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Volumn 106, Issue 1, 2011, Pages 315-322

Intergenerational transmission of insulin resistance and type 2 diabetes

Author keywords

Animal model; Developmental programming; Hypothalamus; Type 2 DM

Indexed keywords

CHILD; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; HYPOTHALAMUS; INSULIN RESISTANCE; METABOLISM; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PHYSIOLOGY; PREGNANCY; PREGNANCY DIABETES MELLITUS; REVIEW;

EID: 79958010829     PISSN: 00796107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbiomolbio.2010.11.011     Document Type: Review
Times cited : (44)

References (80)
  • 1
    • 51349085004 scopus 로고    scopus 로고
    • Developmental origins of disease and determinants of chromatin structure: maternal diet modifies the primate fetal epigenome
    • Aagard-Tillery K.M., Grove K., Bishop J., Ke X., Fu Q., McKnight R., Lane R.H. Developmental origins of disease and determinants of chromatin structure: maternal diet modifies the primate fetal epigenome. J. Mol. Endocrinol. 2008, 2008:91-102.
    • (2008) J. Mol. Endocrinol. , vol.2008 , pp. 91-102
    • Aagard-Tillery, K.M.1    Grove, K.2    Bishop, J.3    Ke, X.4    Fu, Q.5    McKnight, R.6    Lane, R.H.7
  • 2
    • 0025670655 scopus 로고
    • Maternal diabetes during pregnancy: consequences for the offspring
    • Aerts L., Holemans K., Van Assche F.A. Maternal diabetes during pregnancy: consequences for the offspring. Diabetes Metab. Rev. 1990, 6:147-167.
    • (1990) Diabetes Metab. Rev. , vol.6 , pp. 147-167
    • Aerts, L.1    Holemans, K.2    Van Assche, F.A.3
  • 3
    • 0024262646 scopus 로고
    • The diabetic intrauterine milieu has a long-lasting effect on insulin secretion by B cells and on insulin uptake by target tissues
    • Aerts L., Sodoyez-Goffaux F., Sodoyez J.C., Malaisse W.J., Van Assche F.A. The diabetic intrauterine milieu has a long-lasting effect on insulin secretion by B cells and on insulin uptake by target tissues. Am. J. Obstet. Gynecol. 1988, 159:1287-1292.
    • (1988) Am. J. Obstet. Gynecol. , vol.159 , pp. 1287-1292
    • Aerts, L.1    Sodoyez-Goffaux, F.2    Sodoyez, J.C.3    Malaisse, W.J.4    Van Assche, F.A.5
  • 4
    • 0032032575 scopus 로고    scopus 로고
    • Postnatal leptin surge and regulation of circadian rhythm of leptin by feeding. Implications for energy homeostasis and neuroendocrine function
    • Ahima R.S., Prabakaran D., Flier J.S. Postnatal leptin surge and regulation of circadian rhythm of leptin by feeding. Implications for energy homeostasis and neuroendocrine function. J. Clin. Invest. 1998, 101:1020-1027.
    • (1998) J. Clin. Invest. , vol.101 , pp. 1020-1027
    • Ahima, R.S.1    Prabakaran, D.2    Flier, J.S.3
  • 5
    • 75149180515 scopus 로고    scopus 로고
    • Standards of medical care in diabetes-2010
    • American Diabetes Association
    • Standards of medical care in diabetes-2010. Diabetes Care 2010, 33(Suppl. 1):S11-S61. American Diabetes Association.
    • (2010) Diabetes Care , vol.33 , Issue.SUPPL. 1
  • 6
    • 0036319367 scopus 로고    scopus 로고
    • Gestational diabetes leads to the development of diabetes in adulthood in the rat
    • Boloker J., Gertz S.J., Simmons R.A. Gestational diabetes leads to the development of diabetes in adulthood in the rat. Diabetes 2002, 51:1499-1506.
