Acute aldicarb toxicity in dogs: 15 cases (2001-2009)

Journal of Veterinary Emergency and Critical Care

Volumn 21, Issue 3, 2011, Pages 253-260

  Anastasio, John D ^a   Sharp, Claire R ^b  

^a ANIMAL MEDICAL CENTER   (United States)

^b TUFTS UNIVERSITY   (United States)

Author keywords

Carbamate; Rodenticide; Tremors; Tres pasitos; Vomiting

Indexed keywords

ALDICARB; INSECTICIDE; LACTIC ACID DERIVATIVE;

ANIMAL; ANIMAL DISEASE; ARTICLE; BLOOD; BLOOD GAS ANALYSIS; CHEMICALLY INDUCED DISORDER; DOG; DOG DISEASE; HOSPITAL; RETROSPECTIVE STUDY; TREATMENT OUTCOME; UNITED STATES;

ALDICARB; ANIMALS; BLOOD GAS ANALYSIS; DOG DISEASES; DOGS; HOSPITALS, ANIMAL; INSECTICIDES; LACTATES; MASSACHUSETTS; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

ANIMALIA; CANIS FAMILIARIS;

EID: 79958015692     PISSN: 14793261     EISSN: 14764431     Source Type: Journal    
DOI: 10.1111/j.1476-4431.2011.00613.x     Document Type: Article

References (45)

