-
1
-
-
0036817040
-
Epithelial growth factor receptor interacting agents
-
DOI 10.1016/S0889-8588(02)00055-2, PII S0889858802000552
-
J Baselga J Albanell 2002 Epithelial growth factor receptor interacting agents Hematol Oncol Clin North Am 16 1041 1063 12512382 10.1016/S0889-8588(02) 00055-2 (Pubitemid 35462913)
-
(2002)
Hematology/Oncology Clinics of North America
, vol.16
, Issue.5
, pp. 1041-1063
-
-
Baselga, J.1
Albanell, J.2
-
2
-
-
0036362181
-
Why the epidermal growth factor receptor? The rationale for cancer therapy
-
J Baselga 2002 Why the epidermal growth factor receptor? The rationale for cancer therapy Oncologist 7 Suppl 4 2 8 12202782 10.1634/theoncologist.7- suppl-4-2 1:CAS:528:DC%2BD38XnsFOiurw%3D (Pubitemid 34977157)
-
(2002)
Oncologist
, vol.7
, Issue.SUPPL. 4
, pp. 2-8
-
-
Baselga, J.1
-
3
-
-
0028955388
-
Epidermal growth factor-related peptides and their receptors in human malignancies
-
7612182 10.1016/1040-8428(94)00144-I 1:STN:280:DyaK2Mzjs1KgsQ%3D%3D
-
DS Salomon R Brandt F Ciardiello, et al. 1995 Epidermal growth factor-related peptides and their receptors in human malignancies Crit Rev Oncol Hematol 19 183 232 7612182 10.1016/1040-8428(94)00144-I 1:STN:280: DyaK2Mzjs1KgsQ%3D%3D
-
(1995)
Crit Rev Oncol Hematol
, vol.19
, pp. 183-232
-
-
Salomon, D.S.1
Brandt, R.2
Ciardiello, F.3
-
4
-
-
0002823211
-
Cetuximab plus irinotecan is active in CPT-11 refractory colorectal cancer that expresses epidermal growth factor (abstract)
-
Saltz LB RM, Hochester H: Cetuximab plus irinotecan is active in CPT-11 refractory colorectal cancer that expresses epidermal growth factor (abstract). J Clin Oncol. 20, 2001
-
(2001)
J Clin Oncol
, vol.20
-
-
Saltz, L.B.1
Hochester, H.2
-
5
-
-
0001407135
-
Single agent IMC-C225 (Erbitux) has activity in CPT-11 refractory colorectal cancer that expresses epidermal growth factor receptor (abstract)
-
Saltz LB MN, Loeher PJ, et al: Single agent IMC-C225 (Erbitux) has activity in CPT-11 refractory colorectal cancer that expresses epidermal growth factor receptor (abstract). J Clin Oncol 21, 2002
-
(2002)
J Clin Oncol
, vol.21
-
-
Saltz, L.B.1
Loeher, P.J.2
-
6
-
-
3242720345
-
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan- refractory metastatic colorectal cancer
-
DOI 10.1056/NEJMoa033025
-
D Cunningham Y Humblet S Siena, et al. 2004 Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer N Engl J Med 351 337 345 15269313 10.1056/NEJMoa033025 1:CAS:528: DC%2BD2cXlvFGitbk%3D (Pubitemid 38944402)
-
(2004)
New England Journal of Medicine
, vol.351
, Issue.4
, pp. 337-345
-
-
Cunningham, D.1
Humblet, Y.2
Siena, S.3
Khayat, D.4
Bleiberg, H.5
Santoro, A.6
Bets, D.7
Mueser, M.8
Harstrick, A.9
Verslype, C.10
Chau, I.11
Van Cutsem, E.12
-
7
-
-
11344268358
-
Molecular mechanisms of resistance to therapies targeting the epidermal growth factor receptor
-
ER Camp J Summy TW Bauer, et al. 2005 Molecular mechanisms of resistance to therapies targeting the epidermal growth factor receptor Clin Cancer Res 11 397 405 15671571 1:CAS:528:DC%2BD2MXhtVegtbw%3D (Pubitemid 40075820)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.1
, pp. 397-405
-
-
Camp, E.R.1
Summy, J.2
Bauer, T.W.3
Liu, W.4
Gallick, G.E.5
Ellis, L.M.6
-
8
-
-
6344272498
-
ABX-EGF monotherapy in patients (pts) with metastatic colorectal cancer (mCRC): An updated analysis (abstract)
