-
1
-
-
0029066110
-
Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs
-
Ou SH, Wu F, Harrich D, Garcia-Martinez LF, Gaynor RB, (1995) Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs. J Virol 69: 3584-3596.
-
(1995)
J Virol
, vol.69
, pp. 3584-3596
-
-
Ou, S.H.1
Wu, F.2
Harrich, D.3
Garcia-Martinez, L.F.4
Gaynor, R.B.5
-
2
-
-
0344256486
-
Structural diversity and functional implications of the eukaryotic TDP gene family
-
Wang HY, Wang IF, Bose J, Shen CK, (2004) Structural diversity and functional implications of the eukaryotic TDP gene family. Genomics 83: 130-139.
-
(2004)
Genomics
, vol.83
, pp. 130-139
-
-
Wang, H.Y.1
Wang, I.F.2
Bose, J.3
Shen, C.K.4
-
3
-
-
0035794665
-
Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping
-
Buratti E, Dork T, Zuccato E, Pagani F, Romano M, et al. (2001) Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping. EMBO J 20: 1774-1784.
-
(2001)
EMBO J
, vol.20
, pp. 1774-1784
-
-
Buratti, E.1
Dork, T.2
Zuccato, E.3
Pagani, F.4
Romano, M.5
-
4
-
-
57649174592
-
TDP-43 overexpression enhances exon 7 inclusion during the survival of motor neuron pre-mRNA splicing
-
Bose JK, Wang IF, Hung L, Tarn WY, Shen CK, (2008) TDP-43 overexpression enhances exon 7 inclusion during the survival of motor neuron pre-mRNA splicing. J Biol Chem 283: 28852-28859.
-
(2008)
J Biol Chem
, vol.283
, pp. 28852-28859
-
-
Bose, J.K.1
Wang, I.F.2
Hung, L.3
Tarn, W.Y.4
Shen, C.K.5
-
5
-
-
42449163952
-
TDP-43, the signature protein of FTLD-U, is a neuronal activity-responsive factor
-
Wang IF, Wu LS, Chang HY, Shen CK, (2008) TDP-43, the signature protein of FTLD-U, is a neuronal activity-responsive factor. J Neurochem 105: 797-806.
-
(2008)
J Neurochem
, vol.105
, pp. 797-806
-
-
Wang, I.F.1
Wu, L.S.2
Chang, H.Y.3
Shen, C.K.4
-
6
-
-
0035965309
-
Characterization and functional implications of the RNA binding properties of nuclear factor TDP-43, a novel splicing regulator of CFTR exon 9
-
Buratti E, Baralle FE, (2001) Characterization and functional implications of the RNA binding properties of nuclear factor TDP-43, a novel splicing regulator of CFTR exon 9. J Biol Chem 276: 36337-36343.
-
(2001)
J Biol Chem
, vol.276
, pp. 36337-36343
-
-
Buratti, E.1
Baralle, F.E.2
-
7
-
-
64549100193
-
Structural insights into TDP-43 in nucleic-acid binding and domain interactions
-
Kuo PH, Doudeva LG, Wang YT, Shen CK, Yuan HS, (2009) Structural insights into TDP-43 in nucleic-acid binding and domain interactions. Nucleic Acids Res 37: 1799-1808.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 1799-1808
-
-
Kuo, P.H.1
Doudeva, L.G.2
Wang, Y.T.3
Shen, C.K.4
Yuan, H.S.5
-
8
-
-
27844514227
-
TDP-43 binds heterogeneous nuclear ribonucleoprotein A/B through its C-terminal tail: an important region for the inhibition of cystic fibrosis transmembrane conductance regulator exon 9 splicing
-
Buratti E, Brindisi A, Giombi M, Tisminetzky S, Ayala YM, et al. (2005) TDP-43 binds heterogeneous nuclear ribonucleoprotein A/B through its C-terminal tail: an important region for the inhibition of cystic fibrosis transmembrane conductance regulator exon 9 splicing. J Biol Chem 280: 37572-37584.
-
(2005)
J Biol Chem
, vol.280
, pp. 37572-37584
-
-
Buratti, E.1
Brindisi, A.2
Giombi, M.3
Tisminetzky, S.4
Ayala, Y.M.5
-
9
-
-
54249100481
-
TDP-43: an emerging new player in neurodegenerative diseases
-
Wang IF, Wu LS, Shen CK, (2008) TDP-43: an emerging new player in neurodegenerative diseases. Trends Mol Med 14: 479-485.