    • (2002) Diabetes , vol.51 , pp. 1499-1506
    • Boloker, J.1    Gertz, S.J.2    Simmons, R.A.3
  • 7
    • 77649200393 scopus 로고    scopus 로고
    • Development of hypothalamic neural networks controlling appetite
    • Bouret S.G. Development of hypothalamic neural networks controlling appetite. Forum Nutr. 2010, 63:84-93.
    • (2010) Forum Nutr. , vol.63 , pp. 84-93
    • Bouret, S.G.1
  • 8
    • 1842536210 scopus 로고    scopus 로고
    • Trophic action of leptin on hypothalamic neurons that regulate feeding
    • Bouret S.G., Draper S.J., Simerly R.B. Trophic action of leptin on hypothalamic neurons that regulate feeding. Science 2004, 304:108-110.
    • (2004) Science , vol.304 , pp. 108-110
    • Bouret, S.G.1    Draper, S.J.2    Simerly, R.B.3
  • 9
    • 38749135486 scopus 로고    scopus 로고
    • Hypothalamic neural projections are permanently disrupted in diet-induced obese rats
    • Bouret S.G., Gorski J.N., Patterson C.M., Levin B.E., Simerly R.B. Hypothalamic neural projections are permanently disrupted in diet-induced obese rats. Cell Metab. 2008, 7:179-185.
    • (2008) Cell Metab. , vol.7 , pp. 179-185
    • Bouret, S.G.1    Gorski, J.N.2    Patterson, C.M.3    Levin, B.E.4    Simerly, R.B.5
  • 10
    • 33745668478 scopus 로고    scopus 로고
    • SiRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle
    • Bouzakri K., Zachrisson A., Al-Khalili L., Zhang B.B., Koistinen H.A., Krook A., Zierath J.R. siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle. Cell Metab. 2006, 4:89-96.
    • (2006) Cell Metab. , vol.4 , pp. 89-96
    • Bouzakri, K.1    Zachrisson, A.2    Al-Khalili, L.3    Zhang, B.B.4    Koistinen, H.A.5    Krook, A.6    Zierath, J.R.7
  • 12
    • 77953951788 scopus 로고    scopus 로고
    • High fat programming of beta-cell failure
    • Cerf M.E. High fat programming of beta-cell failure. Adv. Exp. Med. Biol. 2010, 654:77-89.
    • (2010) Adv. Exp. Med. Biol. , vol.654 , pp. 77-89
    • Cerf, M.E.1
  • 13
    • 71849106198 scopus 로고    scopus 로고
    • Gestational high-fat programming impairs insulin release and reduces Pdx-1 and glucokinase immunoreactivity in neonatal Wistar rats
    • Cerf M.E., Chapman C.S., Muller C.J., Louw J. Gestational high-fat programming impairs insulin release and reduces Pdx-1 and glucokinase immunoreactivity in neonatal Wistar rats. Metabolism 2009, 58:1787-1792.
    • (2009) Metabolism , vol.58 , pp. 1787-1792
    • Cerf, M.E.1    Chapman, C.S.2    Muller, C.J.3    Louw, J.4
  • 14
    • 77951981051 scopus 로고    scopus 로고
    • High fat programming induces glucose intolerance in weanling Wistar rats
    • Cerf M.E., Louw J. High fat programming induces glucose intolerance in weanling Wistar rats. Horm. Metab. Res. 2010, 42:307-310.
    • (2010) Horm. Metab. Res. , vol.42 , pp. 307-310
    • Cerf, M.E.1    Louw, J.2
  • 15
    • 58149336861 scopus 로고    scopus 로고
    • Maternal high-fat diet and fetal programming: increased proliferation of hypothalamic peptide-producing neurons that increase risk for overeating and obesity
    • Chang G.Q., Gaysinskaya V., Karatayev O., Leibowitz S.F. Maternal high-fat diet and fetal programming: increased proliferation of hypothalamic peptide-producing neurons that increase risk for overeating and obesity. J. Neurosci. 2008, 28:12107-12119.