-
Hecht JR PA, Malik I, et al: ABX-EGF monotherapy in patients (pts) with metastatic colorectal cancer (mCRC): an updated analysis (abstract). J Clin Oncol 22, 2004
-
(2004)
J Clin Oncol
, vol.22
-
-
Hecht Jr., P.A.1
Malik, I.2
-
9
-
-
79958063146
-
Panitumumab antitumor activity in patients with metastatic colorectal cancer (mCRC expressing >10% epidermal growth factor receptor (EGFr) (abstract)
-
Berlin J NM, Swanson P, et al: Panitumumab antitumor activity in patients with metastatic colorectal cancer (mCRC expressing >10% epidermal growth factor receptor (EGFr) (abstract).. J Clin Oncol 24, 2006
-
(2006)
J Clin Oncol
, vol.24
-
-
Jnm, B.1
Swanson, P.2
-
10
-
-
34147103678
-
Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy- refractory metastatic colorectal cancer
-
DOI 10.1200/JCO.2006.08.1620
-
E Van Cutsem M Peeters S Siena, et al. 2007 Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer J Clin Oncol 25 13 1658 1664 17470858 10.1200/JCO.2006.08.1620 (Pubitemid 46797944)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.13
, pp. 1658-1664
-
-
Van Cutsem, E.1
Peeters, M.2
Siena, S.3
Humblet, Y.4
Hendlisz, A.5
Neyns, B.6
Canon, J.-L.7
Van Laethem, J.-L.8
Maurel, J.9
Richardson, G.10
Wolf, M.11
Amado, R.G.12
-
11
-
-
34548238762
-
Expression of epiregulin and amphiregulin and K-ras mutation status predict disease control in metastatic colorectal cancer patients treated with cetuximab
-
DOI 10.1200/JCO.2006.10.5437
-
S Khambata-Ford CR Garrett NJ Meropol, et al. 2007 Expression of epiregulin and amphiregulin and K-ras mutation status predict disease control in metastatic colorectal cancer patients treated with cetuximab J Clin Oncol 25 3230 3237 17664471 10.1200/JCO.2006.10.5437 1:CAS:528:DC%2BD2sXhtVWqs7rF (Pubitemid 47325606)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.22
, pp. 3230-3237
-
-
Khambata-Ford, S.1
Garrett, C.R.2
Meropol, N.J.3
Basik, M.4
Harbison, C.T.5
Wu, S.6
Wong, T.W.7
Huang, X.8
Takimoto, C.H.9
Godwin, A.K.10
Tan, B.R.11
Krishnamurthi, S.S.12
Burris III, H.A.13
Poplin, E.A.14
Hidalgo, M.15
Baselga, J.16
Clark, E.A.17
Mauro, D.J.18
-
12
-
-
38649099966
-
KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab
-
DOI 10.1200/JCO.2007.12.5906
-
A Lievre JB Bachet V Boige, et al. 2008 KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab J Clin Oncol 26 374 379 18202412 10.1200/JCO.2007.12.5906 1:CAS:528:DC%2BD1cXitVGntLc%3D (Pubitemid 351171687)
-
(2008)
Journal of Clinical Oncology
, vol.26
, Issue.3
, pp. 374-379
-
-
Lievre, A.1
Bachet, J.-B.2
Boige, V.3
Cayre, A.4
Le Corre, D.5
Buc, E.6
Ychou, M.7
Bouche, O.8
Landi, B.9
Louvet, C.10
Andre, T.11
Bibeau, F.12
Diebold, M.-D.13
Rougier, P.14
Ducreux, M.15
Tomasic, G.16
Emile, J.-F.17
Penault-Llorca, F.18
Laurent-Puig, P.19
-
13
-
-
42649145667
-
Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer
-
18316791 10.1200/JCO.2007.14.7116 1:CAS:528:DC%2BD1cXltlWhsrw%3D The study demonstarted the resistance to anti-EGFR therapy in KRAS mutated mcrc.
-
RG Amado M Wolf M Peeters, et al. 2008 Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer J Clin Oncol 26 1626 1634 18316791 10.1200/JCO.2007.14.7116 1:CAS:528:DC%2BD1cXltlWhsrw%3D The study demonstarted the resistance to anti-EGFR therapy in KRAS mutated mcrc.
