Salivary gland progenitor cell biology provides a rationale for therapeutic salivary gland regeneration

Oral Diseases

Volumn 17, Issue 5, 2011, Pages 445-449

  Lombaert, Ima ^a   Knox, S M ^a   Hoffman, M P ^a  

^a NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

Author keywords

Progenitor cells; Regeneration; Salivary gland; Stem cells

Indexed keywords

CELL SURFACE MARKER; CYTOKERATIN 5; EPIDERMAL GROWTH FACTOR RECEPTOR; GROWTH FACTOR; MUSCARINIC RECEPTOR; STEM CELL FACTOR;

CELL POPULATION; GENETIC DISORDER; HUMAN; HYPOHIDROTIC ECTODERMAL DYSPLASIA; LACRIMO AURICULAR DENTO DIGITAL SYNDROME; NERVE; NONHUMAN; PARASYMPATHETIC GANGLION; PRIORITY JOURNAL; REVIEW; SALIVARY GLAND; SALIVARY GLAND FUNCTION; STEM CELL; TISSUE REGENERATION;

ANIMALS; CELL LINEAGE; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; GANGLIA, PARASYMPATHETIC; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; REGENERATION; SALIVARY DUCTS; SALIVARY GLAND DISEASES; SALIVARY GLANDS; STEM CELLS; SUBMANDIBULAR GLAND; TISSUE ENGINEERING;

EID: 79957929703     PISSN: 1354523X     EISSN: 16010825     Source Type: Journal    
DOI: 10.1111/j.1601-0825.2010.01783.x     Document Type: Review

References (23)

1. Aframian DJ, Palmon A (2008). Current status of the development of an artificial salivary gland. Tissue Eng Part B Rev 14: 187-198.
2. Barker N, Huch M, Kujala P et al (2010). Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro. Cell Stem Cell 6: 25-36.
3. Baum BJ (2000). Prospects for re-engineering salivary glands. Adv Dent Res 14: 84-88.
4. Baum BJ, Zheng C, Cotrim AP et al (2009). Aquaporin-1 gene transfer to correct radiation-induced salivary hypofunction. Handb Exp Pharmacol, 190: 403-418.
5. Bullard T, Koek L, Roztocil E, Kingsley PD, Mirels L, Ovitt CE (2008). Ascl3 expression marks a progenitor population of both acinar and ductal cells in mouse salivary glands. Dev Biol 320: 72-78.
6. Challen GA, Boles NC, Chambers SM, Goodell MA (2010). Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1. Cell Stem Cell 6: 265-278.
7. Coppes R, Stokman M (2010). Stem cells and the repair of radiation-induced salivary gland damage. Oral Dis doi: [Epub ahead of print].
8. Coppes RP, Zeilstra LJ, Kampinga HH, Konings AW (2001). Early to late sparing of radiation damage to the parotid gland by adrenergic and muscarinic receptor agonists. Br J Cancer 85: 1055-1063.
9. David R, Shai E, Aframian DJ, Palmon A (2008). Isolation and cultivation of integrin alpha(6)beta(1)-expressing salivary gland graft cells: a model for use with an artificial salivary gland. Tissue Eng Part A 14: 331-337.
10. Feng J, van der Zwaag M, Stokman MA, van Os R, Coppes RP (2009). Isolation and characterization of human salivary gland cells for stem cell transplantation to reduce radiation-induced hyposalivation. Radiother Oncol 92: 466-471.
11. Grundmann O, Mitchell GC, Limesand KH (2009). Sensitivity of salivary glands to radiation: from animal models to therapies. J Dent Res 88: 894-903.
12. Jaskoll T, Zhou YM, Trump G, Melnick M (2003). Ectodysplasin receptor-mediated signaling is essential for embryonic submandibular salivary gland development. Anat Rec A Discov Mol Cell Evol Biol 271: 322-331.
13. Knox SM, Lombaert IMA, Reed X, Vitale-Cross L, Gutkind JS, Hoffman MP (2010). Parasympathetic innervation maintains epithelial progenitor cells during salivary organogenesis. Science 329: 1645-1647.
14. Lombaert IM, Hoffman MP (2010). Epithelial stem/progenitor cells in the embryonic mouse submandibular gland. Front Oral Biol 14: 90-106.
15. Lombaert IM, Brunsting JF, Wierenga PK et al (2008a). Rescue of salivary gland function after stem cell transplantation in irradiated glands. PLoS One 3: e2063.
16. Lombaert IM, Brunsting JF, Wierenga PK, Kampinga HH, de Haan G, Coppes RP (2008b). Keratinocyte growth factor prevents radiation damage to salivary glands by expansion of the stem/progenitor pool. Stem Cells 26: 2595-2601.
17. Mikkola ML (2009). Molecular aspects of hypohidrotic ectodermal dysplasia. Am J Med Genet A 149A: 2031-2036.
18. Patel VN, Rebustini IT, Hoffman MP (2006). Salivary gland branching morphogenesis. Differentiation 74: 349-364.
19. Pavlov IP (1906). The scientific investigation of the psychical faculties or processes in the higher animals. Science 24: 613-619.
20. Proctor GB, Carpenter GH (2007). Regulation of salivary gland function by autonomic nerves. Auton Neurosci 133: 3-18.
21. Rock JR, Onaitis MW, Rawlins EL et al (2009). Basal cells as stem cells of the mouse trachea and human airway epithelium. Proc Natl Acad Sci USA 106: 12771-12775.
22. Stingl J, Eirew P, Ricketson I et al (2006). Purification and unique properties of mammary epithelial stem cells. Nature 439: 993-997.
23. Tucker AS (2007). Salivary gland development. Semin Cell Dev Biol 18: 237-244.