Distinctive TLR7 signaling, type I IFN production, and attenuated innate and adaptive immune responses to yellow fever virus in a primate reservoir host

Journal of Immunology

Volumn 186, Issue 11, 2011, Pages 6406-6416

  Mandl, Judith N ^a,b,c   Akondy, Rama ^b   Lawson, Benton ^b   Kozyr, Natalia ^b   Staprans, Silvija I ^b,d   Ahmed, Rafi ^b   Feinberg, Mark B ^b  

^a EMORY UNIVERSITY   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^d MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; CHEMOKINE RECEPTOR CCR7; TOLL LIKE RECEPTOR 7; VIRUS RNA; YELLOW FEVER VACCINE;

ADAPTIVE IMMUNITY; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIGEN RECOGNITION; ARTICLE; CERCOCEBUS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE CARRIER; EX VIVO STUDY; HUMAN; HUMAN CELL; IMMUNOGENICITY; INNATE IMMUNITY; LENTIVIRUS INFECTION; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PLASMACYTOID DENDRITIC CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHESUS MONKEY; SIMIAN IMMUNODEFICIENCY VIRUS INFECTION; SPECIES COMPARISON; T LYMPHOCYTE ACTIVATION; VIRUS CELL INTERACTION; VIRUS IMMUNITY; YELLOW FEVER; YELLOW FEVER FLAVIVIRUS;

ADAPTIVE IMMUNITY; ANIMALS; ANTIBODIES, VIRAL; CELL LINE; CELLS, CULTURED; CERCOCEBUS ATYS; DENDRITIC CELLS; DISEASE RESERVOIRS; FLOW CYTOMETRY; HUMANS; IMMUNITY, INNATE; INTERFERON-ALPHA; KINETICS; LEUKOCYTES, MONONUCLEAR; MACACA MULATTA; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 9; VACCINIA VIRUS; YELLOW FEVER; YELLOW FEVER VACCINE; YELLOW FEVER VIRUS;

EID: 79958024954     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1001191     Document Type: Article

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