The oxidation induced by antimyeloperoxidase antibodies triggers fibrosis in microscopic polyangiitis

European Respiratory Journal

Volumn 37, Issue 6, 2011, Pages 1503-1513

  Guilpain, P ^a,c   Chereau C ^a   Goulvestre, C ^a   Servettaz, A ^a   Montani, D ^d   Tamas, N ^b   Pagnoux, C ^b,c   Hachulla, E ^e   Weill, B ^a   Guillevin, L ^b,c   Mouthon, L ^b,c   Batteux, F ^a  

^a Hôpital Cochin ^*  (France)

^b IFR Alfred Jost   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d UNIVERSITÉ PARIS SACLAY   (France)

^e LILLE UNIVERSITY HOSPITAL   (France)

Author keywords

Anti neutrophil cytoplasm antibodies; Fibrosis; Hypochlorous acid; Myeloperoxidase; Vasculitis

Indexed keywords

ADVANCED OXIDATION PROTEIN PRODUCT; AZATHIOPRINE; CYCLOPHOSPHAMIDE; ENZYME ANTIBODY; HYPOCHLOROUS ACID; METHOTREXATE; MYELOPEROXIDASE; MYELOPEROXIDASE ANTIBODY; PREDNISONE; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FIBROBLAST; HUMAN; LOW DRUG DOSE; LUNG FIBROSIS; MALE; MICROSCOPIC POLYANGIITIS; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL;

EID: 79957974029     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00148409     Document Type: Article

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