Pure red cell aplasia induced only by intravenous administration of recombinant human erythropoietin

Acta Haematologica

Volumn 126, Issue 2, 2011, Pages 114-118

  Shimizu, Hiroaki ^a,b   Saitoh, Takayuki ^c   Ota, Fumie ^a   Jimbo, Takahiro ^a   Tsukada, Yoshito ^a   Murakami, Hirokazu ^d   Nojima, Yoshihisa ^c  

^a Fujioka General Hospital   (Japan)

^b SAISEIKAI MAEBASHI HOSPITAL   (Japan)

^c GUNMA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d GUNMA UNIVERSITY   (Japan)

Author keywords

Antibody; Pure red cell aplasia; Recombinant human erythropoietin

Indexed keywords

CYCLOSPORIN; ERYTHROPOIETIN ANTIBODY; HEMOGLOBIN; INSULIN; NOVEL ERYTHROPOIESIS STIMULATING PROTEIN; RECOMBINANT ERYTHROPOIETIN;

AGED; ANTIBODY TITER; ARTICLE; BLOOD TRANSFUSION; BONE MARROW EXAMINATION; CASE REPORT; CHRONIC KIDNEY FAILURE; DIABETIC NEPHROPATHY; DRUG DOSE ESCALATION; DRUG SUBSTITUTION; DRUG WITHDRAWAL; ERYTHROPOIESIS; HEMODIALYSIS; HEMOGLOBIN BLOOD LEVEL; HUMAN; MALE; NORMOCHROMIC NORMOCYTIC ANEMIA; PRIORITY JOURNAL; PURE RED CELL ANEMIA; RADIOIMMUNOASSAY; RETICULOCYTE COUNT;

AGED; AUTOANTIBODIES; DIABETIC NEPHROPATHIES; ERYTHROPOIETIN; ERYTHROPOIETIN, RECOMBINANT; HUMANS; INJECTIONS, INTRAVENOUS; KIDNEY FAILURE, CHRONIC; MALE; RED-CELL APLASIA, PURE;

EID: 79957962714     PISSN: 00015792     EISSN: 14219662     Source Type: Journal    
DOI: 10.1159/000328041     Document Type: Article

References (11)

1. Peces R, de la Torre M, Alcázar R, Urra JM: Antibodies against recombinant human erythropoietin in a patient with erythropoietin- resistant anemia. N Engl J Med 1996; 335: 523-524. (Pubitemid 26269960)
2. Prabhakar SS, Muhlfelder T: Antibodies to recombinant human erythropoietin causing pure red cell aplasia. Clin Nephrol 1997; 47: 331-335. (Pubitemid 27230631)
3. Casadevall N, Nataf J, Viron B, Kolta A, Kiladjian JJ, Martin-Dupont P, Michaud P, Papo T, Ugo V, Teyssandier I, Varet B, Mayeux P: Pure red-cell aplasia and antierythropoietin antibodies in patients treated with recombinant erythropoietin. N Engl J Med 2002; 346: 469-475. (Pubitemid 34441737)
4. Bennett CL, Luminari S, Nissenson AR, Tallman MS, Klinge SA, McWilliams N, McKoy JM, Kim B, Lyons EA, Trifilio SM, Raisch DW, Evens AM, Kuzel TM, Schumock GT, Belknap SM, Locatelli F, Rossert J, Casadevall N: Pure red-cell aplasia and epoetin therapy. N Engl J Med 2004; 351: 1403-1408. (Pubitemid 39288166)
5. Swanson SJ, Ferbas J, Mayeux P, Casadevall N: Evaluation of methods to detect and characterize antibodies against recombinant human erythropoietin. Nephron Clin Pract 2004; 96:c88-c95. (Pubitemid 38453092)
6. Locatelli F, Aljama P, Barany P, Canaud B, Carrera F, Eckardt KU, Macdougall IC, Macleod A, Hörl WH, Wiecek A, Cameron S: Erythropoiesis-stimulating agents and antibody- mediated pure red-cell aplasia: Here are we now and where do we go from here? Nephrol Dial Transplant 2004; 19: 288-293. (Pubitemid 38195972)
7. Hynes DM, Stroupe KT, Greer JW, Reda DJ, Frankenfield DL, Kaufman JS, Henderson WG, Owen WF, Rocco MV, Wish JB, Kang J, Feussner JR: Potential cost savings of erythropoietin administration in end-stage renal disease. Am J Med 2002; 112: 169-175.
8. Porter S: Human immune response to recombinant human proteins. J Pharm Sci 2001; 90: 1-11. (Pubitemid 32050471)
9. McKoy JM, Stonecash RE, Cournoyer D, Rossert J, Nissenson AR, Raisch DW, Casadevall N, Bennett CL: Epoetin-associated pure red cell aplasia: Past, present, and future considerations. Transfusion 2008; 48: 1754-1762.
10. Thorpe R, Swanson SJ: Assays for detecting and diagnosing antibody-mediated pure red cell aplasia (PRCA): An assessment of available procedures. Nephrol Dial Transplant 2005; 20: 16-22.
11. Bennett CL, Cournoyer D, Carson KR, Rossert J, Luminari S, Evens AM, Locatelli F, Belknap SM, McKoy JM, Lyons EA, Kim B, Sharma R, Costello S, Toffelmire EB, Wells GA, Messner HA, Yarnold PR, Trifilio SM, Raisch DW, Kuzel TM, Nissenson A, Lim LC, Tallman MS, Casadevall N: Long-term outcome of individuals with pure red cell aplasia and antierythropoietin antibodies in patients treated with recombinant epoetin: A follow-up report from the Research on Adverse Drug Events and Reports (RADAR) Project. Blood 2005; 106: 3343-3347. (Pubitemid 41609162)