The significance of transient ischemic dilation in the setting of otherwise normal SPECT radionuclide myocardial perfusion images

Journal of Nuclear Cardiology

Volumn 18, Issue 2, 2011, Pages 220-229

  Valdiviezo, Carolina ^a,b   Motivala, Apurva A ^a,c   Hachamovitch, Rory ^d   Chamarthy, Murthy ^a,e   Navarro, Pablo C ^a,f   Ostfeld, Robert J ^a   Kim, Mimi ^g   Travin, Mark I ^a  

^a MONTEFIORE MEDICAL CENTER   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c NEW YORK PRESBYTERIAN HOSPITAL   (United States)

^d LERNER RESEARCH INSTITUTE   (United States)

^e BRIDGEPORT HOSPITAL   (United States)

^f BETH ISRAEL MEDICAL CENTER   (United States)

^g ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Coronary artery disease; Myocardial perfusion imaging; Transient ischemic dilation

Indexed keywords

ADULT; ANGIOCARDIOGRAPHY; ARTICLE; CARDIOVASCULAR PARAMETERS; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DISEASE SEVERITY; FEMALE; HUMAN; MALE; MORTALITY; MYOCARDIAL PERFUSION IMAGING; PRIORITY JOURNAL; PROGNOSIS; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SURVIVAL; TRANSIENT ISCHEMIC DILATION;

ADULT; AGED; CORONARY ANGIOGRAPHY; FEMALE; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL ISCHEMIA; MYOCARDIAL PERFUSION IMAGING; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 79958153291     PISSN: 10713581     EISSN: 15326551     Source Type: Journal    
DOI: 10.1007/s12350-011-9343-6     Document Type: Article

References (32)