    • (2008) J. Neurosci. , vol.28 , pp. 12107-12119
    • Chang, G.Q.1    Gaysinskaya, V.2    Karatayev, O.3    Leibowitz, S.F.4
  • 16
    • 38949211488 scopus 로고    scopus 로고
    • High prevalence of type 2 diabetes and pre-diabetes in adult offspring of women with gestational diabetes mellitus or type 1 diabetes: the role of intrauterine hyperglycemia
    • Clausen T.D., Mathiesen E.R., Hansen T., Pedersen O., Jensen D.M., Lauenborg J., Damm P. High prevalence of type 2 diabetes and pre-diabetes in adult offspring of women with gestational diabetes mellitus or type 1 diabetes: the role of intrauterine hyperglycemia. Diabetes Care 2008, 31:340-346.
    • (2008) Diabetes Care , vol.31 , pp. 340-346
    • Clausen, T.D.1    Mathiesen, E.R.2    Hansen, T.3    Pedersen, O.4    Jensen, D.M.5    Lauenborg, J.6    Damm, P.7
  • 17
    • 39049172652 scopus 로고    scopus 로고
    • Isoform-specific defects of insulin stimulation of Akt/protein kinase B (PKB) in skeletal muscle cells from type 2 diabetic patients
    • Cozzone D., Frojdo S., Disse E., Debard C., Laville M., Pirola L., Vidal H. Isoform-specific defects of insulin stimulation of Akt/protein kinase B (PKB) in skeletal muscle cells from type 2 diabetic patients. Diabetologia 2008, 51:512-521.
    • (2008) Diabetologia , vol.51 , pp. 512-521
    • Cozzone, D.1    Frojdo, S.2    Disse, E.3    Debard, C.4    Laville, M.5    Pirola, L.6    Vidal, H.7
  • 19
    • 20444442419 scopus 로고    scopus 로고
    • Effect of treatment of gestational diabetes mellitus on pregnancy outcomes
    • G. the Australian Carbohydrate Intolerance Study in Pregnant Women Trial
    • Crowther C.A., Hiller J.E., Moss J.R., McPhee A.J., Jeffries W.S., Robinson J.S., G. the Australian Carbohydrate Intolerance Study in Pregnant Women Trial Effect of treatment of gestational diabetes mellitus on pregnancy outcomes. N. Engl. J. Med. 2005, 352:2477-2486.
    • (2005) N. Engl. J. Med. , vol.352 , pp. 2477-2486
    • Crowther, C.A.1    Hiller, J.E.2    Moss, J.R.3    McPhee, A.J.4    Jeffries, W.S.5    Robinson, J.S.6
  • 20
    • 34447121212 scopus 로고    scopus 로고
    • The predisposition to obesity and diabetes in offspring of diabetic mothers
    • Dabelea D. The predisposition to obesity and diabetes in offspring of diabetic mothers. Diabetes Care 2007, 30(Suppl. 2):S169-S174.
    • (2007) Diabetes Care , vol.30 , Issue.SUPPL. 2
    • Dabelea, D.1
  • 23
    • 0034794325 scopus 로고    scopus 로고
    • Intrauterine diabetic environment confers risks for type 2 diabetes mellitus and obesity in the offspring, in addition to genetic susceptibility
    • Dabelea D., Pettitt D.J. Intrauterine diabetic environment confers risks for type 2 diabetes mellitus and obesity in the offspring, in addition to genetic susceptibility. J. Pediatr. Endocrinol. Metab. 2001, 14:1085-1091.
    • (2001) J. Pediatr. Endocrinol. Metab. , vol.14 , pp. 1085-1091
    • Dabelea, D.1    Pettitt, D.J.2
  • 24
    • 0016812904 scopus 로고
    • On possible genetic and epigenetic modes of diabetes transmission
    • Dorner G., Mohnike A., Steindel E. On possible genetic and epigenetic modes of diabetes transmission. Endokrinologie 1975, 66:225-227.
