Prospective evaluation of the clinical utility of quantitative bleeding severity assessment in patients referred for hemostatic evaluation

Journal of Thrombosis and Haemostasis

Volumn 9, Issue 6, 2011, Pages 1143-1148

  Tosetto, A ^a   Castaman, G ^a   Plug, I ^b   Rodeghiero, F ^a   Eikenboom, J ^c  

^a SAN BORTOLO HOSPITAL   (Italy)

^b Department of Clinical Epidemiology ^*  (Netherlands)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Blood coagulation disorders; Diagnosis; Epidemiology

Indexed keywords

ADOLESCENT; AGED; ARTICLE; BLEEDING; BLOOD CLOTTING DISORDER; BLOOD CLOTTING FACTOR 11 DEFICIENCY; BLOOD GROUP; CHILD; CLINICAL ASSESSMENT TOOL; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE SEVERITY; FAMILY; FEMALE; HEMOPHILIA; HEMOSTASIS; HUMAN; INSTRUMENT; MAJOR CLINICAL STUDY; MALE; MEDICAL HISTORY; MILD BLEEDING DISORDER; PARTIAL THROMBOPLASTIN TIME; PHYSICIAN; PREDICTIVE VALUE; PRESCHOOL CHILD; PREVALENCE; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTHROMBIN TIME; PURPURA; QUANTITATIVE ANALYSIS; RECEIVER OPERATING CHARACTERISTIC; RENDU OSLER WEBER DISEASE; SCHOOL CHILD; SCORING SYSTEM; SENILE PURPURA; SENSITIVITY AND SPECIFICITY; THROMBOCYTE ANOMALY; VON WILLEBRAND DISEASE;

ADOLESCENT; ADULT; AGED; BLOOD PLATELET DISORDERS; CHILD; CHILD, PRESCHOOL; CROSS-SECTIONAL STUDIES; HEMORRHAGE; HEMOSTASIS; HUMANS; MIDDLE AGED; PARTIAL THROMBOPLASTIN TIME; PROSPECTIVE STUDIES; QUESTIONNAIRES; ROC CURVE; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; VON WILLEBRAND DISEASES; YOUNG ADULT;

EID: 79958025563     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2011.04265.x     Document Type: Article

References (22)

