Blockage of the channel to heme by the E87 side chain in the GAF domain of Mycobacterium tuberculosis DosS confers the unique sensitivity of DosS to oxygen

FEBS Letters

Volumn 585, Issue 12, 2011, Pages 1873-1878

  Cho, Ha Yeon ^a   Cho, Hyo Je ^a   Kim, Myung Hee ^b   Kang, Beom Sik ^a,c  

^a Kyungpook National University   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^c NONE   (South Korea)

Author keywords

DosS; GAF domain; Heme protein; Mycobacterium tuberculosis; Oxygen sensor; Redox sensor

Indexed keywords

HEME; OXYGEN; PROTEIN DOSS; PROTEIN DOST; PROTEIN HISTIDINE KINASE; PROTEIN S GAF; PROTEIN T GAF; UNCLASSIFIED DRUG;

ABSORPTION SPECTROSCOPY; AERATION; ALPHA HELIX; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STRUCTURE;

ANOXIA; HEME; MYCOBACTERIUM TUBERCULOSIS; OXIDATION-REDUCTION; OXYGEN; PHOSPHORIC DIESTER HYDROLASES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY;

MYCOBACTERIUM TUBERCULOSIS;

EID: 79958131422     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2011.04.050     Document Type: Article

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