A microfluidic multichannel resistive pulse sensor using frequency division multiplexing for high throughput counting of micro particles

Journal of Micromechanics and Microengineering

Volumn 21, Issue 6, 2011, Pages

  Jagtiani, Ashish V ^a   Carletta, Joan ^a   Zhe, Jiang ^a  

^a The University of Akron   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COULTER COUNTERS; EXTERNAL DETECTION; HIGH THROUGHPUT; MEASURED SIGNALS; MICRO PARTICLES; MICRO-SCALE PARTICLES; MICROFLUIDIC CHANNEL; MODULATION METHODS; MULTI-CHANNEL; MULTIPLEXED DETECTION; ON CHIPS; PARALLEL CHANNEL; POLARIZATION EFFECT; POLYSTYRENE PARTICLE; RESISTIVE PULSE SENSORS; SINGLE-CHANNEL; TESTING RESULTS;

FREQUENCY ALLOCATION; FREQUENCY DIVISION MULTIPLEXING; MICROELECTRODES; MICROFLUIDICS; PARTICLE SIZE; POLYSTYRENES; SENSORS; SIGNAL DETECTION;

THROUGHPUT;

EID: 79957955719     PISSN: 09601317     EISSN: 13616439     Source Type: Journal    
DOI: 10.1088/0960-1317/21/6/065004     Document Type: Article

References (40)

