Formation of lamellar cross bridges in the annulus fibrosus of the intervertebral disc is a consequence of vascular regression

Matrix Biology

Volumn 30, Issue 4, 2011, Pages 267-274

  Smith, Lachlan J ^a   Elliott, Dawn M ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Annulus fibrosus; Blood vessel; Cross bridge; Development; Intervertebral disc

Indexed keywords

CD31 ANTIGEN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANNULUS FIBROSUS; ANTERIOR POSTERIOR AXIS; ARTICLE; BLOOD VESSEL; CADAVER; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; ENDOTHELIUM CELL; FETUS; FETUS DEVELOPMENT; GESTATIONAL AGE; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; IMMUNOHISTOCHEMISTRY; INTERVERTEBRAL DISK; LAMELLAR BODY; LUMBAR SPINE; NONHUMAN; PHASE CONTRAST MICROSCOPY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SHEEP; SPINE; VASCULARIZATION;

ADULT; AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; ANTIGENS, CD31; CARDIOVASCULAR PHYSIOLOGICAL PROCESSES; HUMANS; INTERVERTEBRAL DISC; LUMBOSACRAL REGION; MIDDLE AGED; SHEEP;

OVIS ARIES;

EID: 79958122838     PISSN: 0945053X     EISSN: 15691802     Source Type: Journal    
DOI: 10.1016/j.matbio.2011.03.009     Document Type: Article

References (35)

