Piezoelectric permeabilization of mammalian dermal tissue for in vivo DNA delivery leads to enhanced protein expression and increased immunogenicity

Human Vaccines

Volumn 7, Issue SUPPL., 2011, Pages 22-28

  Broderick, Kate E ^a   Kardos, Thomas ^a   McCoy, Jay R ^a   Fons, Michael P ^a   Kemmerrer, Stephen ^a   Sardesai, Niranjan Y ^a  

^a Inovio Pharmaceuticals Inc   (United States)

Author keywords

DNA vaccine; Electropermeabilization; Electroporation; Gene transfer; Piezo electric; Spark

Indexed keywords

DNA VACCINE; GREEN FLUORESCENT PROTEIN; INFLUENZA ANTIGEN NUCLEAR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; CONTROLLED STUDY; DNA IMMUNIZATION; DRUG DELIVERY SYSTEM; ELECTROPORATION; FEMALE; GENE LOCATION; GENE TRANSFER; GUINEA PIG; HISTOLOGY; HUMORAL IMMUNITY; IMMUNOGENICITY; IN VIVO STUDY; NONHUMAN; PIEZO SPARK INTRADERMAL DELIVERY DEVICE; PIEZOELECTRICITY; PROTEIN EXPRESSION; REVIEW; TISSUE SECTION;

ANIMALS; ANTIGENS; DERMIS; ELECTROPORATION; GENE EXPRESSION; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; GUINEA PIGS; PERMEABILITY; PLASMIDS; VACCINATION; VACCINES, DNA;

EID: 79957739845     PISSN: 15548600     EISSN: 15548619     Source Type: Journal    
DOI: 10.4161/hv.7.0.14559     Document Type: Review

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