-
(2008)
Trends Mol Med
, vol.14
, pp. 479-485
-
-
Wang, I.F.1
Wu, L.S.2
Shen, C.K.3
-
10
-
-
33750716074
-
TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Arai T, Hasegawa M, Akiyama H, Ikeda K, Nonaka T, et al. (2006) TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Biochem Biophys Res Commun 351: 602-611.
-
(2006)
Biochem Biophys Res Commun
, vol.351
, pp. 602-611
-
-
Arai, T.1
Hasegawa, M.2
Akiyama, H.3
Ikeda, K.4
Nonaka, T.5
-
11
-
-
33749632259
-
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Neumann M, Sampathu DM, Kwong LK, Truax AC, Micsenyi MC, et al. (2006) Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 314: 130-133.
-
(2006)
Science
, vol.314
, pp. 130-133
-
-
Neumann, M.1
Sampathu, D.M.2
Kwong, L.K.3
Truax, A.C.4
Micsenyi, M.C.5
-
13
-
-
34848921202
-
Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43
-
Zhang YJ, Xu YF, Dickey CA, Buratti E, Baralle F, et al. (2007) Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43. J Neurosci 27: 10530-10534.
-
(2007)
J Neurosci
, vol.27
, pp. 10530-10534
-
-
Zhang, Y.J.1
Xu, Y.F.2
Dickey, C.A.3
Buratti, E.4
Baralle, F.5
-
14
-
-
59649086176
-
Molecular Neuropathology of TDP-43 Proteinopathies
-
Neumann M, (2009) Molecular Neuropathology of TDP-43 Proteinopathies. Int J Mol Sci 10: 232-246.
-
(2009)
Int J Mol Sci
, vol.10
, pp. 232-246
-
-
Neumann, M.1
-
15
-
-
66149114101
-
Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity
-
Zhang YJ, Xu YF, Cook C, Gendron TF, Roettges P, et al. (2009) Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity. Proc Natl Acad Sci USA 106: 7607-7612.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 7607-7612
-
-
Zhang, Y.J.1
Xu, Y.F.2
Cook, C.3
Gendron, T.F.4
Roettges, P.5
-
16
-
-
67649797399
-
Expression of TDP-43 C-terminal Fragments in Vitro Recapitulates Pathological Features of TDP-43 Proteinopathies
-
Igaz LM, Kwong LK, Chen-Plotkin A, Winton MJ, Unger TL, et al. (2009) Expression of TDP-43 C-terminal Fragments in Vitro Recapitulates Pathological Features of TDP-43 Proteinopathies. J Biol Chem 284: 8516-8524.
-
(2009)
J Biol Chem
, vol.284
, pp. 8516-8524
-
-
Igaz, L.M.1
Kwong, L.K.2
Chen-Plotkin, A.3
Winton, M.J.4
Unger, T.L.5
-
17
-
-
77949908515
-
Phosphorylated and cleaved TDP-43 in ALS, FTLD and other neurodegenerative disorders and in cellular models of TDP-43 proteinopathy
-
Arai T, Hasegawa M, Nonoka T, Kametani F, Yamashita M, et al. (2010) Phosphorylated and cleaved TDP-43 in ALS, FTLD and other neurodegenerative disorders and in cellular models of TDP-43 proteinopathy. Neuropathology 30: 170-181.
-
(2010)
Neuropathology
, vol.30
, pp. 170-181
-
-
Arai, T.1
Hasegawa, M.2
Nonoka, T.3
Kametani, F.4
Yamashita, M.5
-
18
-
-
77951236534
-
Ubiquilin modifies TDP-43 toxicity in a Drosophila model of amyotrophic lateral sclerosis (ALS)
-
Hanson KA, Kim SH, Wassarman DA, Tibbetts RS, (2010) Ubiquilin modifies TDP-43 toxicity in a Drosophila model of amyotrophic lateral sclerosis (ALS). J Biol Chem 285: 11068-11072.
-
(2010)
J Biol Chem
, vol.285
, pp. 11068-11072
-
-
Hanson, K.A.1
Kim, S.H.2
Wassarman, D.A.3
Tibbetts, R.S.4
-
19
-
-
77649258646
-
A Drosophila model for TDP-43 proteinopathy
-
Li Y, Ray P, Rao EJ, Shi C, Guo W, et al. (2010) A Drosophila model for TDP-43 proteinopathy. Proc Natl Acad Sci USA 107: 3169-3174.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 3169-3174
-
-
Li, Y.1
Ray, P.2
Rao, E.J.3
Shi, C.4
Guo, W.5
-
20
-
-
77955395385
-
Elevated expression of TDP-43 in the forebrain of mice is sufficient to cause neurological and pathological phenotypes mimicking FTLD-U
-
Tsai KJ, Yang CH, Fang YH, Cho KH, Chien WL, et al. (2010) Elevated expression of TDP-43 in the forebrain of mice is sufficient to cause neurological and pathological phenotypes mimicking FTLD-U. J Exp Med 207: 1661-1673.
