Effect of switching antithrombin agents for primary angioplasty in acute myocardial infarction: The HORIZONS-SWITCH analysis

Journal of the American College of Cardiology

Volumn 57, Issue 23, 2011, Pages 2309-2316

  Dangas, George D ^a,c   Mehran, Roxana ^a,c   Nikolsky, Eugenia ^c   Claessen, Bimmer E ^c   Lansky, Alexandra J ^c,d   Brodie, Bruce R ^e   Witzenbichler, Bernhard ^f   Guagliumi, Giulio ^g   Peruga, Jan Z ⁱ   Dudek, Dariusz ^j   McKel, Martin ^f   Caixeta, Adriano ^c   Parise, Helen ^c   White, Harvey ^h   Stone, Gregg W ^b,c  

^a MOUNT SINAI MEDICAL CENTER   (United States)

^b NewYork Presbyterian Hospital   (United States)

^c CARDIOVASCULAR RESEARCH FOUNDATION   (United States)

^d YALE UNIVERSITY MEDICAL CENTER   (United States)

^e MOSES H CONE MEMORIAL HOSPITAL   (United States)

^f CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^g OSPEDALI RIUNITI   (Italy)

^h AUCKLAND CITY HOSPITAL   (New Zealand)

ⁱ Medical University of Lodz Bieganski Hospital   (Poland)

^j JAGIELLONIAN UNIVERSITY   (Poland)

more..

Author keywords

angioplasty; myocardial infarction; stent; stent thrombosis

Indexed keywords

ABCIXIMAB; CLOPIDOGREL; EPTIFIBATIDE; HEPARIN; HIRULOG; PACLITAXEL; TIROFIBAN;

ACUTE HEART INFARCTION; ADULT; AGED; ARTICLE; BLEEDING; CONTROLLED STUDY; CORONARY STENT; DRUG DOSE COMPARISON; DRUG SUBSTITUTION; DRUG WITHDRAWAL; FEMALE; HEART REINFARCTION; HUMAN; LOADING DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTICENTER STUDY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; STENT THROMBOSIS; SURVIVAL RATE; SURVIVAL TIME; TRANSLUMINAL CORONARY ANGIOPLASTY;

AGED; ANGIOPLASTY, BALLOON, CORONARY; ANTITHROMBINS; FEMALE; HEPARIN; HIRUDINS; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; PEPTIDE FRAGMENTS; RECOMBINANT PROTEINS; TREATMENT OUTCOME;

EID: 79958010746     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2011.01.038     Document Type: Article

References (16)

1. F.G. Kushner, M. Hand, and S.C. Smith Jr. 2009 focused updates: ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction (updating the 2004 guideline and 2007 focused update) and ACC/AHA/SCAI guidelines on percutaneous coronary intervention (updating the 2005 guideline and 2007 focused update): a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines J Am Coll Cardiol 54 2009 2205 2241
2. F. Van de Werf, J. Bax, and A. Betriu Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation: the Task Force on the Management of ST-Segment Elevation Acute Myocardial Infarction of the European Society of Cardiology Eur Heart J 29 2008 2909 2945
3. G.W. Stone, B. Witzenbichler, and G. Guagliumi Bivalirudin during primary PCI in acute myocardial infarction N Engl J Med 358 2008 2218 2230 (Pubitemid 351724451)
4. R. Mehran, A.J. Lansky, and B. Witzenbichler Bivalirudin in patients undergoing primary angioplasty for acute myocardial infarction (HORIZONS-AMI): 1-year results of a randomised controlled trial Lancet 374 2009 1149 1159
5. M. Cohen, K.W. Mahaffey, and K. Pieper A subgroup analysis of the impact of prerandomization antithrombin therapy on outcomes in the SYNERGY trial: enoxaparin versus unfractionated heparin in non-ST-segment elevation acute coronary syndromes J Am Coll Cardiol 48 2006 1346 1354 (Pubitemid 44436804)
6. H.D. White, D.P. Chew, and J.W. Hoekstra Safety and efficacy of switching from either unfractionated heparin or enoxaparin to bivalirudin in patients with non-ST-segment elevation acute coronary syndromes managed with an invasive strategy: results from the ACUITY (Acute Catheterization and Urgent Intervention Triage strategY) trial J Am Coll Cardiol 51 2008 1734 1741 (Pubitemid 351621989)
7. R. Mehran, B. Brodie, and D.A. Cox The Harmonizing Outcomes with RevasculariZatiON and Stents in Acute Myocardial Infarction (HORIZONS-AMI) trial: study design and rationale Am Heart J 156 2008 44 56 (Pubitemid 351862292)
8. G.W. Stone, A.J. Lansky, and S.J. Pocock Paclitaxel-eluting stents versus bare-metal stents in acute myocardial infarction N Engl J Med 360 2009 1946 1959
9. A.K. Rao, C. Pratt, and A. Berke Thrombolysis in Myocardial Infarction (TIMI) Trialphase I: hemorrhagic manifestations and changes in plasma fibrinogen and the fibrinolytic system in patients treated with recombinant tissue plasminogen activator and streptokinase J Am Coll Cardiol 11 1988 1 11 (Pubitemid 18029027)
10. D.E. Cutlip, S. Windecker, and R. Mehran Clinical end points in coronary stent trials: a case for standardized definitions Circulation 115 2007 2344 2351 (Pubitemid 46685903)
11. R. Waksman, R.M. Wolfram, and R.L. Torguson Switching from Enoxaparin to Bivalirudin in Patients with Acute Coronary Syndromes without ST-segment Elevation who Undergo Percutaneous Coronary Intervention Results from SWITCHa multicenter clinical trial J Invasive Cardiol 18 2006 370 375 (Pubitemid 44178973)
12. W.B. Hillegass, B.C. Brott, and G.D. Chapman Relationship between activated clotting time during percutaneous intervention and subsequent bleeding complications Am Heart J 144 2002 501 507
13. G.D. Dangas, A. Caixeta, and R. Mehran Frequency and predictors of stent thrombosis after percutaneous coronary intervention in acute myocardial infarction Circulation 123 2011 1745 1756
14. G. Dangas, E.D. Aymong, and R. Mehran Predictors of and outcomes of early thrombosis following balloon angioplasty versus primary stenting in acute myocardial infarction and usefulness of abciximab (the CADILLAC trial) Am J Cardiol 94 2004 983 988 (Pubitemid 39336427)
15. G. De Luca, H. Suryapranata, and G.W. Stone Abciximab as adjunctive therapy to reperfusion in acute ST-segment elevation myocardial infarction: a meta-analysis of randomized trials JAMA 293 2005 1759 1765
16. K.A. Fox, P.G. Steg, and K.A. Eagle Decline in rates of death and heart failure in acute coronary syndromes, 19992006 JAMA 297 2007 1892 1900 (Pubitemid 46707843)