Highly efficient synthesis of chiral alcohols with a novel NADH-dependent reductase from Streptomyces coelicolor

Bioresource Technology

Volumn 102, Issue 14, 2011, Pages 7023-7028

  Wang, Li Juan ^a   Li, Chun Xiu ^a   Ni, Yan ^a   Zhang, Jie ^a   Liu, Xiang ^b   Xu, Jian He ^a  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b JIANGNAN UNIVERSITY   (China)

Author keywords

Asymmetric reduction; Carbonyl reductase; Ethyl (S) 4 chloro 3 hydroxybutanoate; NADH regeneration; Streptomyces coelicolor

Indexed keywords

ASYMMETRIC REDUCTION; CARBONYL REDUCTASE; ETHYL (S)-4-CHLORO-3-HYDROXYBUTANOATE; NADH REGENERATION; STREPTOMYCES COELICOLOR;

BACTERIA; CARBONYLATION; ENANTIOSELECTIVITY; ESCHERICHIA COLI; KETONES; ORGANIC COMPOUNDS;

ENZYME ACTIVITY;

2 PROPANOL; ALCOHOL; BACTERIAL DNA; BACTERIAL ENZYME; BUTYRIC ACID DERIVATIVE; CALCIUM ION; CARBONYL DERIVATIVE; CARBONYL REDUCTASE; COBALT; COPPER ION; EDETIC ACID; ETHYL 4 CHLORO 3 HYDROXYBUTANOATE; ETHYL 4 CHLORO 3 OXOBUTANOATE; GENOMIC DNA; KETONE DERIVATIVE; LEAD; LITHIUM ION; MAGNESIUM ION; MANGANESE; NICKEL; ORGANIC SOLVENT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; TOLUENE; UNCLASSIFIED DRUG; WATER; ZINC ION;

ALCOHOL; BACTERIUM; CATALYSIS; DRUG; ENZYME ACTIVITY; GENOME; HOMOGENEITY; KETONE;

ALCOHOL PRODUCTION; ARTICLE; ASYMMETRIC SYNTHESIS; CHIRALITY; CONTROLLED STUDY; ENANTIOSELECTIVITY; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME PURIFICATION; ENZYME SPECIFICITY; ENZYME STABILITY; ESCHERICHIA COLI; GENE OVEREXPRESSION; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PH; PRIORITY JOURNAL; PROCESS OPTIMIZATION; REDUCTION; STREPTOMYCES COELICOLOR; THERMOSTABILITY;

ACETOACETATES; ALCOHOLS; BIOTECHNOLOGY; EDETIC ACID; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME STABILITY; HYDROGEN-ION CONCENTRATION; IONS; KINETICS; METALS; NAD; OXIDATION-REDUCTION; OXIDOREDUCTASES; RECOMBINANT PROTEINS; SOLVENTS; STEREOISOMERISM; STREPTOMYCES COELICOLOR; SUBSTRATE SPECIFICITY; TEMPERATURE;

ESCHERICHIA COLI; STREPTOMYCES COELICOLOR;

EID: 79957851192     PISSN: 09608524     EISSN: 18732976     Source Type: Journal    
DOI: 10.1016/j.biortech.2011.04.046     Document Type: Article

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