1. Baron RL. Carbamate insecticides, In: Hayes WJ Jr, Laws ER Jr. eds. Handbook of Pesticide Toxicology. San Diego: Academic Press; 1991, pp. 3-6.
2. Nelson LS, Perrone J, DeRoos F, et al. Aldicarb poisoning by an illicit rodenticide imported into the United States: Tres Pasitos. J Toxicol Clin Toxicol 2001; 39 (5):447-452.
3. Centers-for-Disease-Control. Poisonings Associated with Illegal Use of Aldicarb as a Rodenticide - New York City. New York City: MMWR; 1997, pp. 961-963.
4. Risher JF, Mink FL, Stara JF. The toxicologic effects of the carbamate insecticide aldicarb in mammals: a review. Environ Health Perspect 1987; 72:267-281.
5. Baron RL. A carbamate insecticide: a case study of aldicarb. Environ Health Perspect 1994; 102 (suppl 11):23-27.
6. Vates C, Osterhoudt KC. Give me three steps. Pediatr Emerg Care 2008; 24 (6):389-391.
7. Ford MD. Clinical Toxicology, 1st edn. Philadelphia: WB Saunders Co; 2001.
8. Hayes AW. Principles and Methods of Toxicology, 5th edn. Boca Raton: CRC Press; 2008.
9. Tsao TC, Juang YC, Lan RS, et al. Respiratory failure of acute organophosphate and carbamate poisoning. Chest 1990; 98 (3):631-636.
10. Guitart R, Sachana M, Caloni F, et al. Animal poisoning in Europe. Part 3: wildlife. Vet J 2009; 183 (3):260-265.
11. McEntee K, Poncelet L, Clercx C, et al. Acute polymyopathy after carbamate poisoning in a dog. Vet Rec 1994; 135:88-90.
12. Galtarossa FX, Righi DA, de Souza Spinosa H. Toxicology of the pesticide aldicarb ('BB'): general aspects, clinical and therapeutic in dogs and cats. Cienc Rural 2007; 37 (4):1206-1211.
13. Frazier K, Hullinger G, Hines M II, et al. 162 cases of aldicarb intoxication in Georgia domestic animals from 1988-1998. Vet Hum Toxicol 1999; 41 (4):233-235.
14. Guitart R, Manosa S, Guerrero X, et al. Animal poisonings: the 10-year experience of a veterinary analytical toxicology laboratory. Vet Hum Toxicol 1999; 41 (5):331-335.
15. Berny P, Caloni F, Croubels S, et al. Animal poisoning in Europe. Part 2: companion animals. Vet J 2009; 183 (3):255-259.
16. Guitart R, Croubels S, Caloni F, et al. Animal poisoning in Europe. Part 1: farm livestock and poultry. Vet J 2009; 183 (3):249-254.
17. Motas-Guzman M, Marla-Mojica P, Romero D, et al. Intentional poisoning of animals in southeastern Spain: a review of the veterinary toxicology service from Murcia, Spain. Vet Hum Toxicol 2003; 45 (1):47-50.
18. Xavier FG, Righi DA, Florio JC, et al. Thin-layer chromatography for aldicarb diagnosis in dogs and cats. Arq Bras Med Vet Zootec 2007; 59 (5):1231-1235.
19. Leibson T, Lifshitz M. Organophosphate and carbamate poisoning: review of the current literature and summary of clinical and laboratory experience in southern Israel. Isr Med Assoc J 2008; 10 (11):767-770.
20. Guyton AC The autonomic nervous system and the adrenal medulla, In: Guyton AC, Hall JE. eds. Textbook of Medical Physiology, 11th edn. Philadelphia: Elsevier Saunders; 2006, pp. 750-751.
21. Tracqui A, Flesch F, Sauder P, et al. Repeated measurements of aldicarb in blood and urine in a case of nonfatal poisoning. Hum Exp Toxicol 2001; 20 (12):657-660.
22. Bardin PG, van Eden SF, Moolman JA, et al. Organophosphate and carbamate poisoning. Arch Intern Med 1994; 154:1433-1441.
23. Saadeh AM, Farsakh NA, al-Ali MK. Cardiac manifestations of acute carbamate and organophosphate poisoning. Heart 1997; 77 (5):461-464.
24. Verster RS, Botha CJ, Naidoo V, et al. Aldicarb poisoning of dogs and cats in Gauteng during 2003. J S Afr Vet Assoc 2004; 75 (4):177-181.
25. Galtarossa FX, Righi DA, de Souza Spinosa H. Fatal poisonings in dogs and cats: a 6-year report in a veterinary pathology service. Braz J Vet Res Anim Sci 2007; 44 (4):304-309.
26. Udall ND. The toxicity of the molluscicides metaldehyde and methiocarb to dogs. Vet Rec 1973; 93 (15):420-422.
27. Studdert VP. Epidemiologic features of snail and slug bait poisoning in dogs and cats. Aust Vet J 1985; 62 (8):269-271.
28. Firth AM. Treatment of snail bait toxicity in dogs: retrospective study of 56 cases. J Vet Emerg Crit Care 1992; 2 (1):31-36.
29. Corfield GS, Connor LM, Swindells KL, et al. Intussusception following methiocarb toxicity in three dogs. J Vet Emerg Crit Care 2008; 18 (1):68-74.
30. Peterson ME. Organophosphate and carbamate insecticides, In: Peterson ME. ed. Small Animal Toxicology, 2nd edn. St. Louis: Elsevier Saunders; 2006, pp. 941-955.
31. Norsworthy GD. Toxicosis by organophosphates and carbamates, In: Norsworthy GD, Crystal M, Fooshee-Grace S, Tilley LP. eds. The Feline Patient, 3rd edn. Ames: Blackwell Publishing; 2004, pp. 216-217.
32. Meller D, Fraser I, Kryger M. Hyperglycemia in anticholinesterase poisoning. Can Med Assoc J 1981; 124 (6):745-748.
33. Jovic RC. Correlation between signs of toxicity and some biochemical changes in rats poisoned by soman. Eur J Pharmacol 1974; 25 (2):159-164.
34. Firth AM. Treatment of snail bait toxicity in dogs: literature review - Part 1. J Vet Emerg Crit Care 1992; 2 (1):25-30.
35. Fikes JD. Toxicology of selected pesticides, drugs, and chemicals organophosphorus and carbamate insecticides. Vet Clin North Am Small Anim Pract 1990; 20 (2):353-367.
36. Howland MA. Antidotes in depth - pralidoxime, In: Flomenbaum NE, Goldfrank LR, Hoffman RS. eds. Goldfrank's Toxicologic Emergencies, 8th edn. New York: McGraw-Hill; 2006, pp. 1513-1518.
37. Clemmons RM, Meyer DJ, Sundlof SF, et al. Correction of organophosphate-induced neuromuscular blockade by diphenhydramine. Am J Vet Res 1984; 45 (10):2167-2169.
38. Eyer P. The role of oximes in the management of organophosphorus pesticide poisoning. Toxicol Rev 2003; 22 (3):165-190.
39. Harris LW, Talbot BG, Lennox WJ, et al. The relationship between oxime-induced reactivation of carbamylated acetylcholinesterase and antidotal efficacy against carbamate intoxication. Toxicol Appl Pharmacol 1989; 98 (1):128-133.
40. Lieske CN, Clark JH, Maxwell DM, et al. Studies of the amplification of carbaryl toxicity by various oximes. Toxicol Lett 1992; 62 (2-3):127-137.
41. Natoff IL, Reiff B. Effect of oximes on the acute toxicity of anticholinesterase carbamates. Toxicol Appl Pharmacol 1973; 25 (4):569-575.
42. Mercurio-Zappala M, Hack JB, Salvador A, et al. Pralidoxime in carbaryl poisoning: an animal model. Hum Exp Toxicol 2007; 26 (2):125-129.
43. Burgess JL, Bernstein JN, Hurlbut K. Aldicarb poisoning. A case report with prolonged cholinesterase inhibition and improvement after pralidoxime therapy. Arch Intern Med 1994; 154 (2):221-224.
44. Ekins BR, Geller RJ. Methomyl-induced carbamate poisoning treated with pralidoxime chloride. West J Med 1994; 161 (1):68-70.
45. Kassa J. Review of oximes in the antidotal treatment of poisoning by organophosphorus nerve agents. J Toxicol Clin Toxicol 2002; 40 (6):803-816.