1. Adams M.A., McNally D.S., Dolan P. 'Stress' distributions inside intervertebral discs, the effects of age and degeneration. J. Bone Joint Surg. Br. 1996, 78:965-972.
2. Ali R., Le Maitre C.L., Richardson S.M., Hoyland J.A., Freemont A.J. Connective tissue growth factor expression in human intervertebral disc: implications for angiogenesis in intervertebral disc degeneration. Biotech. Histochem. 2008, 83:239-245.
3. Beckstein J.C., Sen S., Schaer T.P., Vresilovic E.J., Elliott D.M. Comparison of animal discs used in disc research to human lumbar disc: axial compression mechanics and glycosaminoglycan content. Spine 2008, 33:E166-E173.
4. Costi J.J., Stokes I.A., Gardner-Morse M., Laible J.P., Scoffone H.M., Iatridis J.C. Direct measurement of intervertebral disc maximum shear strain in six degrees of freedom: motions that place disc tissue at risk of injury. J. Biomech. 2007, 40:2457-2466.
5. Dahia C.L., Mahoney E.J., Durrani A.A., Wylie C., Dahia C.L., Mahoney E.J., Durrani A.A., Wylie C. Postnatal growth, differentiation, and aging of the mouse intervertebral disc. Spine 2009, 34:447-455.
6. Elliott D.M., Yerramalli C.S., Beckstein J.C., Boxberger J.I., Johannessen W., Vresilovic E.J. The effect of relative needle diameter in puncture and sham injection animal models of degeneration. Spine 2008, 33:588-596.
7. Fazzalari N.L., Costi J.J., Hearn T.C., Fraser R.D., Vernon-Roberts B., Hutchinson J., Manthey B.A., Parkinson I.H., Sinclair C. Mechanical and pathologic consequences of induced concentric anular tears in an ovine model. Spine 2001, 26:2575-2581.
8. Hampton D., Laros G., McCarron R., Franks D. Healing potential of the anulus fibrosus. Spine 1989, 14:398-401.
9. Hayes A.J., Benjamin M., Ralphs J.R. Role of actin stress fibres in the development of the intervertebral disc: cytoskeletal control of extracellular matrix assembly. Dev. Dyn. 1999, 215:179-189.
10. Iatridis J.C., MaClean J.J., Ryan D.A. Mechanical damage to the intervertebral disc annulus fibrosus subjected to tensile loading. J. Biomech. 2005, 38:557-565.
11. Marchand F., Ahmed A.M. Investigation of the laminate structure of lumbar disc anulus fibrosus. Spine 1990, 15:402-410.
12. Maroudas A., Stockwell R.A., Nachemson A., Urban J. Factors involved in the nutrition of the human lumbar intervertebral disc: cellularity and diffusion of glucose in vitro. J. Anat. 1975, 120:113-130.
13. Melrose J., Smith S.M., Appleyard R.C., Little C.B. Aggrecan, versican and type VI collagen are components of annular translamellar crossbridges in the intervertebral disc. Eur. Spine J. 2008, 17:314-324.
14. Nerlich A.G., Schaaf R., Walchli B., Boos N. Temporo-spatial distribution of blood vessels in human lumbar intervertebral discs. Eur. Spine J. 2007, 16:547-555.
15. O'Connell G.D., Vresilovic E.J., Elliott D.M. Comparison of animals used in disc research to human lumbar disc geometry. Spine 2007, 32:328-333.
16. O'Connell G.D., Vresilovic E.J., Elliott D.M. Human intervertebral disc internal strain in compression: the effect of disc region, loading position, and degeneration. J. Orthop. Res. 2011, 29:547-555.
17. Osti O.L., Vernon-Roberts B., Fraser R.D. Volvo Award in experimental studies, anulus tears and intervertebral disc degeneration. An experimental study using an animal model. Spine 1990, 15:762-767.
18. Pezowicz C.A., Robertson P.A., Broom N.D. The structural basis of interlamellar cohesion in the intervertebral disc wall. J. Anat. 2006, 208:317-330.
19. Pufe T., Petersen W., Kurz B., Tsokos M., Tillmann B., Mentlein R. Mechanical factors influence the expression of endostatin-an inhibitor of angiogenesis-in tendons. J. Orthop. Res. 2003, 21:610-616.
20. Rudert M., Tillmann B. Detection of lymph and blood vessels in the human intervertebral disc by histochemical and immunohistochemical methods. Ann. Anat. 1993, 175:237-242.
21. Rufai A., Benjamin M., Ralphs J.R. The development of fibrocartilage in the rat intervertebral disc. Anat Embryol Berl 1995, 192:53-62.
22. Schollum M.L., Robertson P.A., Broom N.D. ISSLS prize winner: microstructure and mechanical disruption of the lumbar disc annulus: part I: a microscopic investigation of the translamellar bridging network. Spine 2008, 33:2702-2710.
23. Schollum M.L., Robertson P.A., Broom N.D. A microstructural investigation of intervertebral disc lamellar connectivity: detailed analysis of the translamellar bridges. J. Anat. 2009, 214:805-816.
24. Schollum M.L., Appleyard R.C., Little C.B., Melrose J. A detailed microscopic examination of alterations in normal anular structure induced by mechanical destabilization in an ovine model of disc degeneration. Spine 2010, 35:1965-1973.
25. Smith L.J., Nerurkar N.L., Choi K.S., Harfe B.D., Elliott D.M. Degeneration and regeneration of the intervertebral disc: lessons from development. Dis. Model. Mech. 2011, 4:31-41.
26. Sobajima S., Kompel J.F., Kim J.S., Wallach C.J., Robertson D.D., Vogt M.T., Kang J.D., Gilbertson L.G. A slowly progressive and reproducible animal model of intervertebral disc degeneration characterized by MRI, X-ray, and histology. Spine 2005, 30:15-24.
27. Thompson J.P., Pearce R.H., Schechter M.T., Adams M.E., Tsang I.K., Bishop P.B. Preliminary evaluation of a scheme for grading the gross morphology of the human intervertebral disc. Spine 1990, 15:411-415.
28. Thompson R.E., Pearcy M.J., Downing K.J., Manthey B.A., Parkinson I.H., Fazzalari N.L. Disc lesions and the mechanics of the intervertebral joint complex. Spine 2000, 25:3026-3035.
29. Tsantrizos A., Ito K., Aebi M., Steffen T. Internal strains in healthy and degenerated lumbar intervertebral discs. Spine 2005, 30:2129-2137.
30. Urban J.P., Smith S., Fairbank J.C. Nutrition of the intervertebral disc. Spine 2004, 29:2700-2709.
31. Vernon-Roberts B. Disc pathology and disease states. The Biology of the Intervertebral Disc 1988, 73-119. CRC Press. P. Ghosh (Ed.).
32. Videman T., Nurminen M. The occurrence of anular tears and their relation to lifetime back pain history: a cadaveric study using barium sulfate discography. Spine 2004, 29:2668-2676.
33. Wilke H.J., Kettler A., Claes L.E. Are sheep spines a valid biomechanical model for human spines?. Spine 1997, 22:2365-2374.
34. Yu J., Winlove P.C., Roberts S., Urban J.P. Elastic fibre organization in the intervertebral discs of the bovine tail. J. Anat. 2002, 201:465-475.
35. Yu J., Tirlapur U., Fairbank J., Handford P., Roberts S., Winlove C.P., Cui Z., Urban J. Microfibrils, elastin fibres and collagen fibres in the human intervertebral disc and bovine tail disc. J. Anat. 2007, 210:460-471.