Interictal spikes: Harbingers or causes of epilepsy?

Neuroscience Letters

Volumn 497, Issue 3, 2011, Pages 247-250

  Staley, Kevin J ^a   White, Andrew ^b,c   Dudek, F Edward ^d  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b Children's Hospital Colorado   (United States)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Epilepsy

Indexed keywords

ANTICONVULSIVE AGENT; BENZODIAZEPINE; KAINIC ACID;

BRAIN SLICE; COMORBIDITY; DISEASE MARKER; DISEASE SEVERITY; EEG ABNORMALITY; ELECTROGRAPHY; EPILEPSY; EPILEPTIC STATE; EPILEPTOGENESIS; HUMAN; INTERICTAL SPIKE; NONHUMAN; PRIORITY JOURNAL; REVIEW; SEIZURE; SPIKE WAVE; TRAUMATIC EPILEPSY; VIDEORECORDING; WAVEFORM;

ACTION POTENTIALS; ANIMALS; BIOLOGICAL CLOCKS; BRAIN; EPILEPSY; HUMANS; MODELS, NEUROLOGICAL; NERVE NET;

EID: 79957861004     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2011.03.070     Document Type: Review

References (36)

1. Annegers J.F., Hauser W.A., Coan S.P., Rocca W.A. A population-based study of seizures after traumatic brain injuries. N. Engl. J. Med. 1998, 338:20-24.
2. Bains J.S., Longacher J.M., Staley K.J. Reciprocal interactions between CA3 network activity and strength of recurrent collateral synapses. Nat. Neurosci. 1999, 2:720-726.
3. Baykan B., Kinay D., Gokyigit A., Gurses C. Periodic lateralized epileptiform discharges: association with seizures. Seizure 2000, 9:402-406.
4. Bernhardt B.C., Worsley K.J., Kim H., Evans A.C., Bernasconi A., Bernasconi N. Longitudinal and cross-sectional analysis of atrophy in pharmacoresistant temporal lobe epilepsy. Neurology 2009, 72:1747-1754.
5. Bonilha L., Rorden C., Appenzeller S., Coan A.C., Cendes F., Li L.M. Gray matter atrophy associated with duration of temporal lobe epilepsy. Neuroimage 2006, 32:1070-1079.
6. Carmichael S.T., Chesselet M.F. Synchronous neuronal activity is a signal for axonal sprouting after cortical lesions in the adult. J. Neurosci. 2002, 22:6062-6070.
7. Cascino G.D., Kelly P.J., Sharbrough F.W., Hulihan J.F., Hirschorn K.A., Trenerry M.R. Long-term follow-up of stereotactic lesionectomy in partial epilepsy: predictive factors and electroencephalographic results. Epilepsia 1992, 33:639-644.
8. Clem R.L., Celikel T., Barth A.L. Ongoing in vivo experience triggers synaptic metaplasticity in the neocortex. Science 2008, 319:101-104.
9. Courjon J.A. The late effects of head injury. Posttraumatic Epilepty in Electroclinical Practice 1969, 215-227. Charles C. Thomas, Springfield. A.E. Walker, W.F. Caveness, M. Critchley (Eds.).
10. Dahlin M., Knutsson E., Amark P., Nergardh A. Reduction of epileptiform activity in response to low-dose clonazepam in children with epilepsy: a randomized double-blind study. Epilepsia 2000, 41:308-315.
11. de C.M., Avanzini G. Interictal spikes in focal epileptogenesis. Prog. Neurobiol. 2001, 63:541-567.
12. Dube C.M., Ravizza T., Hamamura M., Zha Q., Keebaugh A., Fok K., Andres A.L., Nalcioglu O., Obenaus A., Vezzani A., Baram T.Z. Epileptogenesis provoked by prolonged experimental febrile seizures: mechanisms and biomarkers. J. Neurosci. 2010, 30:7484-7494.
13. F.E. Dudek, K.J. Staley, Early markers of epileptogenesis following injury: implications for therapy, in this issue.
14. Dyhrfjeld-Johnsen J., Berdichevsky Y., Swiercz W., Sabolek H., Staley K.J. Interictal spikes precede ictal discharges in an organotypic hippocampal slice culture model of epileptogenesis. J. Clin. Neurophysiol. 2010, 27(6):418-424.
