A 2-week, polysomnographic, safety study of sodium oxybate in obstructive sleep apnea syndrome

Sleep and Breathing

Volumn 15, Issue 1, 2011, Pages 13-20

  George, Charles F P ^a   Feldman, Neil ^b   Zheng, Yanping ^c,d   Steininger, Teresa L ^c   Grzeschik, Susanna M ^c,e   Lai, Chinglin ^c   Inhaber, Neil ^c,f  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b Clinical Research Group of St Petersburg   (United States)

^c JAZZ PHARMACEUTICALS   (United States)

^d Otsuka America Pharmaceutical Inc   (United States)

^e GENENTECH INC   (United States)

^f NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Gamma hydroxybutyrate GHB; Oxygen saturation; Polysomnography; Sleep apnea; Slow wave sleep; Xyrem sodium oxybate

Indexed keywords

MODAFINIL; OXYBATE SODIUM; PLACEBO; ZOLPIDEM;

ADULT; APNEA HYPOPNEA INDEX; ARTICLE; BEDTIME DOSAGE; CLINICAL ARTICLE; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG EFFECT; DRUG EFFICACY; DRUG FATALITY; DRUG INDUCED HEADACHE; DRUG SAFETY; EVENING DOSAGE; FEMALE; HUMAN; MALE; OXYGEN SATURATION; POLYSOMNOGRAPHY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SHORT COURSE THERAPY; SLEEP APNEA SYNDROME; SLEEP QUALITY; SLEEP TIME; SLOW WAVE SLEEP;

ADJUVANTS, ANESTHESIA; ADULT; BENZHYDRYL COMPOUNDS; CENTRAL NERVOUS SYSTEM STIMULANTS; COMBINED MODALITY THERAPY; CONTINUOUS POSITIVE AIRWAY PRESSURE; DISORDERS OF EXCESSIVE SOMNOLENCE; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; HYPNOTICS AND SEDATIVES; MALE; MIDDLE AGED; POLYSOMNOGRAPHY; PYRIDINES; SLEEP APNEA, OBSTRUCTIVE; SODIUM OXYBATE;

EID: 79958155429     PISSN: 15209512     EISSN: 15221709     Source Type: Journal    
DOI: 10.1007/s11325-009-0320-0     Document Type: Article

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