Structural heterogeneity and ligand gating in ferric methanosarcina acetivorans protoglobin mutants

IUBMB Life

Volumn 63, Issue 5, 2011, Pages 287-294

  Pesce, Alessandra ^a   Tilleman, Lesley ^b   Dewilde, Sylvia ^b   Ascenzi, Paolo ^c   Coletta, Massimo ^d,e   Ciaccio, Chiara ^d,e   Bruno, Stefano ^f   Moens, Luc ^b   Bolognesi, Martino ^g   Nardini, Marco ^g  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF ANTWERP   (Belgium)

^c ROMA TRE UNIVERSITY   (Italy)

^d UNIVERSITY OF ROME TOR VERGATA   (Italy)

^e Interuniversity Consortium for the Research on the Chemistry of Metals in Biological Systems   (Italy)

^f UNIVERSITY OF PARMA   (Italy)

^g UNIVERSITY OF MILAN   (Italy)

Author keywords

archaea heme protein; crystal structure; GCS, globin coupled sensor; heme reactivity; MaPgb, protoglobin from Methanosarcina acetivorans C2A; MaPgbO2, oxygenated ferrous MaPgb; Methanosarcina acetivorans protoglobin; Pgb, protoglobin; protein matrix tunnels; rms, root mean squared

Indexed keywords

GLOBIN; HEME; IRON; METHANOSARCINA ACETIVORANS PROTOGLOBIN; PHENYLALANINE; TRYPTOPHAN; TYROSINE; UNCLASSIFIED DRUG;

LIGAND BINDING; METHANOSARCINA ACETIVORANS; NONHUMAN; OXYGENATION; PROTEIN CARBONYLATION; PROTEIN POLYMORPHISM; PROTEIN STRUCTURE; REVIEW;

ARCHAEAL PROTEINS; GLOBINS; HEME; IRON; LIGANDS; METHANOSARCINA; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN FOLDING;

METHANOSARCINA ACETIVORANS;

EID: 79958066497     PISSN: 15216543     EISSN: 15216551     Source Type: Journal    
DOI: 10.1002/iub.484     Document Type: Review

References (13)

1. Hou, S., Freitas, T. A. K., Larsen, R. W., Piatibratov, M., Sivozhelezov, V., Yamamoto, A., Meleshkevitch, E. A., Zimmer, M., Ordal, G. W., and, Alam, M., (2001) Globin-coupled sensors: a class of heme- containing sensors in Archaea and Bacteria. Proc. Natl. Acad. Sci. USA 98, 9353-9358. (Pubitemid 32743920)
2. Freitas, T. A. K., Hou, S., Dioum, E. M., Saito, J., Newhouse, J., Gonzalez, G., Gilles-Gonzalez, M.-A., and, Alam, M., (2004) Ancestral hemoglobins in Archaea. Proc. Natl. Acad. Sci. USA 101, 6675-6680. (Pubitemid 38586033)
3. Freitas, T. A. K., Saito, J., Hou, S., and, Alam, M., (2005) Globin-coupled sensors, protoglobins, and the last universal common ancestor. J. Inorg. Biochem. 99, 23-33. (Pubitemid 39642969)
4. Vinogradov, S. N., Hoogewijs, D., Bailly, X., Arredondo-Peter, R., Gough, J., Dewilde, S., Moens, L., and, Vanfleteren, J., (2006) A phylogenomic profile of globins. BMC Evol. Biol. 6, 31.
5. Vinogradov, S. N., Hoogewijs, D., Bailly, X., Mizuguchi, K., Dewilde, S., Moens, L., and, Vanfleteren, J., (2007) A model of globin evolution. Gene 398, 132-142. (Pubitemid 47068897)
6. Nardini, M., Pesce, A., Thijs, L., Saito, J. A., Dewilde, S., Alam, M., Ascenzi, P., Coletta, M., Ciaccio, C., Moens, L., and, Bolognesi, M., (2008) Archaeal protoglobin structure indicates new ligand diffusionpaths and modulation of haem-reactivity. EMBO Rep. 9, 157-163. (Pubitemid 351223453)
7. Zhang, W., and, Phillips, G. N. Jr., (2003) Structure of the oxygen sensor in Bacillus subtilis: signal transduction of chemotaxis by control of symmetry. Structure 11, 1097-1110. (Pubitemid 37103071)
8. Pesce, A., Thijs, L., Nardini, M., Desmet, F., Sisinni, L., Gourlay, L., Bolli, A., Coletta, M., Van Doorslaer, S., Wan, X., Alam, M., Ascenzi, P., Moens, L., Bolognesi, M., and, Dewilde, S., (2009) HisE11 and HisF8 provide bis-histidyl heme hexa-coordination in the globin domain of Geobacter sulfurreducens globin-coupled sensor. J. Mol. Biol. 386, 246-260.
9. Bonamore, A., Farina, A., Gattoni, M., Schinina, M., Bellelli, M. E., and, Boffi, A., (2003) Interaction with membrane lipids and heme ligand binding properties of Escherichia coli flavohemoglobin. Biochemistry 42, 5792-5801. (Pubitemid 36582871)
10. Rinaldi, A. C., Bonamore, A., Macone, A., Boffi, A., Bozzi, A., and, Di Giulio, A., (2006) Interaction of Vitreoscilla hemoglobin with membrane lipids. Biochemistry 45, 4069-4076.
11. Appleby, C. A., Wittenberg, B. A., and, Wittenberg, J. B., (1973) Nicotinic acid as a ligand affecting leghemoglobin structure and oxygen reactivity. Proc. Natl. Acad. Sci. USA 70, 564-568.
12. Bikiel, D. E., Forti, F., Boechi, L., Nardini, M., Luque, F. J., Martì, M. A., and, Estrin, D. A., (2010) Role of heme distortion on oxygen affinity in heme proteins: the protoglobin case. J. Phys. Chem. B 114, 8536-8543.
13. Milani, M., Pesce, A., Bolognesi, M., Bocedi, A., and, Ascenzi, P., (2003) Substrate channeling: structural bases. Biochem. Mol. Biol. Educ. 31, 228-233.