-
(2008)
J Clin Oncol
, vol.26
, pp. 1626-1634
-
-
Amado, R.G.1
Wolf, M.2
Peeters, M.3
-
14
-
-
51649120733
-
KRAS status and efficacy in the first-line treatment of patients with metastatic colorectal cancer (mCRC) treated with FOLFIRI with or wihtout cetuximab: The CRYSTAL experience
-
Van Cutsem E LI, D'haens G, Moiseyenko V, Zaluski J, Folprecht G, Tejpar S, et al: KRAS status and efficacy in the first-line treatment of patients with metastatic colorectal cancer (mCRC) treated with FOLFIRI with or wihtout cetuximab: The CRYSTAL experience. J Clin Oncol. 26, 2008.
-
(2008)
J Clin Oncol
, vol.26
-
-
Van Cutsem, E.L.I.1
D'Haens, G.2
Moiseyenko, V.3
Zaluski, J.4
Folprecht, G.5
Tejpar, S.6
-
15
-
-
59949091448
-
Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer
-
19114683 10.1200/JCO.2008.20.8397 1:CAS:528:DC%2BD1MXjsVCjsrk%3D
-
C Bokemeyer I Bondarenko A Makhson, et al. 2009 Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer J Clin Oncol 27 663 671 19114683 10.1200/JCO.2008.20.8397 1:CAS:528:DC%2BD1MXjsVCjsrk%3D
-
(2009)
J Clin Oncol
, vol.27
, pp. 663-671
-
-
Bokemeyer, C.1
Bondarenko, I.2
Makhson, A.3
-
16
-
-
79958047314
-
Randomized phase III study of capecitabine, oxaliplatin, and bevacizumab with or without cetuximab in advanced colrectal cancer (ACC), the CAIRO2 study if the Dutch Colorectal Cancer Group (DCCG)
-
Punt CJTJ, Rodenburg CJ, Cats A, Creemers G, Schrama JG, Erdkamp FL, et al: Randomized phase III study of capecitabine, oxaliplatin, and bevacizumab with or without cetuximab in advanced colrectal cancer (ACC), the CAIRO2 study if the Dutch Colorectal Cancer Group (DCCG). J Clin Oncol. 26, 2008
-
(2008)
J Clin Oncol
, vol.26
-
-
Cjtj, P.1
Rodenburg, C.J.2
Cats, A.3
Creemers, G.4
Schrama, J.G.5
Erdkamp, F.L.6
-
17
-
-
78049341541
-
Association of KRAS p.G13D Mutation with Outcome in Patients with Chemotherapy-Refractory Metastatic Colorectal Cancer Treated with Cetuximab
-
20978259 10.1001/jama.2010.1535
-
W De Roock DJ Jonker F Di Nicolantonio A Sartore-Bianchi 2010 Association of KRAS p.G13D Mutation With Outcome in Patients With Chemotherapy-Refractory Metastatic Colorectal Cancer Treated With Cetuximab JAMA. 304 16 1812 1820 20978259 10.1001/jama.2010.1535
-
(2010)
JAMA.
, vol.304
, Issue.16
, pp. 1812-1820
-
-
De Roock, W.1
Jonker, D.J.2
Di Nicolantonio, F.3
Sartore-Bianchi, A.4
-
18
-
-
57449095367
-
Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer
-
19001320 10.1200/JCO.2008.18.0786 the study showed resistance to anti-EGFR therapy in BRAF mutated mcrc
-
F Di Nicolantonio M Martini F Molinari, et al. 2008 Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer J Clin Oncol 26 5705 5712 19001320 10.1200/JCO.2008.18.0786 the study showed resistance to anti-EGFR therapy in BRAF mutated mcrc
-
(2008)
J Clin Oncol
, vol.26
, pp. 5705-5712
-
-
Di Nicolantonio, F.1
Martini, M.2
Molinari, F.3
-
19
-
-
68749119351
-
KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer
-
19603018 10.1038/sj.bjc.6605177 1:CAS:528:DC%2BD1MXpvFyisb0%3D
-
F Loupakis A Ruzzo C Cremolini, et al. 2009 KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer Br J Cancer 101 715 721 19603018 10.1038/sj.bjc.6605177 1:CAS:528:DC%2BD1MXpvFyisb0%3D
-
(2009)
Br J Cancer
, vol.101
, pp. 715-721
-
-
Loupakis, F.1
Ruzzo, A.2
Cremolini, C.3
-
20
-
-
46349092797
-
Primary resistance to cetuximab therapy in EGFR FISH-positive colorectal cancer patients
-