-
(2010)
J Exp Med
, vol.207
, pp. 1661-1673
-
-
Tsai, K.J.1
Yang, C.H.2
Fang, Y.H.3
Cho, K.H.4
Chien, W.L.5
-
21
-
-
77649269011
-
TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration
-
Wils H, Kleinberger G, Janssens J, Pereson S, Joris G, et al. (2010) TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration. Proc Natl Acad Sci USA 107: 3858-3863.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 3858-3863
-
-
Wils, H.1
Kleinberger, G.2
Janssens, J.3
Pereson, S.4
Joris, G.5
-
23
-
-
67349271683
-
Depletion of TDP-43 affects Drosophila motoneurons terminal synapsis and locomotive behavior
-
Feiguin F, Godena VK, Romano G, D'Ambrogio A, Klima R, et al. (2009) Depletion of TDP-43 affects Drosophila motoneurons terminal synapsis and locomotive behavior. FEBS Lett 583: 1586-1592.
-
(2009)
FEBS Lett
, vol.583
, pp. 1586-1592
-
-
Feiguin, F.1
Godena, V.K.2
Romano, G.3
D'Ambrogio, A.4
Klima, R.5
-
24
-
-
70350356317
-
Frontotemporal dementia and amyotrophic lateral sclerosis-associated disease protein TDP-43 promotes dendritic branching
-
Lu Y, Ferris J, Gao FB, (2009) Frontotemporal dementia and amyotrophic lateral sclerosis-associated disease protein TDP-43 promotes dendritic branching. Mol Brain 2: 30.
-
(2009)
Mol Brain
, vol.2
, pp. 30
-
-
Lu, Y.1
Ferris, J.2
Gao, F.B.3
-
25
-
-
0030449882
-
Associative learning disrupted by impaired Gs signaling in Drosophila mushroom bodies
-
Connolly JB, Roberts IJ, Armstrong JD, Kaiser K, Forte M, et al. (1996) Associative learning disrupted by impaired Gs signaling in Drosophila mushroom bodies. Science 274: 2104-2107.
-
(1996)
Science
, vol.274
, pp. 2104-2107
-
-
Connolly, J.B.1
Roberts, I.J.2
Armstrong, J.D.3
Kaiser, K.4
Forte, M.5
-
26
-
-
0034724897
-
Localization of a short-term memory in Drosophila
-
Zars T, Fischer M, Schulz R, Heisenberg M, (2000) Localization of a short-term memory in Drosophila. Science 288: 672-675.
-
(2000)
Science
, vol.288
, pp. 672-675
-
-
Zars, T.1
Fischer, M.2
Schulz, R.3
Heisenberg, M.4
-
27
-
-
0032821487
-
Development of the Drosophila mushroom bodies: sequential generation of three distinct types of neurons from a neuroblast
-
Lee T, Lee A, Luo L, (1999) Development of the Drosophila mushroom bodies: sequential generation of three distinct types of neurons from a neuroblast. Development 126: 4065-4076.
-
(1999)
Development
, vol.126
, pp. 4065-4076
-
-
Lee, T.1
Lee, A.2
Luo, L.3
-
28
-
-
77949878273
-
TDP-43 is a developmentally regulated protein essential for early embryonic development
-
Sephton CF, Good SK, Atkin S, Dewey CM, Mayer P 3rd, et al. (2010) TDP-43 is a developmentally regulated protein essential for early embryonic development. J Biol Chem 285: 6826-6834.
-
(2010)
J Biol Chem
, vol.285
, pp. 6826-6834
-
-
Sephton, C.F.1
Good, S.K.2
Atkin, S.3
Dewey, C.M.4
Mayer III, P.5
-
29
-
-
74749107048
-
TDP-43, a neuro-pathosignature factor, is essential for early mouse embryogenesis
-
Wu LS, Cheng WC, Hou SC, Yan YT, Jiang ST, et al. (2010) TDP-43, a neuro-pathosignature factor, is essential for early mouse embryogenesis. Genesis 48: 56-62.
-
(2010)
Genesis
, vol.48
, pp. 56-62
-
-
Wu, L.S.1
Cheng, W.C.2
Hou, S.C.3
Yan, Y.T.4
Jiang, S.T.5
-
30
-
-
77949897022
-
Amyotrophic lateral sclerosis and frontotemporal lobar degeneration: a spectrum of TDP-43 proteinopathies
-
Geser F, Lee VM, Trojanowski JQ, (2010) Amyotrophic lateral sclerosis and frontotemporal lobar degeneration: a spectrum of TDP-43 proteinopathies. Neuropathology 30: 103-112.