    • (1975) Endokrinologie , vol.66 , pp. 225-227
    • Dorner, G.1    Mohnike, A.2    Steindel, E.3
  • 25
    • 70350313230 scopus 로고    scopus 로고
    • Maternal high-fat diet promotes body length increases and insulin insensitivity in second-generation mice
    • Dunn G.A., Bale T.L. Maternal high-fat diet promotes body length increases and insulin insensitivity in second-generation mice. Endocrinology 2009, 150:4999-5009.
    • (2009) Endocrinology , vol.150 , pp. 4999-5009
    • Dunn, G.A.1    Bale, T.L.2
  • 26
    • 1542347160 scopus 로고    scopus 로고
    • Cross-fostering to diabetic rat dams affects early development of mediobasal hypothalamic nuclei regulating food intake, body weight, and metabolism
    • Fahrenkrog S., Harder T., Stolaczyk E., Melchior K., Franke K., Dudenhausen J.W., Plagemann A. Cross-fostering to diabetic rat dams affects early development of mediobasal hypothalamic nuclei regulating food intake, body weight, and metabolism. J. Nutr. 2004, 134:648-654.
    • (2004) J. Nutr. , vol.134 , pp. 648-654
    • Fahrenkrog, S.1    Harder, T.2    Stolaczyk, E.3    Melchior, K.4    Franke, K.5    Dudenhausen, J.W.6    Plagemann, A.7
  • 28
    • 0026333053 scopus 로고
    • Insulin secretion in adult rats after intrauterine exposure to mild hyperglycemia during late gestation
    • Gauguier D., Bihoreau M.T., Picon L., Ktorza A. Insulin secretion in adult rats after intrauterine exposure to mild hyperglycemia during late gestation. Diabetes 1991, 40(Suppl. 2):109-114.
    • (1991) Diabetes , vol.40 , Issue.SUPPL. 2 , pp. 109-114
    • Gauguier, D.1    Bihoreau, M.T.2    Picon, L.3    Ktorza, A.4
  • 30
    • 4544301144 scopus 로고    scopus 로고
    • Type 2 diabetes mellitus-genes or intrauterine environment? An embryo transfer paradigm in rats
    • Gill-Randall R., Adams D., Ollerton R.L., Lewis M., Alcolado J.C. Type 2 diabetes mellitus-genes or intrauterine environment? An embryo transfer paradigm in rats. Diabetologia 2004, 47:1354-1359.
    • (2004) Diabetologia , vol.47 , pp. 1354-1359
    • Gill-Randall, R.1    Adams, D.2    Ollerton, R.L.3    Lewis, M.4    Alcolado, J.C.5
  • 33
    • 77950216899 scopus 로고    scopus 로고
    • Changes in melanocortin expression and inflammatory pathways in fetal offspring of nonhuman primates fed a high-fat diet
    • Grayson B.E., Levasseur P.R., Williams S.M., Smith M.S., Marks D.L., Grove K.L. Changes in melanocortin expression and inflammatory pathways in fetal offspring of nonhuman primates fed a high-fat diet. Endocrinology 2010, 151:1622-1632.
    • (2010) Endocrinology , vol.151 , pp. 1622-1632
    • Grayson, B.E.1    Levasseur, P.R.2    Williams, S.M.3    Smith, M.S.4    Marks, D.L.5    Grove, K.L.6
  • 34
    • 0038043228 scopus 로고    scopus 로고
    • Ontogeny of the hypothalamic neuropeptide Y system
    • Grove K.L., Smith M.S. Ontogeny of the hypothalamic neuropeptide Y system. Physiol. Behav. 2003, 79:47-63.
    • (2003) Physiol. Behav. , vol.79 , pp. 47-63
    • Grove, K.L.1    Smith, M.S.2
  • 36
    • 30044439528 scopus 로고    scopus 로고
    • Developmental programming of the hypothalamus: a matter of fat
    • Horvath T.L., Bruning J.C. Developmental programming of the hypothalamus: a matter of fat. Nat. Med. 2006, 12:52-53.