DOI 10.1038/sj.bjc.6604439, PII 6604439
-
F Cappuzzo M Varella-Garcia 2008 Finocchiaro., Skokan M., Gajapathy S., Primary resistance to cetuximab therapy in EGFR FISH-positive colorectal cancer patients British Journal of cancer 99 83 89 18577988 10.1038/sj.bjc.6604439 1:CAS:528:DC%2BD1cXnvFeru7Y%3D (Pubitemid 351920237)
-
(2008)
British Journal of Cancer
, vol.99
, Issue.1
, pp. 83-89
-
-
Cappuzzo, F.1
Varella-Garcia, M.2
Finocchiaro, G.3
Skokan, M.4
Gajapathy, S.5
Carnaghi, C.6
Rimassa, L.7
Rossi, E.8
Ligorio, C.9
Di Tommaso, L.10
Holmes, A.J.11
Toschi, L.12
Tallini, G.13
Destro, A.14
Roncalli, M.15
Santoro, A.16
Janne, P.A.17
-
21
-
-
78650755609
-
Association of BRAF mutations and EGFR Intron-1 L/L genotype with ersistance to cetuximab plus irinotecan treatment in KRAS wild-type metastatic colorectal cancer patients
-
10.1200/JCO.2008.21.7695 suppl; abstr 4058
-
A Ruzzo C Cremolini F Loupakis D Fornaro B Santini 2009 Association of BRAF mutations and EGFR Intron-1 L/L genotype with ersistance to cetuximab plus irinotecan treatment in KRAS wild-type metastatic colorectal cancer patients J Clin Oncol 27 15s 10.1200/JCO.2008.21.7695 suppl; abstr 4058
-
(2009)
J Clin Oncol
, vol.27
-
-
Ruzzo, A.1
Cremolini, C.2
Loupakis, F.3
Fornaro, D.4
Santini, B.5
-
22
-
-
72449185665
-
The role of KRAS, BRAF, NRAS, and PIK3CA mutations as markers of resistance to cetuximab in chemorefractory metastatic colorectal cancer
-
(May 20 Supplement)
-
Lambrechts W, De Roock H, Prenen J, De Schutter B, Jacobs B, Biesmans B, et al: The role of KRAS, BRAF, NRAS, and PIK3CA mutations as markers of resistance to cetuximab in chemorefractory metastatic colorectal cancer Journal of Clinical Oncology, 2009 ASCO Annual Meeting Proceedings (Post-Meeting Edition). Vol 27, No 15 S (May 20 Supplement), 2009: 4020
-
(2009)
Journal of Clinical Oncology, 2009 ASCO Annual Meeting Proceedings (Post-Meeting Edition)
, vol.27
, Issue.15 S
, pp. 4020
-
-
Lambrechts, W.1
De Roock, H.2
Prenen, J.3
De Schutter, B.4
Jacobs, B.5
Biesmans, B.6
-
23
-
-
77955277111
-
Effects of KRAS, BRAF, NRAS and PIK3CA mutationson the efficacy of cetuximab plus chemotherapy in chemotehrapy-refractory metastatic colorectal cancer: A retropsective consortium analysis
-
20619739 10.1016/S1470-2045(10)70130-3
-
W De Roock B Claes D Bernasconi J De Schutter B Biesmans, et al. 2010 Effects of KRAS, BRAF, NRAS and PIK3CA mutationson the efficacy of cetuximab plus chemotherapy in chemotehrapy-refractory metastatic colorectal cancer: a retropsective consortium analysis Lancet Oncol 11 8 753 762 20619739 10.1016/S1470-2045(10)70130-3
-
(2010)
Lancet Oncol
, vol.11
, Issue.8
, pp. 753-762
-
-
De Roock, W.1
Claes, B.2
Bernasconi, D.3
De Schutter, J.4
Biesmans, B.5
-
24
-
-
78649739337
-
Cetuximab with chemotehrapy (CT) as first-line treatment for metastatic colorectal cancer (mCRC): Analysis of the CRYSTAL and OPUS studies according to KRAS and BRAF mutation status
-
10.1200/JCO.2009.25.9937 This study is the first to demonstrate efficacy of dual targeted therapy in mcrc.
-
C Bokemeyer C Kohne P Rougier C Stroh M Schlichting 2010 Cetuximab with chemotehrapy (CT) as first-line treatment for metastatic colorectal cancer (mCRC): Analysis of the CRYSTAL and OPUS studies according to KRAS and BRAF mutation status J Clin Oncol 28 7s 10.1200/JCO.2009.25.9937 This study is the first to demonstrate efficacy of dual targeted therapy in mcrc.
