Outbreak of Pneumonia in the Setting of Fatal Pneumococcal Meningitis among US Army Trainees: Potential Role of Chlamydia pneumoniae Infection

BMC Infectious Diseases

Volumn 11, Issue , 2011, Pages

  Dawood, Fatimah S ^a   Ambrose, John F ^b   Russell, Bruce P ^c   Hawksworth, Anthony W ^d   Winchell, Jonas M ^e   Glass, Nina ^e   Thurman, Kathleen ^e   Soltis, Michele A ^b   McDonough, Erin ^d   Warner, Agnes K ^e   Weston, Emily ^e   Clemmons, Nakia S ^b   Rosen, Jennifer ^e   Mitchell, Stephanie L ^e   Faix, Dennis J ^d   Blair, Patrick J ^d   Moore, Matthew R ^e   Lowery, John ^c  

^a CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^b U S ARMY CENTER FOR HEALTH PROMOTION AND PREVENTIVE MEDICINE   (United States)

^c US Gen Leonard Wood Army Hosp   (United States)

^d NAVAL MEDICAL CENTER SAN DIEGO   (United States)

^e NATIONAL CENTER FOR IMMUNIZATION AND RESPIRATORY DISEASES   (United States)

Author keywords

Chlamydophila; Military Personnel; Pneumococcal; Pneumonia; Pneumoniae

Indexed keywords

AZITHROMYCIN; PENICILLIN G; PNEUMOCOCCUS VACCINE;

ADOLESCENT; ADULT; ARMY; ARTICLE; BACTERIAL PNEUMONIA; BACTERIUM IDENTIFICATION; CHLAMYDIAL PNEUMONIA; CHLAMYDOPHILA PNEUMONIAE; DISEASE CARRIER; DISEASE SURVEILLANCE; EPIDEMIC; FEMALE; HUMAN; INFECTION PREVENTION; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; PNEUMOCOCCAL MENINGITIS; SEROTYPE; STREPTOCOCCUS PNEUMONIA; STREPTOCOCCUS PNEUMONIAE; BACTERIAL MENINGITIS; CHLAMYDIASIS; CROSS-SECTIONAL STUDY; GENETICS; ISOLATION AND PURIFICATION; MICROBIOLOGY; MIDDLE AGED; MORTALITY; PHYSIOLOGY; SOLDIER; STATISTICS; UNITED STATES;

ADOLESCENT; ADULT; CHLAMYDIA INFECTIONS; CHLAMYDOPHILA PNEUMONIAE; CROSS-SECTIONAL STUDIES; DISEASE OUTBREAKS; FEMALE; HUMANS; MALE; MENINGITIS, PNEUMOCOCCAL; MIDDLE AGED; MILITARY PERSONNEL; PNEUMONIA, BACTERIAL; STREPTOCOCCUS PNEUMONIAE; UNITED STATES; YOUNG ADULT;

EID: 79957811217     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/1471-2334-11-157     Document Type: Article

References (19)