1. Weiss AT, Berman DS, Lew AS, Nielsen J, Potkin B, Swan HJ, et al. Transient ischemic dilation of the left ventricle on stress thallium-201 scintigraphy: A marker of severe and extensive coronary artery disease. J Am Coll Cardiol 1987;9:752-9. (Pubitemid 17044919)
2. Iskandrian AS, Heo J, Nguyen T, Lyons E, Paugh E. Left ventricular dilatation and pulmonary thallium uptake after single-photon emission computer tomography using thallium-201 during adenosine- induced coronary hyperemia. Am J Cardiol 1990;66:807-11. (Pubitemid 20352259)
3. Heston TF, Sigg DM. Quantifying transient ischemic dilation using gated SPECT. J Nucl Med 2005;46:1990-6. (Pubitemid 46657444)
4. Hung GU, Lee KW, Chen CP, Lin WY, Yang KT. Relationship of transient ischemic dilation in dipyridamole myocardial perfusion imaging and stress-induced changes of functional parameters evaluated by Tl-201 gated SPECT. J Nucl Cardiol 2005;12:268-75.
5. Takeishi Y, Tono-oka I, Ikeda K, Komatani A, Tsuiki K, Yasui S. Dilatation of the left ventricular cavity on dipyridamole thallium- 201 imaging: A new marker of triple-vessel disease. Am Heart J 1991;121:466-73.
6. Mazzanti M, Germano G, Kiat H, Kavanagh PB, Alexanderson E, Friedman JD, et al. Identification of severe and extensive coronary artery disease by automatic measurement of transient ischemic dilation of the left ventricle in dual-isotope myocardial perfusion SPECT. J Am Coll Cardiol 1996;27:1612-20. (Pubitemid 26198012)
7. Abidov A, Bax JJ, Hayes SW, Cohen I, Nishina H, Yoda S, et al. Integration of automatically measured transient ischemic dilation ratio into interpretation of adenosine stress myocardial perfusion SPECT for detection of severe and extensive CAD. J Nucl Med 2004;45:1999-2007. (Pubitemid 47611627)
8. McClellan JR, Travin MI, Herman SD, Baron JI, Golub RJ, Gallagher JJ, et al. Prognostic importance of scintigraphic left ventricular cavity dilation during intravenous dipyridamole technetium- 99m sestamibi myocardial tomographic imaging in predicting coronary events. Am J Cardiol 1997;79:600-5. (Pubitemid 27143162)
9. Lette J, Bertrand C, Gossard D, Ruscito O, Cerino M, McNamara D, et al. Long-term risk stratification with dipyridamole imaging. Am Heart J 1995;129:880-6.
10. Veilleux M, Lette J, Mansur A, et al. Prognostic implications of transient left ventricular cavitary dilation during exercise and dipyridamole-thallium imaging. Can J Cardiol 1994;10:259-62.
11. Abidov A, Bax JJ, Hayes SW, Hachamovitch R, Cohen I, Gerlach J, Kang X, et al. Transient ischemic dilation ratio of the left ventricle is a significant predictor of future cardiac events in patients with otherwise normal myocardial perfusion SPECT. J Am Coll Cardiol 2003;42:1818-25. (Pubitemid 37433664)
12. Abidov A, Germano G, Berman DS. Transient ischemic dilation ratio: A universal high-risk diagnostic marker in myocardial perfusion imaging. J Nucl Cardiol 2007;14:497-500. (Pubitemid 47163571)
13. Berman DS, Hachamovitch R, Kiat H, Cohen I, Cabico JA, Wang FP, et al. Incremental value of prognostic testing in patients with known or suspected heart disease: A basis for optimal utilizationof exercise technetium-99 m sestamibi myocardial perfusion single- photon emission computed tomography. J Am Coll Cardiol 1995;26:639-47.
14. Germano G, Kiat H, Kavanagh PB, Moriel M, Mazzanti M, Su H, et al. Automatic quantification of ejection fraction from gated myocardial perfusion SPECT. J Nucl Med 1995;36:2138-47.
15. Henzlova MJ, CerqueiraMD,Hansen CL, TailleferR,Yao SS. Stress protocols and tracers. J Nucl Cardiol 2009. doi:10.1007/s12350- 009-9062-4 (http://www.asnc.org/imageuploads/ImagingGuidelinesStressProtocols021109.pdf, accessed 8/17/2010).
16. Holly TA, Abbott BG, Al-Mallah M, Calnon DA, Cohen MC, DiFilippo FP, Ficaro EP, Freeman MR, Hendel RC, Jain D, Leonard SM, Nichols KJ, Polk DM, Soman P. Single photon-emission computed tomography. J Nucl Cardiol 2010; published on line June 15, 2010. doi:10.1007/s12350-010-9246-y. (http://www.asnc.org/ imageuploads/ImagingGuidelineSPECTJune2010.pdf, accessed 8/17/10).
17. Berman DS, Shaw LJ, Hachamovitch R, Friedman JD, Polk DM, Hayes SW, et al. Comparative use of radionuclide stress testing, coronary artery calcium scanning, and noninvasive coronary angiography for diagnostic and prognostic cardiac assessment. Semin Nucl Med 2007;37:2-16. (Pubitemid 44854758)
18. Mark DB, Nelson CL, Califf RM, Harrell FE Jr, Lee KL, Jones RH, et al. Continuing evolution of therapy for coronary artery disease. Initial results from the era of coronary angioplasty. Circulation 1994;89:2015-25. (Pubitemid 24142776)
19. Yoon AJ, Melduni RM, Duncan SA, Ostfeld RJ, Travin MI. The effect of beta-blockers on the diagnostic accuracy of vasodilator pharmacologic SPECT myocardial perfusion imaging. J Nucl Cardiol 2009;16:358-67.
20. http://www.emerginghealthit.com/body.cfm?id=23. Last access date: August 17, 2010.
21. http://www.montefiore.org/guide/lookingglass/. Last access date: August 17, 2010.
22. Diamond GA, Forrester JS. Analysis of probability as an aid in the clinical diagnosis of coronary-artery disease. N Engl J Med. 1979;300:1350-8. (Pubitemid 9198112)
23. Baddi A, Bhatt M, Leonard SM, Hendel RC. Significance of transient ischemic left ventricular dilation in the absence of SPECT perfusion defects. Circulation 2002;106:II-618 (abstract).
24. Hakeem A, Bhatti S, Cook JR, Chang SM. Isolated transient ischemic dilation and the risk of adverse cardiac events in a cohort of high risk individuals undergoing myocardial perfusion SPECT imaging. J Am Coll Cardiol 2010; 55:A90.E854 (abstract).
25. Stolzenberg J. Dilatation of left ventricular cavity on stress thallium scan as an indicator of ischemic disease. Clin Nucl Med 1980;5:289-91. (Pubitemid 10042186)
26. McLaughlin MG, Danias PG. Transient ischemic dilation: A powerful diagnostic and prognostic finding of stress myocardial perfusion imaging. J Nucl Cardiol 2002;9:663-7. (Pubitemid 36050213)
27. Sugihara H, Shiga K, Umamoto I, Harada Y, Katahira T, Nakagawa T, et al. Assessment of transient dilation of the left ventricular cavity in patients with hypertrophic cardiomyopathy by exercise thallium-0201 scintigraphy [in Japanese]. Kaku Igaku 1990;27:1281-9.
28. Robinson VJ, Corley JH, Marks DS, Eberhardt LW, Eubig C, Burke GJ, et al. Causes of transient dilatation of the left ventricle during myocardial perfusion imaging. Am J Roentgenol 2000;174:1349-52. (Pubitemid 30261791)
29. Smelley MP, Virnich DE, Williams KA, Ward RP. A hypertensive response to exercise is associated with transient ischemic dilation on myocardial perfusion SPECTimaging. JNuclCardiol 2007;14:537-43. (Pubitemid 47163553)
30. Lin DA, Harb TS, Yoder SR, Mackin ML, Schwartz RG. Transient ischemic dilation without angiographically detectable coronaryartery disease is associated with left ventricular hypertrophy and low mortality. J Nucl Cardiol 2003;10:S46 (abstract).
31. Emmett L, Magee M, Freedman SB, Van der Wall H, Bush V, Trieu J, et al. The role of left ventricular hypertrophy and diabetes in the presence of transient ischemic dilation of the left ventricle on myocardial perfusion SPECT images. J Nucl Med 2005;46:1596-601. (Pubitemid 46211582)
32. Hansen CL, Sangrigoli R, Nkadi E, Kramer M. Comparison of pulmonary uptake with transient cavity dilation after exercise thallium-201 perfusion imaging. J Am Coll Cardiol 1999;33:1323-7.