-
(2010)
J Clin Oncol
, vol.28
-
-
Bokemeyer, C.1
Kohne, C.2
Rougier, P.3
Stroh, C.4
Schlichting, M.5
-
25
-
-
79958057528
-
-
http://www.nelm-web.lbi.co.uk/en/NeLM-Area/News/2009 - -July/01/Phase-III-study-of-sunitinib-Sutent-in-metastatic-colorectal-cancer- discontinued/
-
-
-
-
26
-
-
78649723255
-
PLX4032 in metastatic colorectal cancer patients with mutant BRAF tumors
-
Kopetz S, Desai J, Chan E, Hecht R, O'Dweyer, Lee RJ, et al: PLX4032 in metastatic colorectal cancer patients with mutant BRAF tumors. Abstract 3534 JCO vol 28, No 15 suppl 2010; 3534.
-
Abstract 3534 JCO
, vol.28
, Issue.15 SUPPL. 2010
, pp. 3534
-
-
Kopetz, S.1
Desai, J.2
Chan, E.3
Hecht, R.4
O'Dweyer5
Lee, R.J.6
-
27
-
-
62449302407
-
PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodies
-
19223544 10.1158/0008-5472.CAN-08-2466 1:CAS:528:DC%2BD1MXisFSrt7Y%3D
-
A Sartore-Bianchi M Martini F Molinari, et al. 2009 PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodies Cancer Res 69 1851 1857 19223544 10.1158/0008-5472.CAN-08- 2466 1:CAS:528:DC%2BD1MXisFSrt7Y%3D
-
(2009)
Cancer Res
, vol.69
, pp. 1851-1857
-
-
Sartore-Bianchi, A.1
Martini, M.2
Molinari, F.3
-
28
-
-
14844285975
-
Multicenter phase II study of the oral MEK inhibitor, CI-1040, in patients with advanced non-small-cell lung, breast, colon, and pancreatic cancer
-
DOI 10.1200/JCO.2004.01.185
-
J Rinehart AA Adjei PM Lorusso, et al. 2004 Multicenter phase II study of the oral MEK inhibitor, CL-1040, in patients with advanced non-small cell lung cancer, breast, colon and pancreatic cancer J Clin Oncol 22 4456 4462 15483017 10.1200/JCO.2004.01.185 1:CAS:528:DC%2BD2cXhtFWqt77L (Pubitemid 41185111)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.22
, pp. 4456-4462
-
-
Rinehart, J.1
Adjei, A.A.2
LoRusso, P.M.3
Waterhouse, D.4
Hecht, J.R.5
Natale, R.B.6
Hamid, O.7
Varterasian, M.8
Asbury, P.9
Kaldjian, E.P.10
Gulyas, S.11
Mitchell, D.Y.12
Herrera, R.13
Sebolt-Leopold, J.S.14
Meyer, M.B.15
-
29
-
-
54249155585
-
Heterogeneity of receptor function in colon carcinoma cells determined by cross-talk between type-1 insulin-like growth factor receptor and epidermal growth factor receptor
-
18829558 10.1158/0008-5472.CAN-08-0280 1:CAS:528:DC%2BD1cXhtF2msLrI
-
YP Hu SB Patil M Panasiewicz, et al. 2008 Heterogeneity of receptor function in colon carcinoma cells determined by cross-talk between type-1 insulin-like growth factor receptor and epidermal growth factor receptor Cancer Res 68 8004 8013 18829558 10.1158/0008-5472.CAN-08-0280 1:CAS:528: DC%2BD1cXhtF2msLrI
-
(2008)
Cancer Res
, vol.68
, pp. 8004-8013
-
-
Hu, Y.P.1
Patil, S.B.2
Panasiewicz, M.3
-
30
-
-
77957962308
-
Rnadomized, phase II study of the insulin-like growth factor-1 receptor inhibitor IMC-A12, with ot without cetuximab, in patients with cetuximab- or panitumumab-refractory metastatic colorectal cancer
-
20713879 10.1200/JCO.2010.30.4154 1:CAS:528:DC%2BC3cXhsVSksr7I
-
DL Reidy E Vakiani MG Fakih LB Saltz 2010 Rnadomized, phase II study of the insulin-like growth factor-1 receptor inhibitor IMC-A12, with ot without cetuximab, in patients with cetuximab- or panitumumab-refractory metastatic colorectal cancer J Clin Oncol. 28 27 4240 4246 20713879 10.1200/JCO.2010.30. 4154 1:CAS:528:DC%2BC3cXhsVSksr7I
-
(2010)
J Clin Oncol.
