Cellular reprogramming: Opportunities and challenges

American Laboratory

Volumn 43, Issue 6, 2011, Pages 40-43

  Chu, Vi ^a   Noble, Amy ^a   Rollins, Louise ^a  

^a Stem Cells/Cell Biology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL TYPES; DISEASE RESEARCH; PLURIPOTENT; PLURIPOTENT STEM CELLS; SOMATIC CELLS;

STEM CELLS; TRANSCRIPTION FACTORS;

RESEARCH;

EID: 79958083698     PISSN: 00447749     EISSN: None     Source Type: Trade Journal    
DOI: None     Document Type: Article

References (6)

1. Takahashi, K.; Tanabe, K. et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factor. Cell 2007, 131, 861-72. (Pubitemid 350138099)
2. Baker, M. Integration-free iPS cells. Nature Reports Stem Cells; Oct. 16, 2008.
3. Sommer, C. A.; Gianotti Sommer, A. et al. Excision of reprogramming transgenes improves differentiation potential of iPS cells generated with a single excisable vector. Stem Cells 2010, 28 (1), 64-74.
4. Jaenisch, R.; Young, R. Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming. Cell 2008, 132 (4), 567-82. (Pubitemid 351253686)
5. Warren, L.; Manos, P. D. et al. Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 2010. In press.
6. Guidance for Industry: Drug-Induced Liver Injury; U. S. Department of Health and Human Services, July 2009.