Superparamagnetic iron oxides formulated in polylactide-co-glycolide/ D-alpha-tocopherol polyethylene glycol 1000 succinate (PLGA/TPGS) nanoparticles for high contrast MRI

2011 1st Middle East Conference on Biomedical Engineering, MECBME 2011

Volumn , Issue , 2011, Pages 379-381

  Prashant, Chandrasekharan ^a   Dipak, Maity ^a   Xian, Yong Cai ^b   Kai Hsiang, Chuang ^b   Jun, Ding ^a   Shen, Feng Si ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b AGENCY FOR SCIENCE   (Singapore)

Author keywords

Biocompatibility; Biodegradable polymers; Cellular and molecular imaging; Microencapsulation; Nanocomposites; Nanoprecipitation

Indexed keywords

EMULSION METHOD; ENHANCED PERMEABILITY AND RETENTIONS; GLYCOLIC ACIDS; HIGH CONTRAST; HYBRID NANOPARTICLE; IN-VIVO; LONG CIRCULATING; MICROENCAPSULATION; MOLECULAR IMAGING; MRI CONTRAST AGENTS; NANO-SIZED; NANOPRECIPITATION; NANOPRECIPITATION METHOD; PARAMETER OPTIMIZATION; POLY LACTIDE-CO-GLYCOLIDE; POLYMERIC DRUG CARRIERS; POLYMERIC MATRICES; POLYMERIC NANOPARTICLES; SUPERPARAMAGNETIC IRON OXIDES; THERAPEUTIC EFFECTS; THERMAL DECOMPOSITIONS;

BIOCOMPATIBILITY; BIOMEDICAL ENGINEERING; EMULSIFICATION; ENCAPSULATION; FUNCTIONAL POLYMERS; GLYCOLS; IRON OXIDES; LACTIC ACID; MAGNETIC RESONANCE IMAGING; NANOCOMPOSITES; NANOMAGNETICS; NANOPARTICLES; POLYETHYLENE OXIDES; POLYETHYLENES; POLYMER MATRIX COMPOSITES; PYROLYSIS; RESONANCE; SUPERPARAMAGNETISM; SURFACE ACTIVE AGENTS; THERMOPLASTICS;

POLYETHYLENE GLYCOLS;

EID: 79957921809     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/MECBME.2011.5752145     Document Type: Conference Paper

References (5)

1. D.D.Stark, R. Weissleder, G. Elizondo, P.F. Hahn, S. Saini, L.E. Todd, J. Wittenberg, and J.T. Ferrucci, "Superparamagnetic iron oxide: clinical application as a contrast agent for MR imaging of the liver," Radiology, vol. 168, (no. 2), pp. 297-301, 1988.
2. W.C. Miles, J.D. Goff, P.P. Huffstetler, C.M. Reinholz, N. Pothayee, B.L. Caba, J.S. Boyd, R.M. Davis, and J.S. Riffle, "Synthesis and colloidal properties of polyether-magnetite complexes in water and phophate-buffered saline," Langmuir, vol. 25, (no. 2), pp. 803-813, 2009.
3. C. Prashant, M. Dipak, Chan-TongYang, K.-H. Chuang, D. Jun, and S.S. Feng, "Superparamagnetic iron oxide loaded poly (lactic acid)-D-á-tocopherol polyethylene glycol 1000 succinate copolymer nanoparticles as MRI contrast agent," Biomaterials, vol. 31, (no. 21), pp. 5588-5597, 2010.
4. M. Dipak, S.G. Choo, J. Yi, D. Jun, and J.M.Xue, "Synthesis of magnetite nanoparticles via a solvent-free thermal decomposition route," J.Magn.Magn.Mater., vol. 321, (no. 9), pp. 1256, 2009.
5. H. Maeda, "SMANCS and polymer-conjugated macromolecular drugs: Advantages in cancer chemotherapy," Adv Drug Deliv Rev, vol. 46, (no. 1-3), pp. 169-185, 2001.