Highly potent activity of (1R,2R,6S)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3- ene-1,2-diol in animal models of parkinson's disease

Journal of Medicinal Chemistry

Volumn 54, Issue 11, 2011, Pages 3866-3874

  Ardashov, Oleg V ^a   Pavlova, Alla V ^a   Il'ina, Irina V ^a   Morozova, Ekaterina A ^a   Korchagina, Dina V ^a   Karpova, Elena V ^a   Volcho, Konstantin P ^a   Tolstikova, Tat'yana G ^a   Salakhutdinov, Nariman F ^a  

^a N N VOROZHTSOV NOVOSIBIRSK INSTITUTE OF ORGANIC CHEMISTRY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; 3 METHYL 6 (PROP 1 EN 2 YL)CYCLOHEX 3 ENE 1,2 DIOL; ANTIPARKINSON AGENT; HALOPERIDOL; LEVODOPA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFICACY; DRUG STRUCTURE; DRUG SYNTHESIS; EXPLORATORY BEHAVIOR; FEMALE; LOCOMOTION; MALE; MOUSE; NONHUMAN; PARKINSON DISEASE; RAT; STEREOISOMERISM;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ANIMALS; ANTIPARKINSON AGENTS; CYCLOHEXANOLS; DISEASE MODELS, ANIMAL; DOPAMINE ANTAGONISTS; DRUG SYNERGISM; HALOPERIDOL; LEVODOPA; MICE; MICE, INBRED C57BL; MOLECULAR CONFORMATION; MOTOR ACTIVITY; NEUROTOXINS; PARKINSON DISEASE; PARKINSONIAN DISORDERS; RATS; RATS, WISTAR; RECEPTORS, NEUROTRANSMITTER; STEREOISOMERISM;

EID: 79958110435     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm2001579     Document Type: Article

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