Rejection of intradermally injected syngeneic tumor cells from mice by specific elimination of tumor-associated macrophages with liposome-encapsulated dichloromethylene diphosphonate, followed by induction of CD11b +/CCR3 -/Gr-1 - cells cytotoxic against the tumor cells

Cancer Immunology, Immunotherapy

Volumn 58, Issue 12, 2009, Pages 2011-2023

  Takahashi, Takeshi ^a   Ibata, Minenori ^a   Yu, Zhiqian ^b   Shikama, Yosuke ^b   Endo, Yasuo ^b   Miyauchi, Yasunori ^c   Nakamura, Masanori ^c   Tashiro Yamaji, Junko ^a   Miura Takeda, Sayako ^a   Shimizu, Tetsunosuke ^a   Okada, Masashi ^a   Ueda, Koichi ^a   Kubota, Takahiro ^a   Yoshida, Ryotaro ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

^c SHOWA UNIVERSITY SCHOOL OF DENTISTRY   (Japan)

Author keywords

DMDP liposome; Macrophage; Rodent; Tumor rejection

Indexed keywords

CCR3 PROTEIN, MOUSE; CD11B ANTIGEN; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR3; CLODRONIC ACID; GR 1 PROTEIN, MOUSE; GR-1 PROTEIN, MOUSE; LIPOSOME;

ANIMAL; ARTICLE; BIOSYNTHESIS; C57BL MOUSE; CANCER TRANSPLANTATION; CYTOTOXICITY; DBA MOUSE; DRUG EFFECT; EXPERIMENTAL MELANOMA; EXPERIMENTAL NEOPLASM; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; INTRADERMAL DRUG ADMINISTRATION; LEWIS CARCINOMA; MACROPHAGE; MOUSE; SQUAMOUS CELL CARCINOMA; TUMOR CELL LINE;

ANIMALS; ANTIGENS, CD11B; CARCINOMA, LEWIS LUNG; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CLODRONIC ACID; CYTOTOXICITY, IMMUNOLOGIC; IMMUNOHISTOCHEMISTRY; INJECTIONS, INTRADERMAL; LIPOSOMES; MACROPHAGES; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; RECEPTORS, CCR3; RECEPTORS, CHEMOKINE;

EID: 79958134264     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-009-0708-5     Document Type: Article

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