1. DeBlois R W and Bean C P 1970 Counting and sizing of submicron particles by the resistive pulse technique Rev. Sci. Instrum. 41 909-15
2. Henriquez R R, Ito T, Sun L and Crooks R M 2004 The resurgence of Coulter counting for analyzing nanoscale objects Analyst 129 478-82 (Pubitemid 38813510)
3. Zimmermann U, Pilwat G and Riemann F 1974 Dielectric breakdown of cell membranes Biophys. J. 14 881-99
4. Saleh O A and Sohn L L 2001 Quantitative sensing of nanoscale colloids using a microchip Coulter counter Rev. Sci. Instrum. 72 4449-51
5. Heng J B, Ho C, Kim T, Timp R, Aksimentiev A, Grinkova Y V, Sligar S, Schulten K and Timp G 2004 Sizing DNA using a nanometer-diameter pore Biophys. J. 87 2905-11
6. Kasianiwicz J J, Brandin E, Branton D and Dreamer D W 1996 Characterization of individual polynucleotide molecules using a membrane channel Proc. Natl Acad. Sci. 93 13770-3 (Pubitemid 26424195)
7. DeBlois R W and Wesley R K 1977 Sizes and concentrations of several type C oncornaviruses and bacteriophage T2 by the resistive-pulse technique J. Virol. 23 227-33 (Pubitemid 8148483)
8. Zheng Z, Zhe J, Chandra S and Hu J 2005 An electronic pollen detection method using Coulter counting principle Atmos. Environ. 39 5446-53 (Pubitemid 41254129)
9. Jagtiani A, Zhe J, Hu J and Carletta J 2006 Detection and counting of micro-scale particles and pollen using a multi-aperture Coulter counter Meas. Sci. Technol. 17 1706-14 (Pubitemid 43958847)
10. Saleh O A and Sohn L L 2003 Direct detection of antibody-antigen binding using an on-chip artificial pore Proc. Natl Acad. Sci. 100 820-4 (Pubitemid 36183914)
11. Gawad S, Schild L and Renaud Ph 2001 Micromachined impedance spectroscopy flow cytometer for cell analysis and particle sizing Lab Chip 1 76-82
12. Wood D K, Oh S-H and Lee S-H 2005 High-bandwidth radio frequency Coulter counter Appl. Phys. Lett. 87 184106
13. Wood D K, Requa M V and Cleland A N 2007 Micro fabricated high throughput electronic particle detector Rev. Sci. Instrum. 78 104301
14. Wu X, Kang Y, Wang Y-N, Xu D, Li D and Li D 2008 Microfluidic differential resistive pulse sensors Electrophoresis 29 2754-9 (Pubitemid 352006109)
15. Wang Y-N, Kang Y, Xu D, Chon C H, Barnett L, Kalams S A, Li D and Li D 2008 On-chip counting the number and the percentage of CD4+ T lymphocytes Lab Chip 8 309-15 (Pubitemid 351191411)
16. Sridhar M, Xu D, Kang Y, Hmelo A B, Feldman L C, Li D and Li D 2008 Experimental characterization of a metal-oxide-semiconductor field effect transistor-based Coulter counter J. Appl. Phys. 103 104701
17. Xu D, Kang Y, Sridhar M, Hmelo A B, Feldman L C, Li D and Li D 2007 Wide-spectrum, ultrasensitive fluidic sensors with amplification from both fluidic circuits and metal oxide semiconductor field effect transistors Appl. Phys. Lett. 91 013901 (Pubitemid 350092142)
18. Wu X, Chon C H, Wang Y-N, Kang Y and Li D 2008 Simultaneous particle counting and detection on a chip Lab Chip 8 1943-9
19. Jagtiani A, Sawant R and Zhe J 2006 A label-free high throughput resistive-pulse sensor for simultaneous differentiation and measurement of multiple particle-laden analytes J. Micromech. Microeng. 16 1530-9 (Pubitemid 44102300)
20. Coulter W H and Hogg W R 1969 Particle analyzing apparatus and method utilizing multiple apertures US Patent 3444463
21. Carbonaro A and Sohn L L 2005 A resistive-pulse sensor chip for multianalyte immunoassays Lab Chip 5 1155-60 (Pubitemid 41453007)
22. Zhe J, Jagtiani A, Dutta P, Hu J and Carletta J 2006 A micromachined high throughput resistive-pulse sensor for bioparticle detection and counting J. Micromech. Microeng. 17 304-13
23. Jagtiani A and Zhe J 2010 High throughput microfluidic electrical impedance flow cytometry for assay of micro particles Micro Nanosyst. 2 1-4
24. Duffy D C, McDonald J C, Schueller O J A and Whitesides G M 1998 Rapid prototyping of microfluidic systems in poly(dimethylsiloxane) Anal. Chem. 70 4974-84
25. Zou Z, Kai J, Rust M J, Han J and Ahn C H 2007 Functionalized nano interdigitated electrodes arrays on polymer with integrated microfluidics for direct bio-affinity sensing using impedimetric measurement Sensors Actuators A 136 518-26 (Pubitemid 46678731)
26. Kline S J 1985 The purpose of uncertainty analysis ASME J. Fluid Eng. 107 153-60
27. Moffat R J 1988 Describing the uncertainties in experimental results Exp. Therm. Fluid Sci. 1 3-17
28. Steele W G, Ferguson R A, Taylor R P and Coleman H W 1997 Computer assisted uncertainty analysis Comput. Appl. Eng. Educ. 5 169-79
29. Coleman H W and Steele W G 1995 Engineering application of experimental uncertainty analysis AIAA J. 33 1888-96
30. Berge L I, Jossang T and Feder J 1990 Off-axis response for particle passing through long apertures in Coulter type counters Meas. Sci. Technol. 1 471-4 (Pubitemid 20696684)
31. Ito T, Sun L, Henriquez R R and Crooks R M 2004 A carbon nanotube-based Coulter nanoparticle counter Acc. Chem. Res. 37 937-45 (Pubitemid 40066146)
32. Carbonaro A, Huang H, Godley L A and Sohn L L 2008 Cell characterization using protein-functionalized pore Lab Chip 9 1478-85
33. Golibersuch D C 1973 Observation of aspherical particle rotation in Poiseuille flow via the resistance pulse technique: I. Application to human erythrocytes Biophys. J. 13 265-80
34. Hurley J 1970 Sizing particles with a Coulter counter Biophys. J. 10 74-9
35. Golibersuch D C 1973 Observation of aspherical particle rotation in Poiseuille flow via the resistance pulse technique: II. Application to fused sphere dumbbells J. Appl. Phys. 44 2580-4
36. Waterman C S, Atkinson E E Jr, Wilkins B Jr, Fischer C L and Kimzey S L 1975 Improved measurement of erythrocyte volume distribution by aperture-counter signal analysis Clin. Chem. 21 1201-11
37. Saleh O A 2003 A novel resistive pulse sensor for biological measurement PhD Dissertation Princeton University, Department of Physics
38. Hua S Z and Pennell T 2008 A microfluidic chip for real-time studies of volume of single cells Lab Chip 9 251-6
39. Fuller C K, Hamilton J, Ackler H, Krulevitch P, Boser B, Eldredge A, Becker F, Yang J and Gascoyne P 2000 Microfabricated multi-frequency particle impedance characterization system Proc. Micro Total Analysis Systems 2000 (The Netherlands, 14-18 May) pp 265-8
40. Li Z 2005 A low-phase-noise and low-power multiband CMOS voltage-controlled oscillator IEEE J. Solid-State Circuits 40 1296