Brain injury after intracerebral hemorrhage in spontaneously hypertensive rats: Laboratory investigation

Journal of Neurosurgery

Volumn 114, Issue 6, 2011, Pages 1805-1811

  Wu, Gang ^a   Bao, Xuhui ^a   Xi, Guohua ^a   Keep, Richard F ^a   Thompson, B Gregory ^a   Hua, Ya ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Brain edema; Cerebral hemorrhage; Ferritin; Hypertension; Microglia; Neuronal death

Indexed keywords

COLLAGENASE; FERRITIN; HEMOGLOBIN; WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BASAL GANGLION; BLOOD AUTOTRANSFUSION; BRAIN EDEMA; BRAIN FUNCTION; BRAIN HEMATOMA; BRAIN HEMORRHAGE; BRAIN INJURY; BRAIN WATER; CELL ACTIVATION; CEREBELLUM; CONTROLLED STUDY; HEMOGLOBIN BLOOD LEVEL; HYPERTENSION; IMMUNOREACTIVITY; MALE; MICROGLIA; NERVE CELL; NERVE CELL NECROSIS; NEUROLOGIC DISEASE; NEUROLOGIC EXAMINATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SYSTOLIC BLOOD PRESSURE; WATER CONTENT;

ANIMALS; BLOOD PRESSURE; BLOTTING, WESTERN; BRAIN; BRAIN EDEMA; BRAIN INJURIES; CEREBRAL HEMORRHAGE; DISEASE MODELS, ANIMAL; FERRITINS; IMMUNOHISTOCHEMISTRY; MALE; RATS; RATS, INBRED SHR; RATS, INBRED WKY;

EID: 79957994303     PISSN: 00223085     EISSN: 19330693     Source Type: Journal    
DOI: 10.3171/2011.1.JNS101530     Document Type: Article

References (34)

