An oral colon-targeting controlled release system based on resistant starch acetate: Synthetization, characterization, and preparation of film-coating pellets

Journal of Agricultural and Food Chemistry

Volumn 59, Issue 10, 2011, Pages 5738-5745

  Pu, Huayin ^a   Chen, Ling ^a   Li, Xiaoxi ^a   Xie, Fengwei ^b   Yu, Long ^a   Li, Lin ^a  

^a SOUTH CHINA UNIVERSITY OF TECHNOLOGY   (China)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Bioactive component; Colon targeting; Film coated pellets; In vitro release; Resistant starch acetate

Indexed keywords

BIOACTIVE COMPONENTS; COLON-TARGETING; FILM-COATED PELLETS; IN-VITRO; RESISTANT STARCH ACETATE;

BODY FLUIDS; COATINGS; FILM GROWTH; FLUIDIZATION; FOURIER TRANSFORM INFRARED SPECTROSCOPY; PELLETIZING; PLASTICIZERS; REINFORCED PLASTICS; STARCH; THICKNESS MEASUREMENT; VOLATILE FATTY ACIDS; X RAY DIFFRACTION; X RAY DIFFRACTION ANALYSIS;

FILM PREPARATION;

AMYLOSE; DRUG DERIVATIVE; PLASTICIZER; STARCH; STARCH ACETATE; TRIACETIN;

ARTICLE; BIOLOGICAL MODEL; CHEMISTRY; COLON; CRYSTALLIZATION; DIGESTION; DRUG DELIVERY SYSTEM; DRUG EFFECT; ESTERIFICATION; HUMAN; MAIZE; SYNTHESIS; X RAY DIFFRACTION;

AMYLOSE; COLON; CRYSTALLIZATION; DIGESTION; DRUG DELIVERY SYSTEMS; ESTERIFICATION; HUMANS; MODELS, BIOLOGICAL; PLASTICIZERS; STARCH; TRIACETIN; X-RAY DIFFRACTION; ZEA MAYS;

BOVINAE; HYDRIDA;

EID: 79957933330     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf2005468     Document Type: Article

References (46)

