An evaluation of the impact of a single-dose intravenous immunoglobulin regimen in the treatment of clostridium difficile infections

Infection Control and Hospital Epidemiology

Volumn 32, Issue 6, 2011, Pages 631-633

  Aldeyab, Mamoon A ^a   McElnay, James C ^a   Scott, Michael G ^b   Davies, Elizabeth ^b   Edwards, Collette ^b   Darwish Elhajji, Feras W ^a   Conlon, Geraldine ^b   Magee, Fidelma A ^b   Barr, Paul J ^a   Kearney, Mary P ^b  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b NORTHERN HEALTH AND SOCIAL CARE TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN; METRONIDAZOLE; VANCOMYCIN;

AGED; CLINICAL ARTICLE; CLOSTRIDIUM DIFFICILE INFECTION; CONTROLLED STUDY; HUMAN; LENGTH OF STAY; LETTER; MALE; SINGLE DRUG DOSE; TREATMENT OUTCOME;

AGED, 80 AND OVER; BACTERIAL TOXINS; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM INFECTIONS; ENTEROTOXINS; FEMALE; HUMANS; IMMUNOGLOBULINS, INTRAVENOUS; IMMUNOLOGIC FACTORS; LENGTH OF STAY; MALE; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 79957937615     PISSN: 0899823X     EISSN: None     Source Type: Journal    
DOI: 10.1086/660203     Document Type: Letter

References (9)

1. Thompson I. Clostridium difficile-associated disease: update and focus on non-antibiotic strategies. Age Ageing 2008;37:14-18.
2. McFarland LV. Update on the changing epidemiology of Clostridium difficile-associated disease. Nat Clin Pract Gastroenterol Hepatol 2008;5:40-48.
3. Kyne L, Warny M, Qamar A, Kelly CP. Asymptomatic carriage of Clostridium difficile and serum levels of IgG antibody against toxin A. N Engl J Med 2000;342:390-397.
4. Leffler DA, Lamont JT. Treatment of Clostridium difficile-associated disease. Gastroenterology 2009;136:1899-1912.
5. Gerding DN, Muto CA, Owens RC. Treatment of Clostridium difficile infection. Clin Infect Dis 2008;46(suppl)1:S32-S42.
6. Halsey J. Current and future treatment modalities for Clostridium difficile-associated disease. Am J Health Syst Pharm 2008;65:705-715.
7. O'Horo J, Safdar N. The role of immunoglobulin for the treatment of Clostridium difficile infection: a systematic review. Int J Infect Dis 2009;13:663-667.
8. Aldeyab MA, Devine MJ, Flanagan P, et al. Multi-hospital outbreak of Clostridium difficile ribotype 027 infection: epidemiology and analysis of control measures. Infect Control Hosp Epidemiol 2011;32(3):210-219.
9. Tobacman JK. Assessment of comorbidity: a review. Clin Perform Qual Health Care 1994;2:23-32.