, vol.28
, Issue.27
, pp. 4240-4246
-
-
Reidy, D.L.1
Vakiani, E.2
Fakih, M.G.3
Saltz, L.B.4
-
31
-
-
79958051585
-
A Randomized Phase I/II Trial of AMG 102 or AMG 479 in combination with panitumumab (pmab) compared with pmab alone in patients with wild type KRAS metastatic colorectal cancer: Safety and efficacy results
-
abstr 366
-
VanCutsem E, Eng C, Tabernero J, Nowara E, et al: A Randomized Phase I/II Trial of AMG 102 or AMG 479 in combination with panitumumab (pmab) compared with pmab alone in patients with wild type KRAS metastatic colorectal cancer: Safety and efficacy results. J Clin Oncol 29: 2011 (suppl 4; abstr 366).
-
(2011)
J Clin Oncol
, vol.29
, Issue.SUPPL. 4
-
-
Vancutsem, E.1
Eng, C.2
Tabernero, J.3
Nowara, E.4
-
32
-
-
36048992408
-
Phase II trial of sunitinib in patients with metastatic colorectal cancer after failure of standard therapy
-
DOI 10.1200/JCO.2007.12.8637
-
LB Saltz LS Rosen JL Marshall, et al. 2007 Phase II trial of sunitinib in patients with metastatic colorectal cancer after failure of standard therapy J Clin Oncol 25 4793 4799 17947727 10.1200/JCO.2007.12.8637 1:CAS:528: DC%2BD2sXhtlCgsLbI (Pubitemid 350086483)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.30
, pp. 4793-4799
-
-
Saltz, L.B.1
Rosen, L.S.2
Marshall, J.L.3
Belt, R.J.4
Hurwitz, H.I.5
Eckhardt, S.G.6
Bergsland, E.K.7
Haller, D.G.8
Lockhart, A.C.9
Rocha Lima, C.M.10
Huang, X.11
DePrimo, S.E.12
Chow-Maneval, E.13
Chao, R.C.14
Lenz, H.J.15
-
33
-
-
84872606115
-
A phase 2, randomized, double-blind, placebo-controlled study of hedgehog pathway inhibitor (HPI) GDC-0449 in patients with previously untreated metastatic colorectal cancer (mCRC)
-
abstract
-
Berlin J. A phase 2, randomized, double-blind, placebo-controlled study of hedgehog pathway inhibitor (HPI) GDC-0449 in patients with previously untreated metastatic colorectal cancer (mCRC), abstract ESMO 2010 https://www.webges.com/cslide/library/esmo/mylibrary/search/session/0/509
-
ESMO 2010
-
-
Berlin, J.1
-
34
-
-
3342894130
-
Targeting death receptors in cancer with Apo2L/TRAIL
-
DOI 10.1016/j.coph.2004.02.006, PII S1471489204000840
-
S Kelly A Ashkenazi 2004 Targeting death receptors in cancer with Apo2L/TRAIL Curr Opin Pharmacol 4 333 339 10.1016/j.coph.2004.02.006 (Pubitemid 38987058)
-
(2004)
Current Opinion in Pharmacology
, vol.4
, Issue.4
, pp. 333-339
-
-
Kelley, S.K.1
Ashkenazi, A.2
-
35
-
-
72449176627
-
Fuchs Safety and efficacy of AMG 655 plus modified FOLFOX6 (mFOLFOX6) and bevacizumab (B) for the first-line treatment of patients (pts) with metastatic colorectal cancer (mCRC)
-
10.1200/JCO.2008.21.7695 suppl; abstr 4079
-
L Saltz J Infante L Schwartzberg J Stephenson C Rocha-Lima F Galimi, et al. 2009 Fuchs Safety and efficacy of AMG 655 plus modified FOLFOX6 (mFOLFOX6) and bevacizumab (B) for the first-line treatment of patients (pts) with metastatic colorectal cancer (mCRC) J Clin Oncol 27 15s 10.1200/JCO.2008.21.7695 suppl; abstr 4079
-
(2009)
J Clin Oncol
, vol.27
-
-
Saltz, L.1
Infante, J.2
Schwartzberg, L.3
Stephenson, J.4
Rocha-Lima, C.5
Galimi, F.6
|