1. Palzer, S. Food structures for nutrition, health and wellness. Trends Food Sci. Technol. 2009, 20, 194-200.
2. Hartmann, R.; Meisel, H. Food-derived peptides with biological activity: From research to food applications. Curr. Opin. Biotechnol 2007, 18, 163-169. (Pubitemid 46575225)
3. Flanagan, J.; Singh, H. Recent Advances in the Delivery of Food-Derived Bioactives and Drugs Using Microemulsions. In Nanocarrier Technologies; Mozafari, M. R, Ed.; Springer: Netherlands, 2006; pp 95-111.
4. Champagne, C. P.; Fustier, P. Microencapsulation for the improved delivery of bioactive compounds into foods. Curr. Opin. Biotechnol. 2007, 18, 184-190. (Pubitemid 46575231)
5. McClements, D. J.; Decker, E. A; Park, Y.; Structural design principles for delivery of bioactive components in nutraceuticals and functional foods. Crit. Rev. Food Sci. Nutr. 2009, 49, 577-606.
6. Kosaraju, S. L. Colon targeted delivery systems: review of polysaccharides for encapsulation and delivery. Crit. Rev. Food Sci. Nutr. 2005, 45, 251-258. (Pubitemid 41657349)
7. Wang, X.; Li, X.; Chen, L.; Xie, F.; Yu, L.; Li, B. Preparation and characterisation of octenyl succinate starch as a delivery carrier for bioactive food components. Food Chem. 2011, 126(3), 1218-1225.
8. de Vos, P.; Faas, M. M.; Spasojevic, M.; Sikkema, J. Encapsulation for preservation of functionality and targeted delivery of bioactive food components. Int. Dairy J. 2010, 20(4), 292-302.
9. Hovgaard, L.; Brondsted, H. Current applications of polysaccharides in colon targeting. Crit. Rev. Ther. Drug 1996, 13 (3-4), 185-223. (Pubitemid 27024257)
10. Haupt, S.; Rubinstein, A. The colon as a possible target for orally administered peptide and protein drugs. Crit. Rev. Ther. Drug 2002, 19(6), 499-551. (Pubitemid 36692824)
11. Chourasia, M. K.; Jain, S. K. Pharmaceutical approaches to colon targeted drug delivery systems. J. Pharm. Pharm. Sci. 2003, 6(1), 33-66. (Pubitemid 37207241)
12. Caraballo, I. Factors affecting drug release from hydroxypropyl methylcellulose matrix systems in the light of classical and percolation theories. Expert Opin. Drug Delivery 2010, 7(11), 1291-1301.
13. Basit, A. W.; Podczeck, F.; Newton, J. M.; Waddington, W. A.; Ell, P. J.; Lacey, L. F. The use of formulation technology to assess regional gastrointestinal drug absorption in humans. Eur. J. Pharm. Sci. 2004, 21 (2-3), 179-189. (Pubitemid 38156155)
14. Huang, Y. Y.; Chung, T. W.; Tzeng, T. W. A method using biodegradable polylactides polyethylene glycol for drug release with reduced initial burst. Int. J. Pharm. 1999, 182(1), 93-100.
15. Karrout, Y.; Neut, C; Wils, D.; Siepmann, F.; Deremaux, L.; Desreumaux, P.; Siepmann, J. Novel polymeric film coatings for colon targeting: How to adjust desired membrane properties. Int. J. Pharm. 2009, 371 (1-2), 64-70.
16. Abdul, S.; Chandewar, A. V.; Jaiswal, S. B. A flexible technology for modified-release drugs: Multiple-unit pellet system (MUPS). J. Controlled Release 2010, 147(1), 2-16.
17. Dukic-Ott, A; Remon, J. P.; Foreman, P.; Vervaet, C. Immediate release of poorly soluble drugs from starch-based pellets prepared via extrusion/spheronisation. Eur. J. Pharm. Biopharm. 2007, 67(3), 715-724. (Pubitemid 47576617)
18. Dukic-Ott, A.; DeBeer, T.; Remon, J. P.; Baeyens, W.; Foreman, P.; Vervaet, C. In-vitro and in-vivo evaluation of enteric-coated starchbased pellets prepared via extrusion/spheronisation. Eur. J. Pharm. Biopharm. 2008, 70(1), 302-312.
19. Bylaite, E.; Stahnke, L. H. The effect of pectin on the release of volatile aroma compounds from a food model system. In: Flavour Research at the Dawn of the Twenty-first Century-Proceedings of the 10th Weurman Flavour Research Symposium; Le Quéré, J. L.; Etiévant, J. X., Eds.; Lavoisier: France, 2003; pp 59-62.
20. Liu, L. S.; Fishman, M. L.; Kost, J.; Hicks, K. B. Pectin-based systems for colon-specific drug delivery via oral route. Biomaterials. 2003, 24(19), 3333-3343. (Pubitemid 36581891)
21. Guilherme, M. R.; Reis, A. V.; Paulino, A. T.; Moia, T. A.; Mattoso, L. H. C; Tambourgi, E. B. Pectin-Based Polymer Hydrogel as a Carrier for Release of Agricultural Nutrients and Removal of Heavy Metals from Wastewater. J. Appl. Polym. Sci. 2010, 117(6), 3146-3154.
22. Krishnaiah, Y. S. R; Raju, P. V.; Kumar, B. D.; Satyanarayana, V.; Karthikeyan, R S.; Bhaskar, P. Pharmacokinetic evaluation of guar gum-based colon-targeted drug delivery systems of mebendazole in healthy volunteers. J. Controlled Release 2003, 88(1), 95-103. (Pubitemid 36173955)
23. Sen, G.; Mishra, S.; Jha, U.; Pal, S. Microwave initiated synthesis of polyacrylamide grafted guar gum (GG-g-PAM)-Characterizations and application as matrix for controlled release of 5-amino salicylic acid. Int. J. Biol. Macromol. 2010, 47(2), 164-170.
