Altered blood flow distribution in the rat spinal cord under chronic compression

Spine

Volumn 36, Issue 13, 2011, Pages 1006-1009

  Kurokawa, Ryu ^a   Murata, Hidetoshi ^b   Ogino, Masahiro ^a   Ueki, Keisuke ^a   Kim, Phyo ^a,c  

^a DOKKYO UNIVERSITY   (Japan)

^b YOKOHAMA CITY UNIVERSITY   (Japan)

^c DOKKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

chronic ischemia; fluorescent microsphere; Myelopathy; spinal cord circulation

Indexed keywords

MICROSPHERE; POLYMER; URETHAN; WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CERVICAL MYELOPATHY; CERVICAL SPINE; CONTROLLED STUDY; FLUORESCENCE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SHAM PROCEDURE; SPINAL CORD BLOOD FLOW; SPINAL CORD COMPRESSION; TISSUE WATER; WATER ABSORPTION;

ANIMALS; BLOOD FLOW VELOCITY; CERVICAL VERTEBRAE; DISEASE MODELS, ANIMAL; DOWN-REGULATION; FLUORESCENT DYES; INJECTIONS; MALE; MICROSPHERES; RATS; RATS, WISTAR; REGIONAL BLOOD FLOW; SPECTROMETRY, FLUORESCENCE; SPINAL CORD; SPINAL CORD COMPRESSION; SPINAL CORD ISCHEMIA; TIME FACTORS;

EID: 79957842106     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/BRS.0b013e3181eaf33d     Document Type: Article

References (15)

1. Teresi LM, Lufkin RB, Reicher MA, et al. Asymptomatic degenerative disk disease and spondylosis of the cervical spine: MR imaging. Radiology 1987;164:83-8. (Pubitemid 17089880)
2. Al-Mefty O, Harkey H, Marawi I, et al. Experimental chronic compressive cervical myelopathy. J Neurosurg 1993;79:550-61. (Pubitemid 23289813)
3. Henderson FC, Geddes JF, Vaccaro AR, et al. Stretch-associated injury in cervical spondylotic myelopathy: new concept and review. Neurosurgery 2005;56:1101-3; discussion 1101-3.
4. Fehlings MG, Skaf G. A review of the pathophysiology of cervical spondylotic myelopathy with insights for potential novel mechanisms drawn from traumatic spinal cord injury. Spine 1998;23:2730-7. (Pubitemid 29013985)
5. Mair WG, Druckman R. The pathology of spinal cord lesions and their relation to the clinical features in protrusion of cervical intervertebral discs; a report of four cases. Brain 1953;76:70-91.
6. Gooding MR, Wilson CB, Hoff JT. Experimental cervical myelopathy. Effects of ischemia and compression of the canine cervical spinal cord. J Neurosurg 1975;43:9-17.
7. Gooding MR, Wilson CB, Hoff JT. Experimental cervical myelopathy: autoradiographic studies of spinal cord blood flow patterns. Surg Neurol 1976;5:233-9.
8. Kim P, Haisa T, Kawamoto T, et al. Delayed myelopathy induced by chronic compression in the rat spinal cord. Ann Neurol 2004;55:503-11. (Pubitemid 38391967)
9. Powers KM, Schimmel C, Glenny RW, et al. Cerebral blood flow determinations using fluorescent microspheres: variations on the sedimentation method validated. J Neurosci Methods 1999;87:159-65. (Pubitemid 29143325)
10. Glenny RW, Bernard S, Brinkley M. Validation of fluorescentlabeled microspheres for measurement of regional organ perfusion. J Appl Physiol 1993;74:2585-97. (Pubitemid 23157092)
11. Kasahara K, Nakagawa T, Kubota T. Neuronal loss and expression of neurotrophic factors in a model of rat chronic compressive spinal cord injury. Spine 2006;31:2059-66.
12. Harkey H, Al-Mefty O, Marawi I, et al. Experimental chronic compressive cervical myelopathy: effects of decompression. J Neurosurg 1995;83:336-41.
13. Hitchon PW, Dyste GN, Osenbach RK, et al. Spinal cord blood flow in response to focal compression. J Spinal Disord 1990;3:210-9. (Pubitemid 20300305)
14. Kobrine AI, Evans DE, Rizzoli H. Correlation of spinal cord blood flow and function in experimental compression. Surg Neurol 1978;10:54-9. (Pubitemid 8369667)
15. Prinzen FW, Bassingthwaighte JB. Blood flow distributions by microsphere deposition methods. Cardiovasc Res 2000;45:13-21.