1. Rodeghiero F, Tosetto A, Castaman G. How to estimate bleeding risk in mild bleeding disorders. J Thromb Haemost 2007; 5 (Suppl. 1): 157-66.
2. de Wee EM, Mauser-Bunschoten EP, van der BoJ, Degenaar-Dujardin ME, Eikenboom JC, Fijnvandraat K, de Goede-Bolder A, Laros-van Gorkom B, Meijer K, Raat H, Leebeek FW, Win Study Group. Health related quality of life among adult patients with moderate and severe von Willebrand disease. J Thromb Haemost 2010; 8:1492-9.
3. Nieuwenhuis HK, Akkerman JW, Sixma JJ. Patients with a prolonged bleeding time and normal aggregation tests may have storage pool deficiency: studies on one hundred six patients. Blood 1987; 70: 620-3.
4. Rodeghiero F, Castaman G, Dini E. Epidemiological investigation of the prevalence of von Willebrand's disease. Blood 1987; 69: 454-9.
5. Silwer J. von Willebrand's disease in Sweden. Acta Paediatr Scand Suppl 1973; 238: 1-159.
6. Sramek A, Eikenboom JC, Briet E, Vandenbroucke JP, Rosendaal FR. Usefulness of patient interview in bleeding disorders. Arch Intern Med 1995; 155: 1409-15.
7. Wahlberg T, Blomback M, Hall P, Axelsson G. Application of indicators, predictors and diagnostic indices in coagulation disorders. I. Evaluation of a self-administered questionnaire with binary questions. Methods Inf Med 1980; 19: 194-200.
8. Tosetto A, Castaman G, Rodeghiero F. Bleeding scores in inherited bleeding disorders: clinical or research tools? Haemophilia 2008; 14: 415-22.
9. Goodeve A, Eikenboom J, Castaman G, Rodeghiero F, Federici AB, Batlle J, Meyer D, Mazurier C, Goudemand J, Schneppenheim R, Budde U, Ingerslev J, Habart D, Vorlova Z, Holmberg L, Lethagen S, Pasi J, Hill F. Phenotype and genotype of a cohort of families historically diagnosed with type 1 von Willebrand disease in the European study, Molecular and Clinical Markers for the Diagnosis and Management of Type 1 von Willebrand Disease (MCMDM-1VWD). Blood 2007; 109: 112-21.
10. Biss TT, Blanchette VS, Clark DS, Bowman M, Wakefield CD, Silva M, Lillicrap D, James PD, Rand ML. Quantitation of bleeding symptoms in children with von Willebrand disease: use of a standardized pediatric bleeding questionnaire. J Thromb Haemost 2010; 8: 950-6.
11. Tosetto A, Rodeghiero F, Castaman G, Goodeve A, Federici AB, Battle J, Meyer D, Fressinaud E, Mazurier C, Goudemand J, Eikenboom JC, Schneppenheim R, Budde U, Ingerslev J, Vorlova Z, Habart D, Holmberg L. A quantitative analysis of bleeding symptoms in type 1 von Willebrand disease: results from a multicenter European study (MCMDM-1 VWD). J Thromb Haemost 2006; 4: 766-73.
12. Bowman M, Mundell G, Grabell J, Hopman WM, Rapson D, Lillicrap D, James P. Generation and validation of the Condensed MCMDM-1VWD Bleeding Questionnaire for von Willebrand disease. J Thromb Haemost 2008; 6: 2062-6.
13. Rodeghiero F, Castaman G, Tosetto A, Battle J, Baudo F, Cappelletti A, Casana P, De Bosch N, Eikenboom JC, Federici AB, Lethagen S, Linari S, Srivastava A. The discriminant power of bleeding history for the diagnosis of von Willebrand disease type 1: an international, multicenter study. J Thromb Haemost 2005; 3: 2619-26.
14. Pepe M. The Statistical Evaluation of Medical Tests for Classification and Prediction. Oxford: Oxford University Press, 2003.
15. Weiss KM. Genetic Variation and Human Disease. Cambridge: Cambridge University Press, 1993.
16. StataCorp. Stata Statistical Software: Release 11.0. College Station, TX: Stata Corporation, 2010.
17. Shaw PH, Reynolds S, Gunawardena S, Krishnamurti L, Ritchey AK. The prevalence of bleeding disorders among healthy pediatric patients with abnormal preprocedural coagulation studies. J Pediatr Hematol Oncol 2008; 30: 135-41.
18. Watson HG, Greaves M. Can we predict bleeding? Semin Thromb Hemost 2008; 34: 97-103.
19. Sadler J, Rodeghiero F. Provisional criteria for the diagnosis of VWD type 1; on behalf of the SSC Subcommittee on von Willebrand factor. J Thromb Haemost 2005; 3: 775-7.
20. Quiroga T, Goycoolea M, Panes O, Aranda E, Martinez C, Belmont S, Munoz B, Zuniga P, Pereira J, Mezzano D. High prevalence of bleeders of unknown cause among patients with inherited mucocutaneous bleeding. A prospective study of 280 patients and 299 controls. Haematologica 2007; 92: 357-65.
21. Marcus PD, Nire KG, Grooms L, Klima J, O'Brien SH. The power of a standardized bleeding score in diagnosing paediatric type 1 von Willebrand's disease and platelet function defects. Haemophilia 2011;17: 223-7.
22. Rodeghiero F, Tosetto A, Abshire T, Arnold DM, Coller B, James P, Neunert C, Lillicrap D; Group ft. ISTH/SSC bleeding assessment tool: a standardized questionnaire and a proposal for a new bleeding score for inherited bleeding disorders. J Thromb Haemost 2010; 8:2063-5.