1. Gray GC, Callahan JD, Hawksworth AW, Fisher CA, Gaydos JC. Respiratory diseases among U.S. military personnel: countering emerging threats. Emerg Infect Dis 1999, 5:379-85. 10.3201/eid0503.990308, 2640764, 10341174.
2. Berdal BP, Scheel O, Ogaard AR, Hoel T, Gutteberg TJ, Anestad G. Spread of subclinical Chlamydia pneumoniae infection in a closed community. Scand J Infect Dis 1992, 24:431-6. 10.3109/00365549209052628, 1411308.
3. Kleemola M, Saikku P, Visakorpi R, Wang SP, Grayston JT. Epidemics of pneumonia caused by TWAR, a new Chlamydia organism, in military trainees in Finland. J Infect Dis 1988, 157:230-6. 10.1093/infdis/157.2.230, 3335808.
4. Crum NF, Wallace MR, Lamb CR, et al. Halting a pneumococcal pneumonia outbreak among United States Marine Corps trainees. Am J Prev Med 2003, 25:107-11.
5. Hirsch E, McKinney M. An epidemic of pneumococcus bronchopneumonia. J Infect Dis 1919, 24:594-617.
6. Sanchez JL, Craig SC, Kolavic S, et al. An outbreak of pneumococcal pneumonia among military personnel at high risk: control by low-dose azithromycin postexposure chemoprophylaxis. Mil Med 2003, 168:1-6.
7. Balicer RD, Zarka S, Levine H, et al. Control of Streptococcus pneumoniae serotype 5 epidemic of severe pneumonia among young army recruits by mass antibiotic treatment and vaccination. Vaccine 2010, 28:5591-6. 10.1016/j.vaccine.2010.06.031, 20599301.
8. Vainio A, Lyytikainen O, Sihvonen R, et al. An outbreak of pneumonia associated with S. pneumoniae at a military training facility in Finland in 2006. APMIS 2009, 117:488-91. 10.1111/j.1600-0463.2009.02463.x, 19594488.
9. Recommended Adult Immunization Schdule--United States. 2009, 59:1-4. Morbidity and Mortality Weekly Report 2010.
10. McDonough EA, Barrozo CP, Russell KL, Metzgar D. A multiplex PCR for detection of Mycoplasma pneumoniae, Chlamydophila pneumoniae, Legionella pneumophila, and Bordetella pertussis in clinical specimens. Mol Cell Probes 2005, 19:314-22. 10.1016/j.mcp.2005.05.002, 16024220.
11. O'Brien KL, Bronsdon MA, Dagan R, et al. Evaluation of a medium (STGG) for transport and optimal recovery of Streptococcus pneumoniae from nasopharyngeal secretions collected during field studies. J Clin Microbiol 2001, 39:1021-4. 10.1128/JCM.39.3.1021-1024.2001, 87867, 11230421.
12. Heim A, Ebnet C, Harste G, Pring-Akerblom P. Rapid and quantitative detection of human adenovirus DNA by real-time PCR. J Med Virol 2003, 70:228-39. 10.1002/jmv.10382, 12696109.
13. Mitchell SL, Budhiraja S, Thurman KA, Lanier Thacker W, Winchell JM. Evaluation of two real-time PCR chemistries for the detection of Chlamydophila pneumoniae in clinical specimens. Mol Cell Probes 2009, 23:309-11. 10.1016/j.mcp.2009.07.005, 19647071.
14. Winchell JM, Thurman KA, Mitchell SL, Thacker WL, Fields BS. Evaluation of three real-time PCR assays for detection of Mycoplasma pneumoniae in an outbreak investigation. J Clin Microbiol 2008, 46:3116-8. 10.1128/JCM.00440-08, 2546712, 18614663.
15. Musher DM, Groover JE, Reichler MR, et al. Emergence of antibody to capsular polysaccharides of Streptococcus pneumoniae during outbreaks of pneumonia: association with nasopharyngeal colonization. Clin Infect Dis 1997, 24:441-6. 10.1093/clinids/24.3.441, 9114197.
16. Ekman MR, Grayston JT, Visakorpi R, Kleemola M, Kuo CC, Saikku P. An epidemic of infections due to Chlamydia pneumoniae in military conscripts. Clin Infect Dis 1993, 17:420-5. 10.1093/clinids/17.3.420, 8218684.
17. Kauppinen MT, Herva E, Kujala P, Leinonen M, Saikku P, Syrjala H. The etiology of community-acquired pneumonia among hospitalized patients during a Chlamydia pneumoniae epidemic in Finland. J Infect Dis 1995, 172:1330-5. 10.1093/infdis/172.5.1330, 7594672.
18. Nuorti JP, Butler JC, Crutcher JM, et al. An outbreak of multidrug-resistant pneumococcal pneumonia and bacteremia among unvaccinated nursing home residents. N Engl J Med 1998, 338:1861-8. 10.1056/NEJM199806253382601, 9637804.
19. Tai SS. Streptococcus pneumoniae protein vaccine candidates: properties, activities and animal studies. Crit Rev Microbiol 2006, 32:139-53. 10.1080/10408410600822942, 16893751.