The anti-atherogenic aspect of metformin treatment in insulin resistant women with the polycystic ovary syndrome: Role of the newly established pro-inflammatory adipokine Acute-phase Serum Amyloid A; evidence of an adipose tissue-monocyte axis

Atherosclerosis

Volumn 216, Issue 2, 2011, Pages 402-408

  Tan, Bee K ^a,b   Adya, Raghu ^a   Shan, Xiaoye ^a   Aghilla, Mohamed ^a   Lehnert, Hendrik ^a,c   Keay, Stephen D ^a   Randeva, Harpal S ^a  

^a UNIVERSITY OF WARWICK   (United Kingdom)

^b ADDENBROOKE S HOSPITAL   (United Kingdom)

^c UNIVERSITY OF LÜBECK   (Germany)

Author keywords

Adipokine; Atherosclerosis; Inflammation; Insulin resistance; Metformin; PCOS; Serum amyloid A

Indexed keywords

ACUTE PHASE SERUM AMYLOID A; ADIPOCYTOKINE; GLUCOSE; MESSENGER RNA; METFORMIN; SERUM AMYLOID A; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ADULT; ARTERIAL WALL THICKNESS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DOSE INCREASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN CELL; INSULIN RESISTANCE; MONOCYTE; OVARY POLYCYSTIC DISEASE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN SECRETION; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ADIPOKINES; ADIPOSE TISSUE; ADULT; ANIMALS; ATHEROSCLEROSIS; CASE-CONTROL STUDIES; FEMALE; HUMANS; INFLAMMATION; INSULIN RESISTANCE; MACROPHAGES; METFORMIN; MONOCYTES; POLYCYSTIC OVARY SYNDROME; SERUM AMYLOID A PROTEIN;

EID: 79957999071     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2010.08.069     Document Type: Article

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