Rescuing hepatocytes from iron-catalyzed oxidative stress using vitamins B1 and B6

Toxicology in Vitro

Volumn 25, Issue 5, 2011, Pages 1114-1122

  Mehta, Rhea ^a   Dedina, Liana ^b   O'Brien, Peter J ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Cytotoxicity; Free radical; Hepatocytes; Iron; Lipid peroxidation; Reactive oxygen species

Indexed keywords

AMINOGUANIDINE; ANTIOXIDANT; BUTYLATED HYDROXYANISOLE; FREE RADICAL; IRON; PENICILLAMINE; PYRIDOXAMINE; PYRIDOXINE; QUERCETIN; REACTIVE OXYGEN METABOLITE; THIAMINE;

ANIMAL CELL; ARTICLE; CELL MEDIATED CYTOTOXICITY; CELL PROTECTION; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; DNA DAMAGE; DRUG EFFICACY; DRUG MECHANISM; IN VITRO STUDY; LIPID PEROXIDATION; LIVER TOXICITY; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PROTEIN CARBONYLATION; PROTEIN OXIDATION; RAT;

ANIMALS; ANTIOXIDANTS; BUTYLATED HYDROXYANISOLE; CELL SURVIVAL; CELLS, CULTURED; COMET ASSAY; CYTOPROTECTION; DEOXYRIBOSE; DNA DAMAGE; GUANIDINES; HEPATOCYTES; IRON; LIPID PEROXIDATION; MALE; MITOCHONDRIA; OXIDATIVE STRESS; PHENANTHROLINES; PROTEIN CARBONYLATION; PYRIDOXAMINE; QUERCETIN; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; THIAMINE; VITAMIN B 6; VITAMIN B COMPLEX;

EID: 79957951936     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2011.03.015     Document Type: Article

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