15. Galanopoulou A.S., Moshe S.L. The epileptic hypothesis: developmentally related arguments based on animal models. Epilepsia 2009, 50(Suppl. 7):37-42.
16. Gotman J. Epileptic networks studied with EEG-fMRI. Epilepsia 2008, 49(Suppl. 3):42-51.
17. Hellier J.L., White A., Williams P.A., Edward D.F., Staley K.J. NMDA receptor-mediated long-term alterations in epileptiform activity in experimental chronic epilepsy. Neuropharmacology 2009, 56:414-421.
18. Jennett B., Van De Sande J. EEG prediction of post-traumatic epilepsy. Epilepsia 1975, 16:251-256.
19. Kleen J.K., Scott R.C., Holmes G.L., Lenck-Santini P.P. Hippocampal interictal spikes disrupt cognition in rats. Ann. Neurol. 2010, 67:250-257.
20. Krendl R., Lurger S., Baumgartner C. Absolute spike frequency predicts surgical outcome in TLE with unilateral hippocampal atrophy. Neurology 2008, 71:413-418.
21. McBain C.J., Boden P., Hill R.G. Rat hippocampal slices 'in vitro' display spontaneous epileptiform activity following long-term organotypic culture. J. Neurosci. Methods 1989, 27:35-49.
22. Miller J.W., Gotman J. The meaning of interictal spikes in temporal lobe epilepsy: should we count them?. Neurology 2008, 71:392-393.
23. Pitkanen A., Sutula T.P. Is epilepsy a progressive disorder? Prospects for new therapeutic approaches in temporal-lobe epilepsy. Lancet Neurol. 2002, 1:173-181.
24. Rosati A., Aghakhani Y., Bernasconi A., Olivier A., Andermann F., Gotman J., Dubeau F. Intractable temporal lobe epilepsy with rare spikes is less severe than with frequent spikes. Neurology 2003, 60:1290-1295.
25. Roseman E., Woodhall B. Res. Publ. Assoc. Res. Nerv. Ment. Dis. 1946, 25:200-219.
26. Sharief M.K., Sander J.W., Shorvon S.D. The effect of oral flumazenil on interictal epileptic activity: results of a double-blind, placebo-controlled study. Epilepsy Res. 1993, 15:53-60.
27. Staley K.J., Bains J.S., Yee A., Hellier J., Longacher J.M. Statistical model relating CA3 burst probability to recovery from burst-induced depression at recurrent collateral synapses. J. Neurophysiol. 2001, 86:2736-2747.
28. Staley K.J., Dudek F.E. Role of interictal spikes in epileptogenesis. Neuroscientist 2005, 11:272-276.
29. Staley K.J., Dudek F.E. Interictal spikes and epileptogenesis. Epilepsy Currents 2006, 6:199-202.
30. Staley K.J., Longacher M., Bains J.S. Presynaptic modulation of CA3 network activity. Nat. Neurosci. 1998, 1:201-209.
31. Tao J.X., Baldwin M., Hawes-Ebersole S., Ebersole J.S. Cortical substrates of scalp EEG epileptiform discharges. J. Clin. Neurophysiol. 2007, 24:96-100.
32. Temkin N.R. Preventing and treating posttraumatic seizures: the human experience. Epilepsia 2009, 50(Suppl. 2):10-13.
33. Traub R.D., Miles R. Neuronal Networks of the Hippocampus 1991, Cambridge University Press, New York.
34. White A., Williams P.A., Hellier J.L., Clark S., Edward D.F., Staley K.J. EEG spike activity precedes epilepsy after kainate-induced status epilepticus. Epilepsia 2009.
35. Williams P.A., White A.M., Clark S., Ferraro D.J., Swiercz W., Staley K.J., Dudek F.E. Development of spontaneous recurrent seizures after kainate-induced status epilepticus. J. Neurosci. 2009, 29:2103-2112.
36. Zivin L., Marsan C.A. Incidence and prognostic significance of "epileptiform" activity in the eeg of non-epileptic subjects. Brain 1968, 91:751-778.