    • (2006) Nat. Med. , vol.12 , pp. 52-53
    • Horvath, T.L.1    Bruning, J.C.2
  • 37
    • 34250011188 scopus 로고    scopus 로고
    • The increasing prevalence of diabetes in pregnancy
    • vii
    • Hunt K.J., Schuller K.L. The increasing prevalence of diabetes in pregnancy. Obstet. Gynecol. Clin. North Am. 2007, 34:173-199. vii.
    • (2007) Obstet. Gynecol. Clin. North Am. , vol.34 , pp. 173-199
    • Hunt, K.J.1    Schuller, K.L.2
  • 39
    • 77958166094 scopus 로고    scopus 로고
    • Animal models in diabetes and pregnancy
    • Jawerbaum A., White V. Animal models in diabetes and pregnancy. Endocr. Rev. 2010.
    • (2010) Endocr. Rev.
    • Jawerbaum, A.1    White, V.2
  • 40
    • 57649238863 scopus 로고    scopus 로고
    • Fetal programming of glucose-insulin metabolism
    • Jones R.H., Ozanne S.E. Fetal programming of glucose-insulin metabolism. Mol. Cell Endocrinol. 2009, 297:4-9.
    • (2009) Mol. Cell Endocrinol. , vol.297 , pp. 4-9
    • Jones, R.H.1    Ozanne, S.E.2
  • 43
    • 75149140138 scopus 로고    scopus 로고
    • Intrauterine exposure to maternal diabetes is associated with higher adiposity and insulin resistance and clustering of cardiovascular risk markers in Indian children
    • Krishnaveni G.V., Veena S.R., Hill J.C., Kehoe S., Karat S.C., Fall C.H. Intrauterine exposure to maternal diabetes is associated with higher adiposity and insulin resistance and clustering of cardiovascular risk markers in Indian children. Diabetes Care 2010, 33:402-404.
    • (2010) Diabetes Care , vol.33 , pp. 402-404
    • Krishnaveni, G.V.1    Veena, S.R.2    Hill, J.C.3    Kehoe, S.4    Karat, S.C.5    Fall, C.H.6
  • 51
    • 67349223615 scopus 로고    scopus 로고
    • Established diet-induced obesity in female rats leads to offspring hyperphagia, adiposity and insulin resistance
    • Nivoit P., Morens C., Van Assche F.A., Jansen E., Poston L., Remacle C., Reusens B. Established diet-induced obesity in female rats leads to offspring hyperphagia, adiposity and insulin resistance. Diabetologia 2009, 52:1133-1142.
    • (2009) Diabetologia , vol.52 , pp. 1133-1142
    • Nivoit, P.1    Morens, C.2    Van Assche, F.A.3    Jansen, E.4    Poston, L.5    Remacle, C.6    Reusens, B.7
  • 53
    • 45549097738 scopus 로고    scopus 로고
    • Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1
    • Park J.H., Stoffers D.A., Nicholls R.D., Simmons R.A. Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1. J. Clin. Invest. 2008, 118:2316-2324.
    • (2008) J. Clin. Invest. , vol.118 , pp. 2316-2324
    • Park, J.H.1    Stoffers, D.A.2    Nicholls, R.D.3    Simmons, R.A.4
  • 54
    • 77249156816 scopus 로고    scopus 로고
    • Metabolic programming due to alterations in nutrition in the immediate postnatal period
    • Patel M.S., Srinivasan M. Metabolic programming due to alterations in nutrition in the immediate postnatal period. J. Nutr. 2010, 140:658-661.