1. Al-Sarraf H, Philip L: Effect of hypertension on the integrity of blood brain and blood CSF barriers, cerebral blood flow and CSF secretion in the rat. Brain Res 975:179-188, 2003 (Pubitemid 36588565)
2. Amagasa H, Okazaki M, Iwai S, Kumai T, Kobayashi S, Oguchi K: Enhancement of the coagulation system in spontaneously hypertensive and hyperlipidemic rats. J Atheroscler Thromb 12:191-198, 2005
3. Anderson CS, Huang Y, Arima H, Heeley E, Skulina C, Parsons MW, et al: Effects of early intensive blood pressure-lowering treatment on the growth of hematoma and perihematomal edema in acute intracerebral hemorrhage: the Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT). Stroke 41:307-312, 2010
4. Anderson CS, Huang Y, Wang JG, Arima H, Neal B, Peng B, et al: Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT): a randomised pilot trial. Lancet Neurol 7:391-399, 2008
5. Broderick JP, Diringer MN, Hill MD, Brun NC, Mayer SA, Steiner T, et al: Determinants of intracerebral hemorrhage growth: an exploratory analysis. Stroke 38:1072-1075, 2007 (Pubitemid 46568477)
6. Gong C, Hoff JT, Keep RF: Acute inflammatory reaction following experimental intracerebral hemorrhage in rat. Brain Res 871:57-65, 2000 (Pubitemid 30406868)
7. Gong Y, Hua Y, Keep RF, Hoff JT, Xi G: Intracerebral hemorrhage: effects of aging on brain edema and neurological deficits. Stroke 35:2571-2575, 2004 (Pubitemid 39458419)
8. González-Darder JM, Durán-Cabral J: Experimental intracerebral haemorrhage in normotensive and spontaneously hypertensive rats. Acta Neurochir (Wien) 107:102-107, 1990
9. Gu Y, Hua Y, Keep RF, Morgenstern LB, Xi G: Deferoxamine reduces intracerebral hematoma-induced iron accumulation and neuronal death in piglets. Stroke 40:2241-2243, 2009
10. Henning EC, Latour LL, Hallenbeck JM, Warach S: Reperfusion-associated hemorrhagic transformation in SHR rats: evidence of symptomatic parenchymal hematoma. Stroke 39: 3405-3410, 2008
11. Hua Y, Keep RF, Hoff JT, Xi G: Brain injury after intracerebral hemorrhage: the role of thrombin and iron. Stroke 38 (2 Suppl):759-762, 2007 (Pubitemid 46184254)
12. Hua Y, Schallert T, Keep RF, Wu J, Hoff JT, Xi G: Behavioral tests after intracerebral hemorrhage in the rat. Stroke 33:2478-2484, 2002
13. Jenkins A, Maxwell WL, Graham DI: Experimental intracerebral haematoma in the rat: sequential light microscopical changes. Neuropathol Appl Neurobiol 15:477-486, 1989 (Pubitemid 19256647)
14. Kitaoka T, Hua Y, Xi G, Hoff JT, Keep RF: Delayed argatroban treatment reduces edema in a rat model of intracerebral hemorrhage. Stroke 33:3012-3018, 2002 (Pubitemid 35462880)
15. Lecrux C, Nicole O, Chazalviel L, Catone C, Chuquet J, Mac Kenzie ET, et al: Spontaneously hypertensive rats are highly vulnerable to AMPA-induced brain lesions. Stroke 38:3007-3015, 2007 (Pubitemid 350035697)
16. Mehdiratta M, Kumar S, Hackney D, Schlaug G, Selim M: Association between serum ferritin level and perihematoma edema volume in patients with spontaneous intracerebral hem orrhage. Stroke 39:1165-1170, 2008 (Pubitemid 351440686)
17. Mendelow AD, Gregson BA, Fernandes HM, Murray GD, Teasdale GM, Hope DT, et al: Early surgery versus initial conservative treatment in patients with spontaneous supratentorial intracerebral haematomas in the International Surgical Trial in Intracerebral Haemorrhage (STICH): a randomised trial. Lancet 365:387-397, 2005 (Pubitemid 40179225)
18. Miller LL, Miller SC, Torti SV, Tsuji Y, Torti FM: Iron-independent induction of ferritin H chain by tumor necrosis factor. Proc Natl Acad Sci U S A 88:4946-4950, 1991 (Pubitemid 21914660)
19. Munakata M, Komiyama Y, Masuda M, Kagawa H, Nomura S, Fukuhara S, et al: Whole blood prothrombin time using diluted tissue factor is shortened in spontaneous hypertensive rats. Semin Thromb Hemost 26:97-100, 2000 (Pubitemid 30238025)
20. Okauchi M, Hua Y, Keep RF, Morgenstern LB, Schallert T, Xi G: Deferoxamine treatment for intracerebral hemorrhage in aged rats: therapeutic time window and optimal duration. Stroke 41:375-382, 2010
21. Pérez de la Ossa N, Sobrino T, Silva Y, Blanco M, Millán M, Gomis M, et al: Iron-related brain damage in patients with intracerebral hemorrhage. Stroke 41:810-813, 2010
22. Qin Z, Karabiyikoglu M, Hua Y, Silbergleit R, He Y, Keep RF, et al: Hyperbaric oxygen-induced attenuation of hemorrhagic transformation after experimental focal transient cerebral ischemia. Stroke 38:1362-1367, 2007 (Pubitemid 351664269)
23. Qureshi AI, Ezzeddine MA, Nasar A, Suri MF, Kirmani JF, Hussein HM, et al: Prevalence of elevated blood pressure in 563,704 adult patients with stroke presenting to the ED in the United States. Am J Emerg Med 25:32-38, 2007 (Pubitemid 44869006)
24. Qureshi AI, Palesch YY, Martin R, Novitzke J, Cruz-Flores S, Ehtisham A, et al: Effect of systolic blood pressure reduction on hematoma expansion, perihematomal edema, and 3-month outcome among patients with intracerebral hemorrhage: results from the antihypertensive treatment of acute cerebral hemorrhage study. Arch Neurol 67:570-576, 2010
25. Ropper AH: Lateral displacement of the brain and level of consciousness in patients with an acute hemispheral mass. N Engl J Med 314:953-958, 1986
26. Varughese GI, Lip GY: Is hypertension a prothrombotic state? Curr Hypertens Rep 7:168-173, 2005 (Pubitemid 40894921)
27. Veerasingham SJ, Yamazato M, Berecek KH, Wyss JM, Raizada MK: Increased PI3-kinase in presympathetic brain areas of the spontaneously hypertensive rat. Circ Res 96:277-279, 2005 (Pubitemid 40279901)
28. Wang J, Rogove AD, Tsirka AE, Tsirka SE: Protective role of tuftsin fragment 1-3 in an animal model of intracerebral hemorrhage. Ann Neurol 54:655-664, 2003 (Pubitemid 37346072)
29. Wirth KJ, Linz W, Wiemer G, Schölkens BA: Differences in acetylcholine- and bradykinin-induced vasorelaxation of the mesenteric vascular bed in spontaneously hypertensive rats of different ages. Naunyn Schmiedebergs Arch Pharmacol 354:38-43, 1996 (Pubitemid 26228457)
30. Wu J, Hua Y, Keep RF, Nakamura T, Hoff JT, Xi G: Iron and iron-handling proteins in the brain after intracerebral hemorrhage. Stroke 34:2964-2969, 2003 (Pubitemid 37517778)
31. Wu J, Yang S, Xi G, Fu G, Keep RF, Hua Y: Minocycline reduces intracerebral hemorrhage-induced brain injury. Neurol Res 31:183-188, 2009
32. Xi G, Keep RF, Hoff JT: Mechanisms of brain injury after intracerebral haemorrhage. Lancet Neurol 5:53-63, 2006 (Pubitemid 41790696)
33. Xi G, Keep RF, Hua Y, Xiang JM, Hoff JT: Attenuation of thrombin-induced brain edema by cerebral thrombin preconditioning. Stroke 30:1247-1255, 1999 (Pubitemid 29259182)
34. Yang H, Raizada MK: MAP kinase-independent signaling in angiotensin II regulation of neuromodulation in SHR neurons. Hypertension 32:473-481, 1998 (Pubitemid 28429136)