24. Bayat, A.; Dorkoosh, F. A; Dehpour, A. R.; Moezi, L.; Larijani, B.; Junginger, H. E.; Rafiee-Tehrani, M. Nanoparticles of quaternized chitosan derivatives as a carrier for colon delivery of insulin: Ex vivo and in vivo studies. Int. J. Pharm. 2008, 356 (1-2), 259-266.
25. Akhgari, A.; Farahmand, F.; Garekani, H. A.; Sadeghi, F.; Vandamme, T. F. Permeability and swelling studies on free films containing inulin in combination with different polymethacrylates aimed for colonic drug delivery. Eur. J. Pharm. Sci. 2006, 28(4), 307-314. (Pubitemid 43792438)
26. Liu, H; Yang, X. G.; Nie, S. F.; Wei, L. L.; Zhou, L. L.; Liu, H; Tang, R.; Pan, W. S. Chitosan-based controlled porosity osmotic pump for colon-specific delivery system: Screening of formulation variables and in vitro investigation. Int. J. Pharm. 2007, 332 (1-2), 115-124. (Pubitemid 46227777)
27. Peng, H. L.; Xiong, H; Li, J. H; Xie, M. Y.; Liu, Y. Z.; Bai, C. Q.; Chen, L. X. Vanillin cross-linked chitosan microspheres for controlled release of resveratrol. Food Chem. 2010, 121(1), 23-28.
28. Karrout, Y.; Neut, C; Wils, D.; Siepmann, F.; Deremaux, L.; Flament, M. P.; Dubreuil, L.; Desreumaux, P.; Siepmann, J. Novel polymeric film coatings for colon targeting: Drug release from coated pellets. Eur. J. Pharm. Sci. 2009, 37 (3-4), 427-433.
29. Dumoulin, Y.; Cartilier, L. H; Mateescu, M. A Cross-linked amylose tablets containing alpha-amylase: An enzymatically-controlled drug release system. J. Controlled Release 1999, 60 (2-3), 161-167. (Pubitemid 29335942)
30. Santander-Ortega, M. J.; Stauner, T.; Loretz, B.; Ortega-Vinuesa, J. L.; Bastos-Gonzalez, D.; Wenz, G; Schaefer, U. F.; Lehr, C. M. Nanoparticles made from novel starch derivatives for transdermal drug delivery. J. Controlled Release 2010, 141(1), 85-92.
31. Shibata, N; Nishumura, A; Naruhashi, K.; Nakao, Y.; Miura, R. Preparation and pharmaceutical evaluation of new sustained-release capsule including starch-sponge matrix (SSM). Biomed. Pharmacother. 2010, 64(5), 352-358.
32. Tuovinen, L.; Peltonen, S.; Jarvinen, K. Drug release from starch-acetate films. J. Controlled Release 2003, 91(3), 345-354. (Pubitemid 36976765)
33. Ali, A. E. H; AlArifi, A. Characterization and in vitro evaluation of starch based hydrogels as carriers for colon specific drug delivery systems. Carbohydr. Polym. 2009, 78(4), 725-730.
34. Alias, J.; Silva, I.; Goni, I.; Gurruchaga, M. Hydrophilic amylosebased graft copolymers for controlled protein release. Carbohydr. Polym. 2008, 74(1), 31-40.
35. Freire, A. C; Fertig, C. C; Podczeck, F.; Veiga, F.; Sousa, J. Starch-based coatings for colon-specific drug delivery. Part I: The influence of heat treatment on the physico-chemical properties of high amylose maize starches. Eur. J. Pharm. Biopharm. 2009, 72(3), 574-586.
36. Silva, I.; Gurruchaga, M.; Goni, I. Physical blends of starch graft copolymers as matrices for colon targeting drug delivery systems. Carbohydr. Polym. 2009, 76(4), 593-601.
37. Chi, H; Xu, K.; Wu, X. L.; Chen, Q.; Xue, D. H; Song, C; Zhang, W.; Wang, P. X. Effect of acetylation on the properties of corn starch. Food Chem. 2008, 106(3), 923-928. (Pubitemid 47380046)
38. Xie, W. L.; Shao, L.; Liu, Y. W. Synthesis of Starch Esters in Ionic Liquids. J. Appl. Polym. Sci. 2010, 116(1), 218-224.
39. Chen, L.; Li, X. X.; Li, L.; Guo, S. Y. Acetylated starch-based biodegradable materials with potential biomedical applications as drug delivery systems. Curr. Appl. Phys. 2007, 7, e90-e93. (Pubitemid 46283552)
40. AOAC. Total, soluble, and insoluble dietary fiber in foods. Official Methods of Analysis, 17th ed., Rev. 2; Official Method 991.43; AOAC International: Gaitherburg, MD, 2000.
41. Singh, J.; Dartois, A.; Kaur, L. Starch digestibility in food matrix: A review. Trends Food Sci. Technol. 2010, 21(4), 168-180.
42. Fuentes-Zaragoza, E.; Riquelme-Navarrete, M. J.; Sanchez-Zapata, E.; Perez-Alvarez, J. A Resistant starch as functional ingredient: A review. Food Res. Int. 2010, 43(4), 931-942.
43. Xu, Y.; Ding, W. Q.; Liu, J.; Li, Y.; Kennedy, J. F.; Gu, Q.; Shao, S. X. Preparation and characterization of organic-soluble acetylated starch nanocrystals. Carbohydr. Polym. 2010, 80(4), 1078-1084.
44. Zobel, H. F. Molecules to Granules: A Comprehensive Starch Review. Starch/Stärke 1988, 40(2), 44-50.
45. Ispas-Szabo, P.; Ravenelle, F.; Hassan, I.; Preda, M.; Mateescu, M. A. Structure-properties relationship in cross-linked high-amylose starch for use in controlled drug release. Carbohydr. Res. 2000, 323 (1-4), 163-175. (Pubitemid 30070022)
46. Van Soest, J. J. G; Tournois, H; De Wit, D.; Vliegenthart, J. J. G Short-range structure in (partially) crystalline potato starch determined with attenuated total reflectance Fourier-transform IR spectroscopy. Carbohydr. Res. 1995, 279, 201-214. (Pubitemid 26019374)