence of setting liquid composition and liquid-to-powder ratio on properties of a Mg-substituted calcium phosphate cement. Acta Biomaterialia. 2009;5:1233-40.
25. Wu F, Su J, Wei J, Guo H, Liu CS. Injectable bioactive calcium-magnesium phosphate cement for bone regeneration. Biomed Mater. 2008;3:044105.
26. Gbureck U, Grolms O, Grover L, Barralet JE, Thull R. Mechanical activation of β-tricalcium phosphate and cement formation with Na2HPO4 solution. Biomaterials. 2003;24:4123-31. (Pubitemid 36809014)
27. Hofmann M, Mohammed AR, Perrie Y, Gbureck U, Barralet JE. High strength resorbable brushite bone cement with controlled drug releasing capabilities. Acta Biomaterialia. 2009;5:43-9.
28. Takahashi T, Yamamoto M, Ioku K, Goto S. Relationship between compressive strength and pore structure of hardened cement pastes. Adv Cem Res. 1997;9:25-30. (Pubitemid 127547444)