Nickel-catalyzed Kumada cross-coupling reactions of tertiary alkylmagnesium halides and aryl bromides/triflates

Journal of the American Chemical Society

Volumn 133, Issue 22, 2011, Pages 8478-8481

  Joshi Pangu, Amruta ^a   Wang, Chao Yuan ^a   Biscoe, Mark R ^a  

^a CITY COLLEGE OF NEW YORK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARYL BROMIDES; ARYL TRIFLATES; CROSS-COUPLINGS; ELECTROPHILES; KUMADA CROSS-COUPLING; VINYL BROMIDES; VINYL CHLORIDES;

BROMINE COMPOUNDS; CHLORINE COMPOUNDS;

CATALYSIS;

4 BROMOANISOLE; ALKYLMAGNESIUM HALIDE; ANISOLE DERIVATIVE; ELECTROPHILE; GRIGNARD REAGENT; HALIDE; NICKEL; NUCLEOPHILE; ORGANOMETALLIC COMPOUND; TRIFLUOROMETHANESULFONIC ACID; UNCLASSIFIED DRUG; VINYL CHLORIDE;

ARTICLE; BIOTRANSFORMATION; CATALYSIS; CHEMICAL ANALYSIS; CROSS COUPLING REACTION; ELECTROPHILICITY; HYDRATION; ISOMERIZATION; NUCLEOPHILICITY; STOICHIOMETRY;

EID: 79957979491     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja202769t     Document Type: Article

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31. 6 with a mortar and pestle and heating the powder under high vacuum in an oil bath at 100 °C for 20 min, then at 120 °C for an additional 5-10 min (see Supporting Information for more details). The powder was rapidly stirred to ensure homogeneous heating. The extent of dehydration can be readily determined by the mass change before/after heating under vacuum.
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