-
(2010)
Neuropathology
, vol.30
, pp. 103-112
-
-
Geser, F.1
Lee, V.M.2
Trojanowski, J.Q.3
-
31
-
-
0034934752
-
Flies, genes, and learning
-
Waddell S, Quinn WG, (2001) Flies, genes, and learning. Annu Rev Neurosci 24: 1283-1309.
-
(2001)
Annu Rev Neurosci
, vol.24
, pp. 1283-1309
-
-
Waddell, S.1
Quinn, W.G.2
-
32
-
-
57049149602
-
Increased TDP-43 protein in cerebrospinal fluid of patients with amyotrophic lateral sclerosis
-
Kasai T, Tokuda T, Ishigami N, Sasayama H, Foulds P, et al. (2009) Increased TDP-43 protein in cerebrospinal fluid of patients with amyotrophic lateral sclerosis. Acta Neuropathol 117: 55-62.
-
(2009)
Acta Neuropathol
, vol.117
, pp. 55-62
-
-
Kasai, T.1
Tokuda, T.2
Ishigami, N.3
Sasayama, H.4
Foulds, P.5
-
33
-
-
34447099071
-
Gene expression analysis of frontotemporal lobar degeneration of the motor neuron disease type with ubiquitinated inclusions
-
Mishra M, Paunesku T, Woloschak GE, Siddique T, Zhu LJ, et al. (2007) Gene expression analysis of frontotemporal lobar degeneration of the motor neuron disease type with ubiquitinated inclusions. Acta Neuropathol 114: 81-94.
-
(2007)
Acta Neuropathol
, vol.114
, pp. 81-94
-
-
Mishra, M.1
Paunesku, T.2
Woloschak, G.E.3
Siddique, T.4
Zhu, L.J.5
-
34
-
-
73249152831
-
TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration
-
Wegorzewska I, Bell S, Cairns NJ, Miller TM, Baloh RH, (2009) TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration. Proc Natl Acad Sci USA 106: 18809-18814.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 18809-18814
-
-
Wegorzewska, I.1
Bell, S.2
Cairns, N.J.3
Miller, T.M.4
Baloh, R.H.5
-
35
-
-
77950421249
-
Transgenic rat model of neurodegeneration caused by mutation in the TDP gene
-
Zhou H, Huang C, Chen H, Wang D, Landel CP, et al. (2010) Transgenic rat model of neurodegeneration caused by mutation in the TDP gene. PLoS Genet 6: e1000887.
-
(2010)
PLoS Genet
, vol.6
-
-
Zhou, H.1
Huang, C.2
Chen, H.3
Wang, D.4
Landel, C.P.5
-
36
-
-
17144426507
-
Human, Drosophila, and C.elegans TDP43: nucleic acid binding properties and splicing regulatory function
-
Ayala YM, Pantano S, D'Ambrogio A, Buratti E, Brindisi A, et al. (2005) Human, Drosophila, and C.elegans TDP43: nucleic acid binding properties and splicing regulatory function. J Mol Biol 348: 575-588.
-
(2005)
J Mol Biol
, vol.348
, pp. 575-588
-
-
Ayala, Y.M.1
Pantano, S.2
D'Ambrogio, A.3
Buratti, E.4
Brindisi, A.5
-
37
-
-
0000064419
-
Behavioral mutants of Drosophila isolated by countercurrent distribution
-
Benzer S, (1967) Behavioral mutants of Drosophila isolated by countercurrent distribution. Proc Natl Acad Sci USA 58: 1112-1119.
-
(1967)
Proc Natl Acad Sci USA
, vol.58
, pp. 1112-1119
-
-
Benzer, S.1
-
38
-
-
0022119763
-
Classical conditioning and retention in normal and mutant Drosophila melanogaster
-
Tully T, Quinn WG, (1985) Classical conditioning and retention in normal and mutant Drosophila melanogaster. J Comp Physiol 157: 263-277.
-
(1985)
J Comp Physiol
, vol.157
, pp. 263-277
-
-
Tully, T.1
Quinn, W.G.2
-
39
-
-
44749091997
-
Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation
-
Winton MJ, Igaz LM, Wong MM, Kwong LK, Trojanowski JQ, et al. (2008) Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation. J Biol Chem 283: 13302-13309.
-
(2008)
J Biol Chem
, vol.283
, pp. 13302-13309
-
-
Winton, M.J.1
Igaz, L.M.2
Wong, M.M.3
Kwong, L.K.4
Trojanowski, J.Q.5
|