    • (2010) J. Nutr. , vol.140 , pp. 658-661
    • Patel, M.S.1    Srinivasan, M.2
  • 55
    • 77956046109 scopus 로고    scopus 로고
    • Large litter rearing enhances leptin sensitivity and protects selectively bred diet-induced obese rats from becoming obese
    • Patterson C.M., Bouret S.G., Park S., Irani B.G., Dunn-Meynell A.A., Levin B.E. Large litter rearing enhances leptin sensitivity and protects selectively bred diet-induced obese rats from becoming obese. Endocrinology 2010, 151:4270-4279.
    • (2010) Endocrinology , vol.151 , pp. 4270-4279
    • Patterson, C.M.1    Bouret, S.G.2    Park, S.3    Irani, B.G.4    Dunn-Meynell, A.A.5    Levin, B.E.6
  • 57
    • 28444467763 scopus 로고    scopus 로고
    • Perinatal programming and functional teratogenesis: impact on body weight regulation and obesity
    • Plagemann A. Perinatal programming and functional teratogenesis: impact on body weight regulation and obesity. Physiol. Behav. 2005, 86:661-668.
    • (2005) Physiol. Behav. , vol.86 , pp. 661-668
    • Plagemann, A.1
  • 60
    • 0033035278 scopus 로고    scopus 로고
    • Malformations of hypothalamic nuclei in hyperinsulinemic offspring of rats with gestational diabetes
    • Plagemann A., Harder T., Janert U., Rake A., Rittel F., Rohde W., Dorner G. Malformations of hypothalamic nuclei in hyperinsulinemic offspring of rats with gestational diabetes. Dev. Neurosci. 1999, 21:58-67.
    • (1999) Dev. Neurosci. , vol.21 , pp. 58-67
    • Plagemann, A.1    Harder, T.2    Janert, U.3    Rake, A.4    Rittel, F.5    Rohde, W.6    Dorner, G.7
  • 61
    • 0030821719 scopus 로고    scopus 로고
    • Glucose tolerance and insulin secretion in children of mothers with pregestational IDDM or gestational diabetes
    • Plagemann A., Harder T., Kohlhoff R., Rohde W., Dorner G. Glucose tolerance and insulin secretion in children of mothers with pregestational IDDM or gestational diabetes. Diabetologia 1997, 40:1094-1100.
    • (1997) Diabetologia , vol.40 , pp. 1094-1100
    • Plagemann, A.1    Harder, T.2    Kohlhoff, R.3    Rohde, W.4    Dorner, G.5
  • 62
    • 0032724718 scopus 로고    scopus 로고
    • Elevation of hypothalamic neuropeptide Y-neurons in adult offspring of diabetic mother rats
    • Plagemann A., Harder T., Melchior K., Rake A., Rohde W., Dorner G. Elevation of hypothalamic neuropeptide Y-neurons in adult offspring of diabetic mother rats. Neuroreport 1999, 10:3211-3216.
    • (1999) Neuroreport , vol.10 , pp. 3211-3216
    • Plagemann, A.1    Harder, T.2    Melchior, K.3    Rake, A.4    Rohde, W.5    Dorner, G.6
  • 63
    • 0032556676 scopus 로고    scopus 로고
    • Hypothalamic insulin and neuropeptide Y in the offspring of gestational diabetic mother rats
    • Plagemann A., Harder T., Rake A., Melchior K., Rittel F., Rohde W., Dorner G. Hypothalamic insulin and neuropeptide Y in the offspring of gestational diabetic mother rats. Neuroreport 1998, 9:4069-4073.
    • (1998) Neuroreport , vol.9 , pp. 4069-4073
    • Plagemann, A.1    Harder, T.2    Rake, A.3    Melchior, K.4    Rittel, F.5    Rohde, W.6    Dorner, G.7
  • 64
    • 79952117544 scopus 로고    scopus 로고
    • Developmental Programming and Diabetes - the Human Experience and Insight from Animal Models Best Practice and Research
    • Poston L. Developmental Programming and Diabetes - the Human Experience and Insight from Animal Models Best Practice and Research. Best. Pract. Res. Clin. Endocrinol. Metab 2010, 24:541-552.
