Effects of domperidone on gastric emptying: A crossover study using a continuous real-time 13C breath test (breathid system)

Hepato-Gastroenterology

Volumn 58, Issue 106, 2011, Pages 637-641

  Sakamoto, Yasunari ^a   Kato, Shingo ^a   Sekino, Yusuke ^a   Sakai, Eiji ^a   Uchiyama, Takashi ^a   Iida, Hiroshi ^a   Hosono, Kunihiro ^a   Endo, Hiroki ^a   Fujita, Koji ^a   Koide, Tomoko ^a   Takahashi, Hirokazu ^a   Yoneda, Masato ^a   Tokoro, Chikako ^a   Goto, Ayumu ^a   Abe, Yasunobu ^a   Kobayashi, Noritoshi ^a   Kubota, Kensuke ^a   Maeda, Shin ^a   Nakajima, Atsushi ^a   Inamori, Masahiko ^a  

^a YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

Domperidone; Dopamine D2 receptor antagonist; Gastric emptying; Nausea

Indexed keywords

DOMPERIDONE;

13C ACETIC ACID BREATH TEST; ADULT; ARTICLE; BREATH ANALYSIS; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIET RESTRICTION; DOPAMINE RECEPTOR BLOCKING; DRUG EFFECT; FLUID INTAKE; HUMAN; HUMAN EXPERIMENT; ISOTOPE LABELING; MALE; NON INVASIVE PROCEDURE; NORMAL HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; STOMACH EMPTYING; STOMACH SCINTISCANNING; TEST MEAL;

ADULT; BREATH TESTS; CARBON ISOTOPES; CROSS-OVER STUDIES; DOMPERIDONE; DOPAMINE ANTAGONISTS; GASTRIC EMPTYING; HUMANS; MALE; RECEPTORS, DOPAMINE D2;

EID: 79958129111     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Ahmad N, Keith-Ferris J, Gooden E, Abell T: Making a case for domperidone in the treatment of gastrointestinal motility disorders. Curr Opin Pharmacol 2006; 6:571-576. (Pubitemid 44660947)
2. Barone JA: Domperidone: a peripherally acting dopamine2-receptor antagonist. Ann Pharmacother 1999; 33:429-440.
3. 18C continuous breath test (BreathID System). Digestion 2006; 20:74-238.
4. 13C breath test (BreathID system). J Gastroenterol 2007; 42:539-42.
5. 13C breath test (BreathID system). Dig Dis Sci 2009; 54:816-8.
6. 13C breath test (BreathID system). Hepato-gastroenterology 2008; 55:1905-1907.
7. 13C breath test (BreathID system). Hepato-gastroenterology 2009; 56:918-20.
8. 13C-octanoate breath test for patients with nonalcoholic steatohepatitis using the BreathlD system. Hepato-gastroenterology 2009; 56:1436-8.
9. Shimoyama Y, Kusano M, Kawamura O, Zai H, Kuribayashi S, Higuchi T, Nagoshi A, Maeda M, Mori M: High-viscosity liquid meal accelerates gastric emptying. Neurogastroenterol Motil 2007; 19:879-86. (Pubitemid 350060609)
10. Zai H, Kusano M, Hosaka H, Shimoyama Y, Nagoshi A, Maeda M, Kawamura O, Mori M: Monosodium L-glutamate added to a high-energy, high-protein liquid diet promotes gastric emptying. Am J Clin Nutr 2009; 89:431-5.
11. Zai H, Kusano M: Investigation of gastric emptying disorders in patients with functional dyspepsia reveals impaired inhibitory gastric emptying regulation in the early postcibal period. Digestion 2009; 79Suppl1:13-8.
12. 13C] acetate breath test. Dig Dis Sci 1994; 39:107S-109S.
13. Sanaka M, Anjiki H, Yamamoto T, Kuyama Y. Rabeprazole delays gastric emptying of a nutrient liquid. J Gastroenterol Hepatol 2007; 22:1806-1809. (Pubitemid 47525080)
14. Sanaka M, Yamamoto T, Anjiki H, Nagasawa K, Kuyama Y: Effects of agar and pectin on gastric emptying and postprandial glycaemic profiles in healthy human volunteers. Clin Exp Pharmacol Physiol 2007; 34:1151-1155.
15. Ghoos YF, Maes BD, Geypens BJ, Mys G, Hiele MI, Rutgeerts PJ, Vantrappen G: Measurement of gastric emptying rate of solids by means of a carbon-labeled octanoic acid breath test. Gastroenterology 1993; 104:1640-7. (Pubitemid 23235453)
16. 13C-octanoate breath test. Digestion 2005; 72:189-94. (Pubitemid 41507279)
17. 13C-octanoic acid breath test. J Gastroenterol 2005; 40:578-32.
18. Reddymasu SC, Soykan I, McCallum R: Domperidone: review of pharmacology and clinical applications in gastroenterology. Am J Gastroenterol 2007; 102:2036-2045. (Pubitemid 47301500)
19. Koch KL, Stern RM, Stewart WR, Vasey MW: Gastric emptying and gastric myoelectrical activity in patients with diabetic gastroparesis: effect of long-term domperidone treatment. Am J Gastroenterol 1989; 84:1069-75. (Pubitemid 19237995)
20. Horowitz M, O'Donovan D, Jones KL, Feinle C, Rayner CK, Samsom M: Gastric emptying in diabetes: clinical significance and treatment. Diabet Med 2002; 19:177-94. (Pubitemid 34429648)
21. Heer M, Müller-Duysing W, Benes I, Weitzel M, Pirovino M, Altorfer J, Schmid M: Diabetic gastroparesis: treatment with domperidone - a double-blind, placebo-controlled trial. Digestion 1983; 27:214-7. (Pubitemid 14226074)
22. Baeyens R, Reyntjens A, Van de Velde E: Effects of domperidone (R 33812) on the motor function of the stomach and small intestine. A double-blind evaluation. Arzneimittelforschung 1978; 28:682-6.
23. Weihrauch TR, Ehl W: Effect of domperidone on the motility of antrum, pylorus and duodenum in man. Scand J Gastroenterol Suppl 1981; 67:195-8. (Pubitemid 11123090)