Impact of phenotype definition on genome-wide association signals: Empirical evaluation in human immunodeficiency virus type 1 infection

American Journal of Epidemiology

Volumn 173, Issue 11, 2011, Pages 1336-1342

  Evangelou, Evangelos ^a,b   Fellay, Jacques ^c   Colombo, Sara ^a   Martinez Picado, Javier ^d,e   Obel, Niels ^f   Goldstein, David B ^c   Telenti, Amalio ^a   Ioannidis, John P A ^b,g,h,i  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b UNIVERSITY OF IOANNINA   (Greece)

^c DUKE UNIVERSITY   (United States)

^d HOSPITAL UNIVERSITARI GERMANS TRIAS I PUJOL   (Spain)

^e INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

^f Rigshospitalet   (Denmark)

^g TUFTS MEDICAL CENTER   (United States)

^h HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

ⁱ STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

genome wide association study; HIV seropositivity; HIV seroprevalence; phenotype; seroepidemiologic studies

Indexed keywords

CHROMOSOME; DISEASE PREVALENCE; EMPIRICAL ANALYSIS; EPIDEMIOLOGY; GENOME; HUMAN IMMUNODEFICIENCY VIRUS; INFECTIVITY; PHENOTYPE; POLYMORPHISM; SAMPLE PREPARATION; SERUM; SIGNAL;

ADULT; ARTICLE; CLINICAL ASSESSMENT; EFFECT SIZE; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; MAJOR CLINICAL STUDY; MALE; NONHUMAN; PHENOTYPE; SEROCONVERSION; SEROPREVALENCE; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; VIRUS LOAD;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 79957793279     PISSN: 00029262     EISSN: 14766256     Source Type: Journal    
DOI: 10.1093/aje/kwr024     Document Type: Article

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