    • (2010) Best. Pract. Res. Clin. Endocrinol. Metab , vol.24 , pp. 541-552
    • Poston, L.1
  • 67
    • 0036034744 scopus 로고    scopus 로고
    • Dietary fatty acid composition during pregnancy and lactation in the rat programs growth and glucose metabolism in the offspring
    • Siemelink M., Verhoef A., Dormans J.A., Span P.N., Piersma A.H. Dietary fatty acid composition during pregnancy and lactation in the rat programs growth and glucose metabolism in the offspring. Diabetologia 2002, 45:1397-1403.
    • (2002) Diabetologia , vol.45 , pp. 1397-1403
    • Siemelink, M.1    Verhoef, A.2    Dormans, J.A.3    Span, P.N.4    Piersma, A.H.5
  • 68
    • 0029040177 scopus 로고
    • Impaired glucose tolerance in adolescent offspring of diabetic mothers. Relationship to fetal hyperinsulinism
    • Silverman B.L., Metzger B.E., Cho N.H., Loeb C.A. Impaired glucose tolerance in adolescent offspring of diabetic mothers. Relationship to fetal hyperinsulinism. Diabetes Care 1995, 18:611-617.
    • (1995) Diabetes Care , vol.18 , pp. 611-617
    • Silverman, B.L.1    Metzger, B.E.2    Cho, N.H.3    Loeb, C.A.4
  • 70
    • 33644878024 scopus 로고    scopus 로고
    • Maternal hyperinsulinemia predisposes rat fetuses for hyperinsulinemia, and adult-onset obesity and maternal mild food restriction reverses this phenotype
    • Srinivasan M., Aalinkeel R., Song F., Mitrani P., Pandya J.D., Strutt B., Hill D.J., Patel M.S. Maternal hyperinsulinemia predisposes rat fetuses for hyperinsulinemia, and adult-onset obesity and maternal mild food restriction reverses this phenotype. Am. J. Physiol. Endocrinol. Metab. 2006, 290:E129-E134.
    • (2006) Am. J. Physiol. Endocrinol. Metab. , vol.290
    • Srinivasan, M.1    Aalinkeel, R.2    Song, F.3    Mitrani, P.4    Pandya, J.D.5    Strutt, B.6    Hill, D.J.7    Patel, M.S.8
  • 71
    • 33749234763 scopus 로고    scopus 로고
    • Maternal high-fat diet consumption results in fetal malprogramming predisposing to the onset of metabolic syndrome-like phenotype in adulthood
    • E792-9
    • Srinivasan M., Katewa S.D., Palaniyappan A., Pandya J.D., Patel M.S. Maternal high-fat diet consumption results in fetal malprogramming predisposing to the onset of metabolic syndrome-like phenotype in adulthood. Am. J. Physiol. Endocrinol. Metab. 2006, 291. E792-9.
    • (2006) Am. J. Physiol. Endocrinol. Metab. , vol.291
    • Srinivasan, M.1    Katewa, S.D.2    Palaniyappan, A.3    Pandya, J.D.4    Patel, M.S.5
  • 72
    • 34247605492 scopus 로고    scopus 로고
    • Prevalence of nonalcoholic fatty liver disease and its association with cardiovascular disease among type 2 diabetic patients
    • Targher G., Bertolini L., Padovani R., Rodella S., Tessari R., Zenari L., Day C., Arcaro G. Prevalence of nonalcoholic fatty liver disease and its association with cardiovascular disease among type 2 diabetic patients. Diabetes Care 2007, 30:1212-1218.
    • (2007) Diabetes Care , vol.30 , pp. 1212-1218
    • Targher, G.1    Bertolini, L.2    Padovani, R.3    Rodella, S.4    Tessari, R.5    Zenari, L.6    Day, C.7    Arcaro, G.8
  • 76
    • 0029877182 scopus 로고    scopus 로고
    • Familial aggregation of type 2 (non-insulin-dependent) diabetes mellitus in south India; absence of excess maternal transmission
    • Viswanathan M., McCarthy M.I., Snehalatha C., Hitman G.A., Ramachandran A. Familial aggregation of type 2 (non-insulin-dependent) diabetes mellitus in south India; absence of excess maternal transmission. Diabet Med. 1996, 13:232-237.
