A revised model for end-stage liver disease optimizes prediction of mortality among patients awaiting liver transplantation

Gastroenterology

Volumn 140, Issue 7, 2011, Pages 1952-1960

  Leise, Michael D ^a   Kim, W Ray ^a,b   Kremers, Walter K ^b   Larson, Joseph J ^b   Benson, Joanne T ^b   Therneau, Terry M ^b  

^a MAYO CLINIC   (United States)

^b Mayo Clinic   (United States)

Author keywords

Liver Disease; Prognosis; Surgery; Survival

Indexed keywords

BILIRUBIN; CREATININE; SODIUM;

ADULT; ARTICLE; END STAGE LIVER DISEASE; FEMALE; HUMAN; INTERNATIONAL NORMALIZED RATIO; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MEDICAL EDUCATION; MORTALITY; OUTCOME ASSESSMENT; PREDICTION; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; SCORING SYSTEM;

EID: 79958131982     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2011.02.017     Document Type: Article

References (24)

1. M. Malinchoc, P.S. Kamath, F.D. Gordon, C.J. Peine, J. Rank, and P.C. ter Borg A model to predict poor survival in patients undergoing transjugular intrahepatic portosystemic shunts Hepatology 31 2000 864 871 (Pubitemid 30169932)
2. P.S. Kamath, R.H. Wiesner, and M. Malinchoc A model to predict survival in patients with end-stage liver disease Hepatology 33 2001 464 470 (Pubitemid 32119037)
3. R.B. Freeman, R.H. Wiesner, E. Edwards, A. Harper, R. Merion, and R. Wolfe Results of the first year of the new liver allocation plan Liver Transpl 10 2004 7 15 (Pubitemid 38885887)
4. M.A. Fink, P.W. Angus, and P.J. Gow Liver transplant recipient selection: MELD vs. clinical judgment Liver Transpl 11 2005 621 626 (Pubitemid 40872899)
5. R. Wiesner, E. Edwards, and R. Freeman Model for end-stage liver disease (MELD) and allocation of donor livers Gastroenterology 124 2003 91 96 (Pubitemid 36055342)
6. W.R. Kim, S.W. Biggins, and W.K. Kremers Hyponatremia and mortality among patients on the liver-transplant waiting list N Engl J Med 359 2008 1018 1026
7. P. Sharma, D.E. Schaubel, C.S. Sima, R.M. Merion, and A.S. Lok Re-weighting the model for end-stage liver disease score components Gastroenterology 135 2008 1575 1581
8. Hastie T, Tibshirani R. Generalized additive models. 1990;43.
9. R.B. D'Agostino Sr, S. Grundy, L.M. Sullivan, and P. Wilson Validation of the Framingham coronary heart disease prediction scores: results of a multiple ethnic groups investigation JAMA 286 2001 180 187 (Pubitemid 32640849)
10. F.E. Harrell Jr, K.L. Lee, and D.B. Mark Multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors Stat Med 15 1996 361 387 (Pubitemid 26072233)
11. W. Kremers Concordance for survival time data: fixed and time-dependent covariates and possible ties in predictor and time Technical report series no. 80 2007 Department of Health Science Research, Mayo Clinic Rochester, MN
12. P.S. Kamath, and W.R. Kim The model for end-stage liver disease (MELD) Hepatology 45 2007 797 805 (Pubitemid 46450631)
13. A. Robert, and O. Chazouilleres Prothrombin time in liver failure: time, ratio, activity percentage, or international normalized ratio? Hepatology 24 1996 1392 1394 (Pubitemid 26399036)
14. M.J. Kovacs, A. Wong, and K. MacKinnon Assessment of the validity of the INR system for patients with liver impairment Thromb Haemost 71 1994 727 730 (Pubitemid 24177960)
15. International Committee for Standardization in Haematology, International Committee on Thrombosis and Haemostasis ICSH/ICTH recommendations for reporting prothrombin time in oral anticoagulant control Thromb Haemost 53 1985 155 156
16. A. Gines, A. Escorsell, and P. Gines Incidence, predictive factors, and prognosis of the hepatorenal syndrome in cirrhosis with ascites Gastroenterology 105 1993 229 236 (Pubitemid 23234041)
17. G. Fernandez-Esparrach, A. Sanchez-Fueyo, and P. Gines A prognostic model for predicting survival in cirrhosis with ascites J Hepatol 34 2001 46 52 (Pubitemid 32102551)
18. J. Llach, P. Gines, and V. Arroyo Prognostic value of arterial pressure, endogenous vasoactive systems, and renal function in cirrhotic patients admitted to the hospital for the treatment of ascites Gastroenterology 94 1988 482 487 (Pubitemid 18054789)
19. L. Shear, J. Kleinerman, and G.J. Gabuzda Renal failure in patients with cirrhosis of the liver I. Clinical and pathologic characteristics Am J Med 39 1965 184 198
20. L.E. Earley, and C.A. Sanders The effect of changing serum osmolality on the release of antidiuretic hormone in certain patients with decompensated cirrhosis of the liver and low serum osmolality J Clin Invest 38 1959 545 550
21. V. Arroyo, J. Rodes, M.A. Gutierrez-Lizarraga, and L. Revert Prognostic value of spontaneous hyponatremia in cirrhosis with ascites Am J Dig Dis 21 1976 249 256
22. S.W. Biggins, W.R. Kim, and N.A. Terrault Evidence-based incorporation of serum sodium concentration into MELD Gastroenterology 130 2006 1652 1660 (Pubitemid 43668830)
23. A.E. Ruf, W.K. Kremers, and L.L. Chavez Addition of serum sodium into the MELD score predicts waiting list mortality better than MELD alone Liver Transpl 11 2005 336 343 (Pubitemid 40458408)
24. D.M. Heuman, S.G. Abou-Assi, and A. Habib Persistent ascites and low serum sodium identify patients with cirrhosis and low MELD scores who are at high risk for early death Hepatology 40 2004 802 810 (Pubitemid 39288112)