    • (1996) Diabet Med. , vol.13 , pp. 232-237
    • Viswanathan, M.1    McCarthy, M.I.2    Snehalatha, C.3    Hitman, G.A.4    Ramachandran, A.5
  • 77
    • 0033927322 scopus 로고    scopus 로고
    • Long-term follow-up of infants of mothers with type 1 diabetes: evidence for hereditary and nonhereditary transmission of diabetes and precursors
    • Weiss P.A., Scholz H.S., Haas J., Tamussino K.F., Seissler J., Borkenstein M.H. Long-term follow-up of infants of mothers with type 1 diabetes: evidence for hereditary and nonhereditary transmission of diabetes and precursors. Diabetes Care 2000, 23:905-911.
    • (2000) Diabetes Care , vol.23 , pp. 905-911
    • Weiss, P.A.1    Scholz, H.S.2    Haas, J.3    Tamussino, K.F.4    Seissler, J.5    Borkenstein, M.H.6
  • 78
    • 33645282282 scopus 로고    scopus 로고
    • A low maternal protein diet during pregnancy and lactation has sex- and window of exposure-specific effects on offspring growth and food intake, glucose metabolism and serum leptin in the rat
    • Zambrano E., Bautista C.J., Deas M., Martinezs-Samayoa P.M., Gonzalez-Zamorano M., Ledesma H., Morales J., Larrea F., Nathanielsz P.W. A low maternal protein diet during pregnancy and lactation has sex- and window of exposure-specific effects on offspring growth and food intake, glucose metabolism and serum leptin in the rat. J. Physiol. 2006, 571:221-230.
    • (2006) J. Physiol. , vol.571 , pp. 221-230
    • Zambrano, E.1    Bautista, C.J.2    Deas, M.3    Martinezs-Samayoa, P.M.4    Gonzalez-Zamorano, M.5    Ledesma, H.6    Morales, J.7    Larrea, F.8    Nathanielsz, P.W.9
  • 79
    • 22144440895 scopus 로고    scopus 로고
    • Sex differences in transgenerational alterations of growth and metabolism in progeny (F2) of female offspring (F1) of rats fed a low protein diet during pregnancy and lactation
    • Zambrano E., Martinez-Samayoa P.M., Bautista C.J., Deas M., Guillen L., Rodriguez-Gonzalez G.L., Guzman C., Larrea F., Nathanielsz P.W. Sex differences in transgenerational alterations of growth and metabolism in progeny (F2) of female offspring (F1) of rats fed a low protein diet during pregnancy and lactation. J. Physiol. 2005, 566:225-236.
    • (2005) J. Physiol. , vol.566 , pp. 225-236
    • Zambrano, E.1    Martinez-Samayoa, P.M.2    Bautista, C.J.3    Deas, M.4    Guillen, L.5    Rodriguez-Gonzalez, G.L.6    Guzman, C.7    Larrea, F.8    Nathanielsz, P.W.9
  • 80
    • 75449102371 scopus 로고    scopus 로고
    • Role of PKCzeta translocation in the development of type 2 diabetes in rats following continuous glucose infusion
    • Zhang J.F., Yang J.P., Wang G.H., Xia Z., Duan S.Z., Wu Y. Role of PKCzeta translocation in the development of type 2 diabetes in rats following continuous glucose infusion. Diabetes Metab. Res. Rev. 2010, 26:59-70.
    • (2010) Diabetes Metab. Res. Rev. , vol.26 , pp. 59-70
    • Zhang, J.F.1    Yang, J.P.2    Wang, G.H.3    Xia, Z.4    Duan, S.Z.5    Wu, Y.6


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